Literature DB >> 24807219

Translating glycolytic metabolism to innate immunity in dendritic cells.

Mario Cortese1, Charles Sinclair1, Bali Pulendran1.   

Abstract

Growing evidence supports a role for glycolysis in immune activation. Everts et al. (2014) now show that TLR-mediated stimulation of dendritic cells rapidly induces glycolysis, which regenerates NADPH and TCA intermediates to support fatty acid production. This enhances ER and Golgi membrane synthesis and innate activation of dendritic cells.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24807219      PMCID： PMC4050200          DOI： 10.1016/j.cmet.2014.04.012

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  9 in total

1.  Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.

Authors:  Bart Everts; Eyal Amiel; Gerritje J W van der Windt; Tori C Freitas; Robert Chott; Kevin E Yarasheski; Erika L Pearce; Edward J Pearce
Journal:  Blood       Date:  2012-07-11       Impact factor: 22.113

2.  Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation.

Authors:  Connie M Krawczyk; Thomas Holowka; Jie Sun; Julianna Blagih; Eyal Amiel; Ralph J DeBerardinis; Justin R Cross; Euihye Jung; Craig B Thompson; Russell G Jones; Edward J Pearce
Journal:  Blood       Date:  2010-03-29       Impact factor: 22.113

3.  TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.

Authors:  Bart Everts; Eyal Amiel; Stanley Ching-Cheng Huang; Amber M Smith; Chih-Hao Chang; Wing Y Lam; Veronika Redmann; Tori C Freitas; Julianna Blagih; Gerritje J W van der Windt; Maxim N Artyomov; Russell G Jones; Erika L Pearce; Edward J Pearce
Journal:  Nat Immunol       Date:  2014-02-23       Impact factor: 25.606

4.  Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation.

Authors:  Rajesh Ravindran; Nooruddin Khan; Helder I Nakaya; Shuzhao Li; Jens Loebbermann; Mohan S Maddur; Youngja Park; Dean P Jones; Pascal Chappert; Jean Davoust; David S Weiss; Herbert W Virgin; David Ron; Bali Pulendran
Journal:  Science       Date:  2013-12-05       Impact factor: 47.728

5.  Posttranscriptional control of T cell effector function by aerobic glycolysis.

Authors:  Chih-Hao Chang; Jonathan D Curtis; Leonard B Maggi; Brandon Faubert; Alejandro V Villarino; David O'Sullivan; Stanley Ching-Cheng Huang; Gerritje J W van der Windt; Julianna Blagih; Jing Qiu; Jason D Weber; Edward J Pearce; Russell G Jones; Erika L Pearce
Journal:  Cell       Date:  2013-06-06       Impact factor: 41.582

6.  Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

Authors:  G M Tannahill; A M Curtis; J Adamik; E M Palsson-McDermott; A F McGettrick; G Goel; C Frezza; N J Bernard; B Kelly; N H Foley; L Zheng; A Gardet; Z Tong; S S Jany; S C Corr; M Haneklaus; B E Caffrey; K Pierce; S Walmsley; F C Beasley; E Cummins; V Nizet; M Whyte; C T Taylor; H Lin; S L Masters; E Gottlieb; V P Kelly; C Clish; P E Auron; R J Xavier; L A J O'Neill
Journal:  Nature       Date:  2013-03-24       Impact factor: 49.962

7.  Hypoxia and hypoxia-inducible factor-1 alpha modulate lipopolysaccharide-induced dendritic cell activation and function.

Authors:  Jonathan Jantsch; Dipshikha Chakravortty; Nadine Turza; Alexander T Prechtel; Björn Buchholz; Roman G Gerlach; Melanie Volke; Joachim Gläsner; Christina Warnecke; Michael S Wiesener; Kai-Uwe Eckardt; Alexander Steinkasserer; Michael Hensel; Carsten Willam
Journal:  J Immunol       Date:  2008-04-01       Impact factor: 5.422

8.  Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

Authors:  S Miyamoto; A N Murphy; J H Brown
Journal:  Cell Death Differ       Date:  2007-12-07       Impact factor: 15.828

Review 9.  PI-3-K and AKT: Onto the mitochondria.

