Literature DB >> 24801170

Emerging insights into the role of microRNAs in the pathogenesis of cholangiocarcinoma.

Hiroaki Haga1, Irene Yan, Kenji Takahashi, Joseph Wood, Tushar Patel.   

Abstract

The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.

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Year:  2014        PMID: 24801170      PMCID: PMC4166576          DOI: 10.3727/105221614X13919976902174

Source DB:  PubMed          Journal:  Gene Expr        ISSN: 1052-2166


  47 in total

1.  Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis.

Authors:  P Chusorn; N Namwat; W Loilome; A Techasen; C Pairojkul; N Khuntikeo; A Dechakhamphu; C Talabnin; W Chan-On; C K Ong; B T Teh; P Yongvanit
Journal:  Tumour Biol       Date:  2013-02-17

2.  MicroRNA-21 regulates the invasion and metastasis in cholangiocarcinoma and may be a potential biomarker for cancer prognosis.

Authors:  Qiang Huang; Lei Liu; Chen-Hai Liu; Hao You; Feng Shao; Fang Xie; Xian-Sheng Lin; San-Yuan Hu; Chuan-Hai Zhang
Journal:  Asian Pac J Cancer Prev       Date:  2013

3.  miR-373 negatively regulates methyl-CpG-binding domain protein 2 (MBD2) in hilar cholangiocarcinoma.

Authors:  Yongjun Chen; Jian Luo; Rui Tian; Huawen Sun; Shengquan Zou
Journal:  Dig Dis Sci       Date:  2010-11-18       Impact factor: 3.199

4.  MicroRNA-26a promotes cholangiocarcinoma growth by activating β-catenin.

Authors:  Jinqiang Zhang; Chang Han; Tong Wu
Journal:  Gastroenterology       Date:  2012-04-03       Impact factor: 22.682

5.  The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma.

Authors:  Lei Chen; He-Xin Yan; Wen Yang; Liang Hu; Le-Xin Yu; Qiong Liu; Liang Li; Dan-Dan Huang; Jin Ding; Feng Shen; Wei-Ping Zhou; Meng-Chao Wu; Hong-Yang Wang
Journal:  J Hepatol       Date:  2008-11-21       Impact factor: 25.083

6.  MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.

Authors:  Florin M Selaru; Alexandru V Olaru; Takatsugu Kan; Stefan David; Yulan Cheng; Yuriko Mori; Jian Yang; Bogdan Paun; Zhe Jin; Rachana Agarwal; James P Hamilton; John Abraham; Christos Georgiades; Hector Alvarez; Perumal Vivekanandan; Wayne Yu; Anirban Maitra; Michael Torbenson; Paul J Thuluvath; Gregory J Gores; Nicholas F LaRusso; Ralph Hruban; Stephen J Meltzer
Journal:  Hepatology       Date:  2009-05       Impact factor: 17.425

7.  Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.

Authors:  George Adrian Calin; Cinzia Sevignani; Calin Dan Dumitru; Terry Hyslop; Evan Noch; Sai Yendamuri; Masayoshi Shimizu; Sashi Rattan; Florencia Bullrich; Massimo Negrini; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-18       Impact factor: 11.205

8.  Expression profiles of oncomir miR-21 and tumor suppressor let-7a in the progression of opisthorchiasis-associated cholangiocarcinoma.

Authors:  N Namwat; P Chusorn; W Loilome; A Techasen; J Puetkasichonpasutha; C Pairojkul; N Khuntikeo; P Yongvanit
Journal:  Asian Pac J Cancer Prev       Date:  2012

9.  MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell line.

Authors:  Jun Iwaki; Kunio Kikuchi; Yoshiaki Mizuguchi; Yutaka Kawahigashi; Hiroshi Yoshida; Eiji Uchida; Toshihiro Takizawa
Journal:  PLoS One       Date:  2013-07-26       Impact factor: 3.240

10.  Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis.

