| Literature DB >> 24795111 |
Kristen K Miller1, Loren Gorcey1, Beth N McLellan2.
Abstract
Chemotherapy-induced hand-foot syndrome and nail changes are common complications of many classic chemotherapeutic agents and the newer molecular targeted therapies. They significantly impact patient quality of life, and frequently necessitate chemotherapy dose intensity modification or reduction. We aim to describe the epidemiology, pathogenesis, clinical presentation, and current evidence-based treatment options for these entities.Entities:
Keywords: chemotherapy complications; chemotherapy nail complications; hand-foot skin reaction; hand-foot syndrome; molecular targeted therapy complications; palmoplantar erythrodysesthesia
Mesh:
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Year: 2014 PMID: 24795111 DOI: 10.1016/j.jaad.2014.03.019
Source DB: PubMed Journal: J Am Acad Dermatol ISSN: 0190-9622 Impact factor: 11.527