Authors:  Bangyan L Stiles
Journal:  Adv Drug Deliv Rev       Date:  2009-08-29       Impact factor: 15.470
  9 in total
  11 in total

Review 1.  Role of the Golgi Apparatus in the Blood-Brain Barrier: Golgi Protection May Be a Targeted Therapy for Neurological Diseases.

Authors:  Shuwen Deng; Hui Liu; Ke Qiu; Hong You; Qiang Lei; Wei Lu
Journal:  Mol Neurobiol       Date:  2017-07-20       Impact factor: 5.590

2.  Regulation of endothelial cell metabolism: just go with the flow.

Authors:  Xinghui Sun; Mark W Feinberg
Journal:  Arterioscler Thromb Vasc Biol       Date:  2015-01       Impact factor: 8.311

3.  5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis.

Authors:  Ajay Kumar; Shailendra Giri; Ashok Kumar
Journal:  Cell Microbiol       Date:  2016-07-26       Impact factor: 3.715

4.  Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.

Authors:  Xiaodi Su; Yingpu Yu; Yi Zhong; Eugenia G Giannopoulou; Xiaoyu Hu; Hui Liu; Justin R Cross; Gunnar Rätsch; Charles M Rice; Lionel B Ivashkiv
Journal:  Nat Immunol       Date:  2015-06-29       Impact factor: 25.606

5.  TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection.

Authors:  Laure Perrin-Cocon; Anne Aublin-Gex; Stefania E Sestito; Kari Ann Shirey; Mira C Patel; Patrice André; Jorge C Blanco; Stefanie N Vogel; Francesco Peri; Vincent Lotteau
Journal:  Sci Rep       Date:  2017-01-20       Impact factor: 4.379

6.  The Antagonistic Effect of Mycotoxins Deoxynivalenol and Zearalenone on Metabolic Profiling in Serum and Liver of Mice.

Authors:  Jian Ji; Pei Zhu; Fangchao Cui; Fuwei Pi; Yinzhi Zhang; Yun Li; Jiasheng Wang; Xiulan Sun
Journal:  Toxins (Basel)       Date:  2017-01-10       Impact factor: 4.546

7.  Melatonin improves neurological outcomes and preserves hippocampal mitochondrial function in a rat model of cardiac arrest.

Authors:  Linghui Yang; Jing Wang; Yan Deng; Cansheng Gong; Qin Li; Qiu Chen; Huan Li; Chunling Jiang; Ronghua Zhou; Kerong Hai; Wei Wu; Tao Li
Journal:  PLoS One       Date:  2018-11-06       Impact factor: 3.240

Review 8.  Tricarboxylic Acid (TCA) Cycle Intermediates: Regulators of Immune Responses.

Authors:  Inseok Choi; Hyewon Son; Jea-Hyun Baek
Journal:  Life (Basel)       Date:  2021-01-19

9.  Autophagic protein ATG5 controls antiviral immunity via glycolytic reprogramming of dendritic cells against respiratory syncytial virus infection.

Authors:  Dong Sun Oh; Jang Hyun Park; Hi Eun Jung; Hyun-Jin Kim; Heung Kyu Lee
Journal:  Autophagy       Date:  2020-08-28       Impact factor: 16.016

10.  The effect of hydroalcoholic extract of Teucrium polium L. on the inflammatory markers and lipid profile in hypercholesterolemic rats.

Authors:  Mansour Amraei; Ayub Ghorbani; Ehsan Shirzadpour; Yaser Seifinejad; Seyedeh Fatemeh Mousavi; Mahmoud Mohamadpour
Journal:  J Inflamm Res       Date:  2018-06-18
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