Authors:  F Peng; J Jiang; Y Yu; R Tian; X Guo; X Li; M Shen; M Xu; F Zhu; C Shi; J Hu; M Wang; R Qin
Journal:  Br J Cancer       Date:  2013-10-29       Impact factor: 7.640

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  13 in total

Review 1.  MicroRNAs and benign biliary tract diseases.

Authors:  Sergio A Gradilone; Steven P O'Hara; Tetyana V Masyuk; Maria Jose Lorenzo Pisarello; Nicholas F LaRusso
Journal:  Semin Liver Dis       Date:  2015-01-29       Impact factor: 6.115

Review 2.  The role of miRNAs in cholangiocarcinoma.

Authors:  Jessica A Howell; Shahid A Khan
Journal:  Hepat Oncol       Date:  2016-03-29

3.  LncRNA PCAT6 increased cholangiocarcinoma cell proliferation and invasion via modulating miR-330-5p.

Authors:  Yongjie Xin; Xu He; Wei Zhao; Meixiao Zhan; Yong Li; Jing Xiao; Ke He; Ligong Lu
Journal:  Am J Transl Res       Date:  2019-09-15       Impact factor: 4.060

4.  Reduced atherosclerosis lesion size, inflammatory response in miR-150 knockout mice via macrophage effects.

Authors:  Fu-Han Gong; Wen-Lin Cheng; Haiping Wang; Maomao Gao; Juan-Juan Qin; Yan Zhang; Xia Li; Xueyong Zhu; Hao Xia; Zhi-Gang She
Journal:  J Lipid Res       Date:  2018-02-20       Impact factor: 5.922

5.  Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma.

Authors:  Benjamin Goeppert; Christina Ernst; Constance Baer; Stephanie Roessler; Marcus Renner; Arianeb Mehrabi; Mohammadreza Hafezi; Anita Pathil; Arne Warth; Albrecht Stenzinger; Wilko Weichert; Marion Bähr; Rainer Will; Peter Schirmacher; Christoph Plass; Dieter Weichenhan
Journal:  Epigenetics       Date:  2016-09-03       Impact factor: 4.528

6.  Downregulation of miR-145 alleviates ox-LDL-induced inflammation by targeting QKI in macrophages.

Authors:  Xueqiang Feng; Fuwang Yao; Yuqin Lang; Zhibin Cao
Journal:  Am J Transl Res       Date:  2022-06-15       Impact factor: 3.940

7.  MicroRNA-26b-5p regulates cell proliferation, invasion and metastasis in human intrahepatic cholangiocarcinoma by targeting S100A7.

Authors:  Fei Fan; Jiongjiong Lu; Wenlong Yu; Yongjie Zhang; Suqian Xu; Leilei Pang; Bin Zhu
Journal:  Oncol Lett       Date:  2017-11-02       Impact factor: 2.967

8.  A functional microRNA library screen reveals miR-410 as a novel anti-apoptotic regulator of cholangiocarcinoma.

Authors:  Tiziana Palumbo; George A Poultsides; Grigorios Kouraklis; Theodore Liakakos; Alexandra Drakaki; George Peros; Maria Hatziapostolou; Dimitrios Iliopoulos
Journal:  BMC Cancer       Date:  2016-06-03       Impact factor: 4.430

Review 9.  Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers.

Authors:  Pablo Letelier; Ismael Riquelme; Alfonso H Hernández; Neftalí Guzmán; Jorge G Farías; Juan Carlos Roa
Journal:  Int J Mol Sci       Date:  2016-05-23       Impact factor: 5.923

Review 10.  MicroRNAs in the Cholangiopathies: Pathogenesis, Diagnosis, and Treatment.

Authors:  Maria Jose Lorenzo Pisarello; Lorena Loarca; Tommy Ivanics; Leslie Morton; Nicholas LaRusso
Journal:  J Clin Med       Date:  2015-08-26       Impact factor: 4.241

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