| Literature DB >> 24802167 |
Alex Sawatzky, Qiaofeng Xu, Carsten O Schirra, Mark A Anastasio.
Abstract
The development of spectral X-ray computed tomography (CT) using binned photon-counting detectors has received great attention in recent years and has enabled selective imaging of contrast agents loaded with K-edge materials. A practical issue in implementing this technique is the mitigation of the high-noise levels often present in material-decomposed sinogram data. In this work, the spectral X-ray CT reconstruction problem is formulated within a multi-channel (MC) framework in which statistical correlations between the decomposed material sinograms can be exploited to improve image quality. Specifically, a MC penalized weighted least squares (PWLS) estimator is formulated in which the data fidelity term is weighted by the MC covariance matrix and sparsity-promoting penalties are employed. This allows the use of any number of basis materials and is therefore applicable to photon-counting systems and K-edge imaging. To overcome numerical challenges associated with use of the full covariance matrix as a data fidelity weight, a proximal variant of the alternating direction method of multipliers is employed to minimize the MC PWLS objective function. Computer-simulation and experimental phantom studies are conducted to quantitatively evaluate the proposed reconstruction method.Mesh:
Year: 2014 PMID: 24802167 DOI: 10.1109/TMI.2014.2321098
Source DB: PubMed Journal: IEEE Trans Med Imaging ISSN: 0278-0062 Impact factor: 10.048