Literature DB >> 24823343

Pain and the thermally injured patient-a review of current therapies.

Helene Retrouvey1, Shahriar Shahrokhi.   

Abstract

Thermally injured patients experience tremendous pain from the moment of injury to months or years after their discharge from the hospital. Pain is therefore a critical component of proper management of burns. Although the importance of pain is well recognized, it is often undertreated. Acute uncontrolled pain has been shown to increase the incidence of mental health disorders and increase the incidence of suicide after discharge. Long-term poor pain control leads to an increase in the incidence of persistent pain. Most burn centers have used opioids as the mainstay analgesic, but recently, the significant side effects of opioids have led to the implementation of new and combined therapeutics. Pharmacological agents such as gabapentin, clonidine, dexmedetomidine, and ketamine have all been suggested as adjuncts to opioids in the treatment of burn pain. Nonpharmacological therapies such as hypnosis, virtual reality devices, and behavioral therapy are also essential adjuncts to current medications. This review aims at identifying the currently available pharmacological and nonpharmacological options for optimal pain management in the adult burn population.

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Year:  2015        PMID: 24823343     DOI: 10.1097/BCR.0000000000000073

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  13 in total

1.  Perioperative Multimodal Analgesia Reduces Opioid Use Following Skin Grafting in Nonintubated Burn Patients.

Authors:  Richard Lennertz; Haley Zimmerman; Timothy McCormick; Scott Hetzel; Lee Faucher; Angela Gibson
Journal:  J Burn Care Res       Date:  2020-11-30       Impact factor: 1.845

2.  American Burn Association Guidelines on the Management of Acute Pain in the Adult Burn Patient: A Review of the Literature, a Compilation of Expert Opinion, and Next Steps.

Authors:  Kathleen S Romanowski; Joshua Carson; Kate Pape; Eileen Bernal; Sam Sharar; Shelley Wiechman; Damien Carter; Yuk Ming Liu; Stephanie Nitzschke; Paul Bhalla; Jeffrey Litt; Rene Przkora; Bruce Friedman; Stephanie Popiak; James Jeng; Colleen M Ryan; Victor Joe
Journal:  J Burn Care Res       Date:  2020-11-30       Impact factor: 1.845

3.  Multimodal Analgesia and Discharge Opioid Requirements in Burn Patients.

Authors:  Michael Wright; Jin A Lee
Journal:  J Burn Care Res       Date:  2020-09-23       Impact factor: 1.845

4.  Prescribing of Gabapentinoids with or without opioids after burn injury in the US, 2012-2018.

Authors:  Efstathia Polychronopoulou; Yong-Fang Kuo; Denise Wilkes; Mukaila A Raji
Journal:  Burns       Date:  2021-12-22       Impact factor: 2.744

Review 5.  To Treat or Not to Treat: The Effects of Pain on Experimental Parameters.

Authors:  Norman C Peterson; Elizabeth A Nunamaker; Patricia V Turner
Journal:  Comp Med       Date:  2017-12-01       Impact factor: 0.982

6.  Pain and itch outcome trajectories differ among European American and African American survivors of major thermal burn injury.

Authors:  Matthew C Mauck; Jennifer Smith; Jeffrey W Shupp; Mark A Weaver; Andrea Liu; Andrey V Bortsov; Bilal Lateef; Samuel W Jones; Felicia Williams; James Hwang; Rachel Karlnoski; David J Smith; Bruce A Cairns; Samuel A McLean
Journal:  Pain       Date:  2017-11       Impact factor: 7.926

7.  Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury.

Authors:  Dustin Green; Shivani Ruparel; Xiaoli Gao; Nikita Ruparel; Mayur Patil; Armen Akopian; Kenneth Hargreaves
Journal:  Mol Pain       Date:  2016-07-12       Impact factor: 3.395

8.  Dexmedetomidine: Current Role in Burn ICU.

Authors:  G Scibelli; L Maio; M Sasso; A Lanza; G Savoia
Journal:  Transl Med UniSa       Date:  2017-07-01

9.  Virtual restorative environment therapy as an adjunct to pain control during burn dressing changes: study protocol for a randomised controlled trial.

Authors:  Charlotte Small; Robert Stone; Jane Pilsbury; Michael Bowden; Julian Bion
Journal:  Trials       Date:  2015-08-05       Impact factor: 2.279

10.  Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target.

Authors:  Kathleen Yin; Jennifer R Deuis; Richard J Lewis; Irina Vetter
Journal:  Mol Pain       Date:  2016-08-28       Impact factor: 3.395

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