| Literature DB >> 24820087 |
Nicole Bohm1, Charles Makowski2, Mario Machado3, Adam Davie4, Nelson Seabrook4, Lee Wheless4, Benjamin Bevill5, Bradley Clark5, T Rogers Kyle6.
Abstract
A patient receiving daptomycin developed asymptomatic transaminitis and hyperbilirubinemia without concurrent multiorgan dysfunction or elevation of his creatinine kinase level. After ruling out other etiologies, the liver injury was attributed to daptomycin and was subsequently resolved. A single-center retrospective cohort analysis of baseline and follow-up liver function panels (n = 614) from all admissions from 2008 to 2013 during which daptomycin was administered did not reveal any other cases of probable or definite drug-induced liver injury associated with daptomycin.Entities:
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Year: 2014 PMID: 24820087 PMCID: PMC4136030 DOI: 10.1128/AAC.03157-14
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191