Literature DB >> 24792226

Synthesis and crystal structure of new heterocycles containing 1,2,4-oxadiazole, 1,2,4-oxadiazolone (thione), hydantoin, and mercaptobenzimidazole units.

Yaşar Dürüst1, Özge Gözlükaya, Gülsün Özer, Frank R Fronczek.   

Abstract

A number of 1,2,4-oxadiazolone and mercapto nitro benzimidazole derivatives containing 1,2,4-oxadiazole and hydantoin moieties have been prepared, and their structures were identified by means of spectral/physical characteristics including X-ray diffraction data.

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Year:  2014        PMID: 24792226     DOI: 10.1007/s11030-014-9525-7

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  13 in total

1.  Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists.

Authors:  Marco Mor; Fabrizio Bordi; Claudia Silva; Silvia Rivara; Valentina Zuliani; Federica Vacondio; Mirko Rivara; Elisabetta Barocelli; Simona Bertoni; Vigilio Ballabeni; Francesca Magnanini; Mariannina Impicciatore; Pier Vincenzo Plazzi
Journal:  Bioorg Med Chem       Date:  2004-02-15       Impact factor: 3.641

2.  Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.

Authors:  Kande K D Amarasinghe; Artem G Evdokimov; Artem G Evidokimov; Kevin Xu; Cynthia M Clark; Matthew B Maier; Anil Srivastava; Anny-Odile Colson; Gina S Gerwe; George E Stake; Brian W Howard; Matthew E Pokross; Jeffrey L Gray; Kevin G Peters
Journal:  Bioorg Med Chem Lett       Date:  2006-06-12       Impact factor: 2.823

3.  Synthesis of 2-mercaptobenzimidazole derivatives as potential anti-microbial and cytotoxic agents.

Authors:  Kallappa M Hosamani; Ramya V Shingalapur
Journal:  Arch Pharm (Weinheim)       Date:  2011-01-31       Impact factor: 3.751

4.  Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors.

Authors:  L J Street; R Baker; T Book; C O Kneen; A M MacLeod; K J Merchant; G A Showell; J Saunders; R H Herbert; S B Freedman
Journal:  J Med Chem       Date:  1990-10       Impact factor: 7.446

5.  Synthesis of 3-aryl-5-decapentyl-1,2,4-oxadiazoles possessing antiinflammatory and antitumor properties.

Authors:  Natércia M Miranda Bezerra; Shalom P De Oliveira; Rajendra M Srivastava; Joel R Da Silva
Journal:  Farmaco       Date:  2005-10-20

6.  Synthesis and antimicrobial activity of substituted imidazolidinediones and thioxoimidazolidinones.

Authors:  J F Albuquerque; J A Rocha Filho; S S Brandao; M C Lima; E A Ximenes; S L Galdino; I R Pitta; J Chantegrel; M Perrissin; C Luu-Duc
Journal:  Farmaco       Date:  1999 Jan-Feb

7.  Novel benzodiazepine receptor partial agonists: oxadiazolylimidazobenzodiazepines.

Authors:  F Watjen; R Baker; M Engelstoff; R Herbert; A MacLeod; A Knight; K Merchant; J Moseley; J Saunders; C J Swain
Journal:  J Med Chem       Date:  1989-10       Impact factor: 7.446

8.  Oxadiazoles as ester bioisosteric replacements in compounds related to disoxaril. Antirhinovirus activity.

Authors:  G D Diana; D L Volkots; T J Nitz; T R Bailey; M A Long; N Vescio; S Aldous; D C Pevear; F J Dutko
Journal:  J Med Chem       Date:  1994-07-22       Impact factor: 7.446

9.  Comparison of azabicyclic esters and oxadiazoles as ligands for the muscarinic receptor.

Authors:  B S Orlek; F E Blaney; F Brown; M S Clark; M S Hadley; J Hatcher; G J Riley; H E Rosenberg; H J Wadsworth; P Wyman
Journal:  J Med Chem       Date:  1991-09       Impact factor: 7.446

10.  Novel thiazolidine-2,4-dione-4-thiosemicarbazone and 4-[(3,4-diaryl-3H-thiazol-2-yl)azo]thiazolidin-2-one derivatives: synthesis and evaluation for antimicrobial and anticancer properties.

Authors:  A Mohsen; M E Omar; H M Salama; N H Eshba
Journal:  Farmaco Sci       Date:  1985-01
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