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Literature DB >> 24827472

An ensemble of aptamers and antibodies for multivalent capture of cancer cells.

Jinling Zhang¹, Weian Sheng, Z Hugh Fan.

Abstract

We developed an optimized ensemble of aptamers and antibodies that functions as a multivalent adhesive domain for the capture and isolation of cancer cells. When incorporated into a microfluidic device, the ensemble showed not only high capture efficiency, but also superior capture selectivity at a high shear stress (or high flow rate).

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Year: 2014 PMID： 24827472 PMCID： PMC4255561 DOI： 10.1039/c4cc02002b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

28 in total

1. On the nature of the multivalency effect: a thermodynamic model.

Authors: Pavel I Kitov; David R Bundle
Journal: J Am Chem Soc Date: 2003-12-31 Impact factor: 15.419

2. Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays.

Authors: Antoine-Emmanuel Saliba; Laure Saias; Eleni Psychari; Nicolas Minc; Damien Simon; François-Clément Bidard; Claire Mathiot; Jean-Yves Pierga; Vincent Fraisier; Jean Salamero; Véronique Saada; Françoise Farace; Philippe Vielh; Laurent Malaquin; Jean-Louis Viovy
Journal: Proc Natl Acad Sci U S A Date: 2010-08-02 Impact factor: 11.205

3. Portable filter-based microdevice for detection and characterization of circulating tumor cells.

Authors: Henry K Lin; Siyang Zheng; Anthony J Williams; Marija Balic; Susan Groshen; Howard I Scher; Martin Fleisher; Walter Stadler; Ram H Datar; Yu-Chong Tai; Richard J Cote
Journal: Clin Cancer Res Date: 2010-09-28 Impact factor: 12.531

4. Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices.

Authors: Weian Sheng; Tao Chen; Weihong Tan; Z Hugh Fan
Journal: ACS Nano Date: 2013-07-15 Impact factor: 15.881

5. Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells.

Authors: Shutao Wang; Hao Wang; Jing Jiao; Kuan-Ju Chen; Gwen E Owens; Ken-ichiro Kamei; Jing Sun; David J Sherman; Christian P Behrenbruch; Hong Wu; Hsian-Rong Tseng
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

6. Microchip-based immunomagnetic detection of circulating tumor cells.

Authors: Kazunori Hoshino; Yu-Yen Huang; Nancy Lane; Michael Huebschman; Jonathan W Uhr; Eugene P Frenkel; Xiaojing Zhang
Journal: Lab Chip Date: 2011-08-24 Impact factor: 6.799

7. Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.

Authors: Jason P Gleghorn; Erica D Pratt; Denise Denning; He Liu; Neil H Bander; Scott T Tagawa; David M Nanus; Paraskevi A Giannakakou; Brian J Kirby
Journal: Lab Chip Date: 2009-11-16 Impact factor: 6.799

8. Detecting carcinoma cells in peripheral blood of patients with hepatocellular carcinoma by immunomagnetic beads and rt-PCR.

Authors: Junming Guo; Feng Yao; Yanlu Lou; Changfeng Xu; Bingxiu Xiao; Wenhong Zhou; Jian Chen; Yaoren Hu; Zhong Liu
Journal: J Clin Gastroenterol Date: 2007-09 Impact factor: 3.062

9. Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor.

Authors: André A Adams; Paul I Okagbare; Juan Feng; Matuesz L Hupert; Don Patterson; Jost Göttert; Robin L McCarley; Dimitris Nikitopoulos; Michael C Murphy; Steven A Soper
Journal: J Am Chem Soc Date: 2008-06-17 Impact factor: 15.419

10. Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood.

Authors: Stephen D Mikolajczyk; Lisa S Millar; Pavel Tsinberg; Stephen M Coutts; Maryam Zomorrodi; Tam Pham; Farideh Z Bischoff; Tony J Pircher
Journal: J Oncol Date: 2011-04-19 Impact factor: 4.375

8 in total

1. A paper/polymer hybrid CD-like microfluidic SpinChip integrated with DNA-functionalized graphene oxide nanosensors for multiplex qLAMP detection.

Authors: Maowei Dou; Sharma T Sanjay; Delfina C Dominguez; Sihui Zhan; XiuJun Li
Journal: Chem Commun (Camb) Date: 2017-10-03 Impact factor: 6.222

An ensemble of aptamers and antibodies for multivalent capture of cancer cells.

1. On the nature of the multivalency effect: a thermodynamic model.

2. Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays.

3. Portable filter-based microdevice for detection and characterization of circulating tumor cells.

4. Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices.

5. Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells.

6. Microchip-based immunomagnetic detection of circulating tumor cells.

7. Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.

8. Detecting carcinoma cells in peripheral blood of patients with hepatocellular carcinoma by immunomagnetic beads and rt-PCR.

9. Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor.

10. Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood.

1. A paper/polymer hybrid CD-like microfluidic SpinChip integrated with DNA-functionalized graphene oxide nanosensors for multiplex qLAMP detection.

2. Tumor cell capture patterns around aptamer-immobilized microposts in microfluidic devices.

3. Single-Cell Mechanical Characteristics Analyzed by Multiconstriction Microfluidic Channels.

Review 4. Circulating Tumor Cell Isolation and Analysis.

Review 5. Recent Progress of Microfluidics in Translational Applications.

6. Multiplexed instrument-free meningitis diagnosis on a polymer/paper hybrid microfluidic biochip.

Review 7. Micro- and nanodevices integrated with biomolecular probes.

8. Single-cell mRNA cytometry via sequence-specific nanoparticle clustering and trapping.