Literature DB >> 2481741

A randomized trial of cyclobenzaprine for the treatment of fibromyalgia.

L G Quimby1, G M Gratwick, C D Whitney, S R Block.   

Abstract

We attempted a randomized, double blind trial of placebo vs cyclobenzaprine (Flexeril) in 40 female patients with fibromyalgia from a private rheumatology practice in Maine. Patient reports and physician global assessments indicated that cyclobenzaprine was more effective than placebo in alleviating symptoms of fibromyalgia in a subgroup of patients. However, most patients in the study had more accurate perceptions of drug effects than had been predicted and were able to identify the test drug. How much this awareness contributed to the perceived effectiveness of cyclobenzaprine is unknown.

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Year:  1989        PMID: 2481741

Source DB:  PubMed          Journal:  J Rheumatol Suppl        ISSN: 0380-0903


  14 in total

1.  [Pharmacological treatment of fibromyalgia syndrome].

Authors:  C Sommer; W Häuser; M Berliner; W Brückle; S Ehlers; K Mönkemöller; B Moradi; F Petzke; N Uçeyler; R Wörz; E Winter; D O Nutzinger
Journal:  Schmerz       Date:  2008-06       Impact factor: 1.107

Review 2.  Fibromyalgia: Treating Pain in the Juvenile Patient.

Authors:  Sabrina Gmuca; David D Sherry
Journal:  Paediatr Drugs       Date:  2017-08       Impact factor: 3.022

Review 3.  Fibromyalgia: an age-old malady begging for respect.

Authors:  R Powers
Journal:  J Gen Intern Med       Date:  1993-02       Impact factor: 5.128

Review 4.  Alternatives to Opioids in the Pharmacologic Management of Chronic Pain Syndromes: A Narrative Review of Randomized, Controlled, and Blinded Clinical Trials.

Authors:  Andrea L Nicol; Robert W Hurley; Honorio T Benzon
Journal:  Anesth Analg       Date:  2017-11       Impact factor: 5.108

Review 5.  [Drug therapy of fibromyalgia syndrome. Systematic review, meta-analysis and guideline].

Authors:  C Sommer; W Häuser; R Alten; F Petzke; M Späth; T Tölle; N Uçeyler; A Winkelmann; E Winter; K J Bär
Journal:  Schmerz       Date:  2012-06       Impact factor: 1.107

Review 6.  Management of fibromyalgia: what are the best treatment choices?

Authors:  Karin Ø Forseth K; Jan T Gran
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 7.  Pharmaceutical treatment options for fibromyalgia.

Authors:  Leslie J Crofford
Journal:  Curr Rheumatol Rep       Date:  2004-08       Impact factor: 4.592

Review 8.  Management of fibromyalgia.

Authors:  Ashwin A Patkar; Louai Bilal; Prakash S Masand
Journal:  Curr Psychiatry Rep       Date:  2003-07       Impact factor: 5.285

Review 9.  Antidepressants for the treatment of chronic pain.

Authors:  Bénédicte Verdu; Isabelle Decosterd; Thierry Buclin; Friedrich Stiefel; Alexandre Berney
Journal:  Drugs       Date:  2008       Impact factor: 9.546

Review 10.  A practical approach to fibromyalgia.

Authors:  Tyler Childs Cymet
Journal:  J Natl Med Assoc       Date:  2003-04       Impact factor: 1.798

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