M Méan1, A Limacher, S R Kahn, D Aujesky. 1. Division of General Internal Medicine, Department of General Internal Medicine, Bern University Hospital, Inselspital, 3010, Bern, Switzerland, marie.mean@insel.ch.
Abstract
PURPOSE: To prospectively evaluate the psychometric properties of the Venous Insufficiency Epidemiological and Economic Study (VEINES-QOL/Sym) questionnaire, an instrument to measure disease-specific quality of life and symptoms in elderly patients with deep vein thrombosis (DVT), and to validate a German version of the questionnaire. METHODS: In a prospective multicenter cohort study of patients aged ≥ 65 years with acute venous thromboembolism, we used standard psychometric tests and criteria to evaluate the reliability, validity, and responsiveness of the VEINES-QOL/Sym in patients with acute symptomatic DVT. We also performed an exploratory factor analysis. RESULTS: Overall, 352 French- and German-speaking patients were enrolled (response rate of 87 %). Both language versions of the VEINES-QOL/Sym showed good acceptability (missing data, floor and ceiling effects), reliability (internal consistency, item-total and inter-item correlations), validity (convergent, discriminant, known-groups differences), and responsiveness to clinical change over time in elderly patients with DVT. The exploratory factor analysis of the VEINES-QOL/Sym suggested three underlying dimensions: limitations in daily activities, DVT-related symptoms, and psychological impact. CONCLUSIONS: The VEINES-QOL/Sym questionnaire is a practical, reliable, valid, and responsive instrument to measure quality of life and symptoms in elderly patients with DVT and can be used with confidence in prospective studies to measure outcomes in such patients.
PURPOSE: To prospectively evaluate the psychometric properties of the Venous Insufficiency Epidemiological and Economic Study (VEINES-QOL/Sym) questionnaire, an instrument to measure disease-specific quality of life and symptoms in elderly patients with deep vein thrombosis (DVT), and to validate a German version of the questionnaire. METHODS: In a prospective multicenter cohort study of patients aged ≥ 65 years with acute venous thromboembolism, we used standard psychometric tests and criteria to evaluate the reliability, validity, and responsiveness of the VEINES-QOL/Sym in patients with acute symptomatic DVT. We also performed an exploratory factor analysis. RESULTS: Overall, 352 French- and German-speaking patients were enrolled (response rate of 87 %). Both language versions of the VEINES-QOL/Sym showed good acceptability (missing data, floor and ceiling effects), reliability (internal consistency, item-total and inter-item correlations), validity (convergent, discriminant, known-groups differences), and responsiveness to clinical change over time in elderly patients with DVT. The exploratory factor analysis of the VEINES-QOL/Sym suggested three underlying dimensions: limitations in daily activities, DVT-related symptoms, and psychological impact. CONCLUSIONS: The VEINES-QOL/Sym questionnaire is a practical, reliable, valid, and responsive instrument to measure quality of life and symptoms in elderly patients with DVT and can be used with confidence in prospective studies to measure outcomes in such patients.
Authors: Caroline B Terwee; Sandra D M Bot; Michael R de Boer; Daniëlle A W M van der Windt; Dirk L Knol; Joost Dekker; Lex M Bouter; Henrica C W de Vet Journal: J Clin Epidemiol Date: 2006-08-24 Impact factor: 6.437
Authors: A K Tuygun; B Ketenci; R Günay; A Görür; M R Güney; M Biçer; A Tuygun; B Ozay; S Cimen; M Demirtaş; I Yekeler Journal: J Cardiovasc Surg (Torino) Date: 2012-01-24 Impact factor: 1.888
Authors: Marion E T McMurdo; Helen Roberts; Stuart Parker; Nikki Wyatt; Helen May; Claire Goodman; Stephen Jackson; John Gladman; Sinead O'Mahony; Khalid Ali; Edward Dickinson; Paul Edison; Chris Dyer Journal: Age Ageing Date: 2011-09-11 Impact factor: 10.668
Authors: Susan R Kahn; Donna L Lamping; Thierry Ducruet; Louise Arsenault; Marie José Miron; André Roussin; Sylvie Desmarais; France Joyal; Jeannine Kassis; Susan Solymoss; Louis Desjardins; Mira Johri; Ian Shrier Journal: J Clin Epidemiol Date: 2006-06-23 Impact factor: 6.437
Authors: M M Koopman; P Prandoni; F Piovella; P A Ockelford; D P Brandjes; J van der Meer; A S Gallus; G Simonneau; C H Chesterman; M H Prins Journal: N Engl J Med Date: 1996-03-14 Impact factor: 91.245
Authors: Ewa Hedner; Jonas Carlsson; Károly R Kulich; Lennart Stigendal; Anders Ingelgård; Ingela Wiklund Journal: Health Qual Life Outcomes Date: 2004-06-23 Impact factor: 3.186
Authors: Suresh Vedantham; Susan R Kahn; Samuel Z Goldhaber; Anthony J Comerota; Sameer Parpia; Sreelatha Meleth; Diane Earp; Rick Williams; Akhilesh K Sista; William Marston; Suman Rathbun; Elizabeth A Magnuson; Mahmood K Razavi; Michael R Jaff; Clive Kearon Journal: Vasc Med Date: 2016-05-30 Impact factor: 3.239
Authors: Scott C Woller; Scott M Stevens; Stacy A Johnson; Joseph R Bledsoe; Brian Galovic; James F Lloyd; Emily L Wilson; Brent Armbruster; R Scott Evans Journal: Res Pract Thromb Haemost Date: 2019-05-13
Authors: Ingrid M Bistervels; Roisin Bavalia; Jan Beyer-Westendorf; Arina J Ten Cate-Hoek; Sebastian M Schellong; Michael J Kovacs; Nicolas Falvo; Karina Meijer; Dominique Stephan; Wim G Boersma; Marije Ten Wolde; Francis Couturaud; Peter Verhamme; Dominique Brisot; Susan R Kahn; Waleed Ghanima; Karine Montaclair; Amanda Hugman; Patrick Carroll; Gilles Pernod; Olivier Sanchez; Emile Ferrari; Pierre-Marie Roy; Marie-Antoinette Sevestre-Pietri; Simone Birocchi; Hilde S Wik; Barbara A Hutten; Michiel Coppens; Christiane Naue; Michael A Grosso; Minggao Shi; Yong Lin; Isabelle Quéré; Saskia Middeldorp Journal: Res Pract Thromb Haemost Date: 2022-07-01
Authors: Timme Maj van Vuuren; Jorinde H H van Laanen; Maaike de Geus; Patty J Nelemans; Rick de Graaf; Cees H A Wittens Journal: BMJ Open Date: 2017-09-11 Impact factor: 2.692
Authors: Sophie E R Horbach; Amber P M Rongen; Roy G Elbers; Chantal M A M van der Horst; Cecilia A C Prinsen; Phyllis I Spuls Journal: Qual Life Res Date: 2019-09-23 Impact factor: 4.147