Literature DB >> 24820694

Identifying environmental antigens that activate myelin-specific T cells.

Brian D Stadinski1, Eric S Huseby2.   

Abstract

Human genetic and environmental factors underlie susceptibility to the T cell-mediated autoimmune disease, multiple sclerosis (MS). How the environment influences the pathogenesis of MS has been difficult to parse. A recent paper in Cell shows that environmental antigens that activate myelin-specific T cells can be identified with unprecedented accuracy.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2014        PMID： 24820694      PMCID： PMC4070430          DOI： 10.1016/j.it.2014.04.004

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  10 in total

Review 1.  beta-Cell death during progression to diabetes.

Authors:  D Mathis; L Vence; C Benoist
Journal:  Nature       Date:  2001-12-13       Impact factor: 49.962

Review 2.  Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands.

Authors:  Frances Crawford; Kimberly R Jordan; Brian Stadinski; Yibing Wang; Eric Huseby; Philippa Marrack; Jill E Slansky; John W Kappler
Journal:  Immunol Rev       Date:  2006-04       Impact factor: 12.988

3.  Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide.

Authors:  Eric S Huseby; Frances Crawford; Janice White; Philippa Marrack; John W Kappler
Journal:  Nat Immunol       Date:  2006-10-15       Impact factor: 25.606

Review 4.  How the TCR balances sensitivity and specificity for the recognition of self and pathogens.

Authors:  Gerald P Morris; Paul M Allen
Journal:  Nat Immunol       Date:  2012-01-19       Impact factor: 25.606

5.  Chromogranin A is an autoantigen in type 1 diabetes.

Authors:  Brian D Stadinski; Thomas Delong; Nichole Reisdorph; Richard Reisdorph; Roger L Powell; Michael Armstrong; Jon D Piganelli; Gene Barbour; Brenda Bradley; Frances Crawford; Philippa Marrack; Sushil K Mahata; John W Kappler; Kathryn Haskins
Journal:  Nat Immunol       Date:  2010-02-07       Impact factor: 25.606

6.  Molecular mimicry: its evolution from concept to mechanism as a cause of autoimmune diseases.

Authors:  Michael B A Oldstone
Journal:  Monoclon Antib Immunodiagn Immunother       Date:  2014-04-02

7.  Deconstructing the peptide-MHC specificity of T cell recognition.

Authors:  Michael E Birnbaum; Juan L Mendoza; Dhruv K Sethi; Shen Dong; Jacob Glanville; Jessica Dobbins; Engin Ozkan; Mark M Davis; Kai W Wucherpfennig; K Christopher Garcia
Journal:  Cell       Date:  2014-05-22       Impact factor: 41.582

8.  Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone.

Authors:  B Hemmer; B T Fleckenstein; M Vergelli; G Jung; H McFarland; R Martin; K H Wiesmüller
Journal:  J Exp Med       Date:  1997-05-05       Impact factor: 14.307

9.  Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones.

Authors:  K W Wucherpfennig; A Sette; S Southwood; C Oseroff; M Matsui; J L Strominger; D A Hafler
Journal:  J Exp Med       Date:  1994-01-01       Impact factor: 14.307

10.  Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein.

Authors:  K W Wucherpfennig; J L Strominger
Journal:  Cell       Date:  1995-03-10       Impact factor: 41.582
  10 in total
  1 in total

1.  Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease.

Authors:  Catherine J Reynolds; Malcolm J W Sim; Kathryn J Quigley; Daniel M Altmann; Rosemary J Boyton
Journal:  J Neuroinflammation       Date:  2015-05-13       Impact factor: 8.322
  1 in total

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