Literature DB >> 24825222

Preparing for rectal microbicides: sociocultural factors affecting product uptake among potential South American users.

Jerome T Galea1, Janni J Kinsler, John Imrie, César R Nureña, Lucía Ruiz, Luis Fernando Galarza, Jorge Sánchez, William E Cunningham.   

Abstract

OBJECTIVES: We examined views on rectal microbicides (RMs), a potential HIV prevention option, among men who have sex with men and transgender women in 3 South American cities.
METHODS: During September 2009 to September 2010, we conducted 10 focus groups and 36 in-depth interviews (n = 140) in Lima and Iquitos, Peru, and Guayaquil, Ecuador, to examine 5 RM domains: knowledge, thoughts and opinions about RM as an HIV prevention tool, use, condoms, and social concerns. We coded emergent themes in recorded and transcribed data sets and extracted representative quotes. We collected sociodemographic information with a self-administered questionnaire.
RESULTS: RM issues identified included limited knowledge; concerns regarding plausibility, side effects, and efficacy; impact on condom use; target users (insertive vs receptive partners); and access concerns.
CONCLUSIONS: Understanding the sociocultural issues affecting RMs is critical to their uptake and should be addressed prior to product launch.

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Year:  2014        PMID: 24825222      PMCID: PMC4062029          DOI: 10.2105/AJPH.2013.301731

Source DB:  PubMed          Journal:  Am J Public Health        ISSN: 0090-0036            Impact factor:   9.308


  36 in total

1.  Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda.

Authors:  R H Gray; M J Wawer; R Brookmeyer; N K Sewankambo; D Serwadda; F Wabwire-Mangen; T Lutalo; X Li; T vanCott; T C Quinn
Journal:  Lancet       Date:  2001-04-14       Impact factor: 79.321

2.  Frequent use of lubricants for anal sex among men who have sex with men: the HIV prevention potential of a microbicidal gel.

Authors:  A Carballo-Diéguez; Z Stein; H Sáez; C Dolezal; L Nieves-Rosa; F Díaz
Journal:  Am J Public Health       Date:  2000-07       Impact factor: 9.308

3.  Homophobia? No, homoprejudice.

Authors:  C R Logan
Journal:  J Homosex       Date:  1996

4.  Effectiveness of condoms in preventing HIV transmission.

Authors:  S D Pinkerton; P R Abramson
Journal:  Soc Sci Med       Date:  1997-05       Impact factor: 4.634

5.  A continuing HIV epidemic and differential patterns of HIV-STI risk among MSM in Quito, Ecuador: an urgent need to scale up HIV testing and prevention.

Authors:  Jerry O Jacobson; Amaya Sánchez-Gómez; Orlando Montoya; Efrain Soria; Wilmer Tarupi; Marcelo Chiriboga Urquizo; Eliana Champutiz Ortiz; Sonia Morales Miranda; Rodrigo Tobar; Bertha Gómez; Celia Riera
Journal:  AIDS Behav       Date:  2014-01

6.  Per-contact risk of human immunodeficiency virus transmission between male sexual partners.

Authors:  E Vittinghoff; J Douglas; F Judson; D McKirnan; K MacQueen; S P Buchbinder
Journal:  Am J Epidemiol       Date:  1999-08-01       Impact factor: 4.897

7.  The use of rectal douches among HIV-uninfected and infected men who have unprotected receptive anal intercourse: implications for rectal microbicides.

Authors:  Alex Carballo-Diéguez; José A Bauermeister; Ana Ventuneac; Curtis Dolezal; Ivan Balan; Robert H Remien
Journal:  AIDS Behav       Date:  2007-08-18

8.  Sexual diversity, social inclusion and HIV/AIDS.

Authors:  Carlos F Cáceres; Peter Aggleton; Jerome T Galea
Journal:  AIDS       Date:  2008-08       Impact factor: 4.177

9.  Preference for gel over suppository as delivery vehicle for a rectal microbicide: results of a randomised, crossover acceptability trial among men who have sex with men.

Authors:  A Carballo-Diéguez; C Dolezal; J A Bauermeister; W O'Brien; A Ventuneac; K Mayer
Journal:  Sex Transm Infect       Date:  2008-11       Impact factor: 3.519

Review 10.  Elevated risk for HIV infection among men who have sex with men in low- and middle-income countries 2000-2006: a systematic review.

Authors:  Stefan Baral; Frangiscos Sifakis; Farley Cleghorn; Chris Beyrer
Journal:  PLoS Med       Date:  2007-12       Impact factor: 11.069

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  4 in total

1.  Preference of Oral Tenofovir Disoproxil Fumarate/Emtricitabine Versus Rectal Tenofovir Reduced-Glycerin 1% Gel Regimens for HIV Prevention Among Cisgender Men and Transgender Women Who Engage in Receptive Anal Intercourse with Men.

Authors:  Alex Carballo-Diéguez; Rebecca Giguere; Curtis Dolezal; Cheng-Shiun Leu; Iván C Balán; William Brown; Christine Rael; Barbra A Richardson; Jeanna M Piper; Linda-Gail Bekker; Suwat Chariyalertsak; Anupong Chitwarakorn; Pedro Gonzales; Timothy H Holtz; Albert Liu; Kenneth H Mayer; Carmen D Zorrilla; Javier R Lama; Ian McGowan; Ross D Cranston
Journal:  AIDS Behav       Date:  2017-12

2.  HPV vaccine knowledge and acceptability among Peruvian men who have sex with men and transgender women: A pilot, qualitative study.

Authors:  Jerome T Galea; Emmi Monsour; César R Nureña; Magaly M Blas; Brandon Brown
Journal:  PLoS One       Date:  2017-02-28       Impact factor: 3.240

3.  Contexts of vulnerability and the acceptability of new biomedical HIV prevention technologies among key populations in South Africa: A qualitative study.

Authors:  Millicent Atujuna; Peter A Newman; Melissa Wallace; Megan Eluhu; Clara Rubincam; Ben Brown; Linda-Gail Bekker
Journal:  PLoS One       Date:  2018-02-08       Impact factor: 3.240

Review 4.  Nanoparticles as potential new generation broad spectrum antimicrobial agents.

Authors:  Clarence S Yah; Geoffrey S Simate
Journal:  Daru       Date:  2015-09-02       Impact factor: 3.117

  4 in total

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