BACKGROUND: An interdisciplinary guideline for the treatment of fibromyalgia syndrome (FMS) and chronic widespread pain (CWP) was developed in cooperation with ten German medical and psychological associations and two patients' self-help organizations. METHODS: Using the Cochrane Collaboration Reviews (1993-12/2006), Medline (1980-2006), PsychInfo (1966-12/2006), and Scopus (1980-12/ 2006) a systematic literature search was performed, which included all randomised controlled trials (RCT) evaluating multicomponent therapy in FMS and CWP. Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. The strength of recommendation was graded according to the German program for disease management guidelines. Consensus was achieved using a multi-step nominal group procedure. RESULTS: The short-term use of amitriptyline is strongly recommended (grade A) and the short-term use of fluoxetine und duloxetine is recommended (grade B). CONCLUSIONS: The recommendations regarding pharmacological treatment of FMS are limited by the short duration of the RCT, the lack of follow-ups and absence of cost-effectiveness studies.
BACKGROUND: An interdisciplinary guideline for the treatment of fibromyalgia syndrome (FMS) and chronic widespread pain (CWP) was developed in cooperation with ten German medical and psychological associations and two patients' self-help organizations. METHODS: Using the Cochrane Collaboration Reviews (1993-12/2006), Medline (1980-2006), PsychInfo (1966-12/2006), and Scopus (1980-12/ 2006) a systematic literature search was performed, which included all randomised controlled trials (RCT) evaluating multicomponent therapy in FMS and CWP. Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. The strength of recommendation was graded according to the German program for disease management guidelines. Consensus was achieved using a multi-step nominal group procedure. RESULTS: The short-term use of amitriptyline is strongly recommended (grade A) and the short-term use of fluoxetine und duloxetine is recommended (grade B). CONCLUSIONS: The recommendations regarding pharmacological treatment of FMS are limited by the short duration of the RCT, the lack of follow-ups and absence of cost-effectiveness studies.
Authors: Lesley M Arnold; Amy Rosen; Yili Lu Pritchett; Deborah N D'Souza; David J Goldstein; Smriti Iyengar; Joachim F Wernicke Journal: Pain Date: 2005-11-17 Impact factor: 6.961
Authors: Lesley M Arnold; Evelyn V Hess; James I Hudson; Jeffrey A Welge; Sarah E Berno; Paul E Keck Journal: Am J Med Date: 2002-02-15 Impact factor: 4.965
Authors: C Sommer; W Häuser; R Alten; F Petzke; M Späth; T Tölle; N Uçeyler; A Winkelmann; E Winter; K J Bär Journal: Schmerz Date: 2012-06 Impact factor: 1.107
Authors: Winfried Häuser; Wolfgang Eich; Markus Herrmann; Detlev O Nutzinger; Marcus Schiltenwolf; Peter Henningsen Journal: Dtsch Arztebl Int Date: 2009-06-05 Impact factor: 5.594
Authors: Jason W Busse; Shanil Ebrahim; Gaelan Connell; Eric A Coomes; Paul Bruno; Keshena Malik; David Torrance; Trung Ngo; Karin Kirmayr; Daniel Avrahami; John J Riva; Peter Struijs; David Brunarski; Stephen J Burnie; Frances LeBlanc; Ivan A Steenstra; Quenby Mahood; Kristian Thorlund; Victor M Montori; Vishalini Sivarajah; Paul Alexander; Milosz Jankowski; Wiktoria Lesniak; Markus Faulhaber; Małgorzata M Bała; Stefan Schandelmaier; Gordon H Guyatt Journal: Syst Rev Date: 2013-03-13
Authors: Winfried Häuser; Bernhard Arnold; Wolfgang Eich; Eva Felde; Christl Flügge; Peter Henningsen; Markus Herrmann; Volker Köllner; Edeltraud Kühn; Detlev Nutzinger; Martin Offenbächer; Marcus Schiltenwolf; Claudia Sommer; Kati Thieme; Ina Kopp Journal: Ger Med Sci Date: 2008-12-09