Literature DB >> 24814673

A multifunctional enzyme is involved in bacterial ether lipid biosynthesis.

Wolfram Lorenzen1, Tilman Ahrendt1, Kenan A J Bozhüyük1, Helge B Bode1.   

Abstract

Fatty acid-derived ether lipids are present not only in most vertebrates but also in some bacteria. Here we describe what is to our knowledge the first gene cluster involved in the biosynthesis of such lipids in myxobacteria that encodes the multifunctional enzyme ElbD, which shows similarity to polyketide synthases. Initial characterization of elbD mutants in Myxococcus xanthus and Stigmatella aurantiaca showed the importance of these ether lipids for fruiting body formation and sporulation.

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Year:  2014        PMID： 24814673     DOI： 10.1038/nchembio.1526

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


  31 in total

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  12 in total

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9.  Dynamics of Microbial Communities in Phototrophic Polyhydroxyalkanoate Accumulating Cultures.

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10.  Anti-Idiotype Vaccine Provides Protective Immunity Against Vibrio Harveyi in Grouper (Epinephelus Coioides).

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