Marina D M Lima1, Paulo Henrique Braz-Silva2, Sônia M Pereira3, Catalina Riera4, Ariane C Coelho5, Marina Gallottini6. 1. Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil; Department of Pathology and Clinical Dentistry, Federal University of Piauí, Teresina, Brazil. 2. Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil; Laboratory of Virology, Institute of Tropical Medicine, University of São Paulo, São Paulo, Brazil. 3. Division of Pathology, Adolfo Lutz Institute, São Paulo, Brazil. 4. Division of Dentistry, Center for Sexually Transmitted Diseases - CRT DST/AIDS-SP, São Paulo, Brazil. 5. Division of Gynecology, Center for Sexually Transmitted Diseases - CRT DST/AIDS-SP, São Paulo, Brazil. 6. Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil. Electronic address: mhcgmaga@usp.br.
Abstract
OBJECTIVE: To investigate the prevalence of HPV infections in the oral and cervical mucosa of HIV-positive and HIV-negative women attending a sexual health clinic. METHODS: One-hundred HIV-positive women and 100 HIV-negative women were recruited from a sexual health clinic in São Paulo, Brazil. All participants were given an oral and cervical examination. Cytologic samples were evaluated via HPV DNA test. RESULTS: In oral samples, HPV DNA was observed in 11 women from the HIV-positive group and 2 from the HIV-negative group. High-risk HPV subtypes were prevalent in both groups and no difference between groups was detected. HPV DNA was detected in cervical scrapings from 41 HIV-positive women and 45 HIV-negative women (P=0.67). No participants showed oral lesions, whereas 15 HIV-positive and 17 HIV-negative women presented with macroscopic genital lesions. CONCLUSION: HPV is detected more often in cervical scrapings than in oral samples. However, HPV oral shedding is more frequent in HIV-positive than in HIV-negative individuals. Concurrence of infection (high and low risk) was not observed in oral and cervical mucosa.
OBJECTIVE: To investigate the prevalence of HPV infections in the oral and cervical mucosa of HIV-positive and HIV-negative women attending a sexual health clinic. METHODS: One-hundred HIV-positive women and 100 HIV-negative women were recruited from a sexual health clinic in São Paulo, Brazil. All participants were given an oral and cervical examination. Cytologic samples were evaluated via HPV DNA test. RESULTS: In oral samples, HPV DNA was observed in 11 women from the HIV-positive group and 2 from the HIV-negative group. High-risk HPV subtypes were prevalent in both groups and no difference between groups was detected. HPV DNA was detected in cervical scrapings from 41 HIV-positive women and 45 HIV-negative women (P=0.67). No participants showed oral lesions, whereas 15 HIV-positive and 17 HIV-negative women presented with macroscopic genital lesions. CONCLUSION: HPV is detected more often in cervical scrapings than in oral samples. However, HPV oral shedding is more frequent in HIV-positive than in HIV-negative individuals. Concurrence of infection (high and low risk) was not observed in oral and cervical mucosa.
Authors: Juliana D Siqueira; Gislaine Curty; Deng Xutao; Cristina B Hofer; Elizabeth S Machado; Héctor N Seuánez; Marcelo A Soares; Eric Delwart; Esmeralda A Soares Journal: Viruses Date: 2019-05-07 Impact factor: 5.048
Authors: Milagros Pérez-Quintanilla; Rocío Méndez-Martínez; Salvador Vázquez-Vega; Raquel Espinosa-Romero; Rita Sotelo-Regil; María Delia Pérez-Montiel; Ubaldo Ramos-Alamillo; Teresita de Jesús Cabrera-López; Salim Abraham Barquet-Muñoz; Carlos Pérez-Plascencia; Alejandro García-Carrancá; David Cantú de León Journal: PLoS One Date: 2020-04-22 Impact factor: 3.240