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Literature DB >> 24825350

SIRT2 controls the pentose phosphate switch.

Lindsay E Wu¹, David A Sinclair².

Abstract

Entities: Chemical Gene

Mesh：

Substances：

Year: 2014 PMID： 24825350 PMCID： PMC4194117 DOI： 10.15252/embj.201488713

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

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9 in total

1. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.

Authors: Hyun-Seok Kim; Athanassios Vassilopoulos; Rui-Hong Wang; Tyler Lahusen; Zhen Xiao; Xiaoling Xu; Cuiling Li; Timothy D Veenstra; Bing Li; Hongtao Yu; Junfang Ji; Xin Wei Wang; Seong-Hoon Park; Yong I Cha; David Gius; Chu-Xia Deng
Journal: Cancer Cell Date: 2011-10-18 Impact factor: 31.743

2. Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress.

Authors: Yi-Ping Wang; Li-Sha Zhou; Yu-Zheng Zhao; Shi-Wen Wang; Lei-Lei Chen; Li-Xia Liu; Zhi-Qiang Ling; Fu-Jun Hu; Yi-Ping Sun; Jing-Ye Zhang; Chen Yang; Yi Yang; Yue Xiong; Kun-Liang Guan; Dan Ye
Journal: EMBO J Date: 2014-04-25 Impact factor: 11.598

3. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice.

Authors: Jun Yoshino; Kathryn F Mills; Myeong Jin Yoon; Shin-ichiro Imai
Journal: Cell Metab Date: 2011-10-05 Impact factor: 27.287

4. Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells.

Authors: Shi Pan; Cameron J World; Christopher J Kovacs; Bradford C Berk
Journal: Arterioscler Thromb Vasc Biol Date: 2009-04-09 Impact factor: 8.311

5. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

Authors: Ana P Gomes; Nathan L Price; Alvin J Y Ling; Javid J Moslehi; Magdalene K Montgomery; Luis Rajman; James P White; João S Teodoro; Christiane D Wrann; Basil P Hubbard; Evi M Mercken; Carlos M Palmeira; Rafael de Cabo; Anabela P Rolo; Nigel Turner; Eric L Bell; David A Sinclair
Journal: Cell Date: 2013-12-19 Impact factor: 41.582

6. Effects of aging on the recycling via the pentose cycle and on the kinetics of glycogen and protein metabolism in various organs of the rat.

Authors: H Niedermüller
Journal: Arch Gerontol Geriatr Date: 1986-12 Impact factor: 3.250

7. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.

Authors: Carles Cantó; Riekelt H Houtkooper; Eija Pirinen; Dou Y Youn; Maaike H Oosterveer; Yana Cen; Pablo J Fernandez-Marcos; Hiroyasu Yamamoto; Pénélope A Andreux; Philippe Cettour-Rose; Karl Gademann; Chris Rinsch; Kristina Schoonjans; Anthony A Sauve; Johan Auwerx
Journal: Cell Metab Date: 2012-06-06 Impact factor: 27.287

8. Glucose-6-phosphate dehydrogenase deficiency and type 2 diabetes.

Authors: Anthony D Heymann; Yossi Cohen; Gabriel Chodick
Journal: Diabetes Care Date: 2012-08 Impact factor: 19.112

9. Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.

Authors: Markus Ralser; Mirjam M Wamelink; Axel Kowald; Birgit Gerisch; Gino Heeren; Eduard A Struys; Edda Klipp; Cornelis Jakobs; Michael Breitenbach; Hans Lehrach; Sylvia Krobitsch
Journal: J Biol Date: 2007-12-21

9 in total

5 in total

SIRT2 controls the pentose phosphate switch.

1. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.

2. Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress.

3. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice.

4. Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells.

5. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

6. Effects of aging on the recycling via the pentose cycle and on the kinetics of glycogen and protein metabolism in various organs of the rat.

7. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.

8. Glucose-6-phosphate dehydrogenase deficiency and type 2 diabetes.

9. Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.

Review 1. NAD⁺ in Brain Aging and Neurodegenerative Disorders.

Review 2. Mitochondria Turnover and Lysosomal Function in Hematopoietic Stem Cell Metabolism.

3. SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation.

Review 4. Metabolic Regulation of Hematopoietic Stem Cells.

Review 5. NAD⁺ metabolism, stemness, the immune response, and cancer.

Review 1. NAD+ in Brain Aging and Neurodegenerative Disorders.

Review 2. Mitochondria Turnover and Lysosomal Function in Hematopoietic Stem Cell Metabolism.

Review 4. Metabolic Regulation of Hematopoietic Stem Cells.

Review 5. NAD+ metabolism, stemness, the immune response, and cancer.

Review 1. NAD⁺ in Brain Aging and Neurodegenerative Disorders.

Review 5. NAD⁺ metabolism, stemness, the immune response, and cancer.