Sawsan Al-Sinani1, Mohammed Al-Shafaee2, Ali Al-Mamari3, Nicolas Woodhouse4, Omayma El-Shafie3, Mohammed O Hassan5, Said Al-Yahyaee6, Sulayma Albarwani5, Deepali Jaju7, Khamis Al-Hashmi4, Mohammed Al-Abri7, Syed Rizvi2, Riad Bayoumi1. 1. Departments of Biochemistry, College of Medicine & Health Sciences, Sultan Qaboos University; 2. Family Medicine & Public Health, College of Medicine & Health Sciences, Sultan Qaboos University; 3. Departments of Medicine, Sultan Qaboos University Hospital, Muscat, Oman. 4. Medicine, College of Medicine & Health Sciences, Sultan Qaboos University; 5. Physiology, College of Medicine & Health Sciences, Sultan Qaboos University; 6. Genetics, College of Medicine & Health Sciences, Sultan Qaboos University; 7. Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman.
Abstract
OBJECTIVES: The aim of this study was to estimate the prevalence of impaired fasting glucose (IFG) among Omani adults with no family history (FH) of diabetes and to investigate the factors behind the risk of developing type 2 diabetes (T2D), while excluding a FH of diabetes. METHODS: A total of 1,182 Omani adults, aged ≥40 years, visited the Family Medicine & Community Health Clinic at Sultan Qaboos University Hospital, Oman, on days other than the Diabetes Clinic days, from July 2010 to July 2011. The subjects were interviewed and asked if they had T2D or a FH of T2D. RESULTS: Only 191 (16%) reported no personal history of T2D or FH of the disease. Of these, anthropometric and biochemical data was complete in 159 subjects. Of these a total of 42 (26%) had IFG according to the American Diabetes Association criteria. Body mass index, fasting insulin, haemoglobin A1C and blood pressure (BP), were significantly higher among individuals with IFG (P <0.01, P <0.05, P <0.01 and P <0.01, respectively). In addition, fasting insulin, BP and serum lipid profile were correlated with obesity indices (P <0.05). Obesity indices were strongly associated with the risk of IFG among Omanis, with waist circumference being the strongest predictor. CONCLUSION: Despite claiming no FH of diabetes, a large number of Omani adults in this study had a high risk of developing diabetes. This is possibly due to environmental factors and endogamy. The high prevalence of obesity combined with genetically susceptible individuals is a warning that diabetes could be a future epidemic in Oman.
OBJECTIVES: The aim of this study was to estimate the prevalence of impaired fasting glucose (IFG) among Omani adults with no family history (FH) of diabetes and to investigate the factors behind the risk of developing type 2 diabetes (T2D), while excluding a FH of diabetes. METHODS: A total of 1,182 Omani adults, aged ≥40 years, visited the Family Medicine & Community Health Clinic at Sultan Qaboos University Hospital, Oman, on days other than the Diabetes Clinic days, from July 2010 to July 2011. The subjects were interviewed and asked if they had T2D or a FH of T2D. RESULTS: Only 191 (16%) reported no personal history of T2D or FH of the disease. Of these, anthropometric and biochemical data was complete in 159 subjects. Of these a total of 42 (26%) had IFG according to the American Diabetes Association criteria. Body mass index, fasting insulin, haemoglobin A1C and blood pressure (BP), were significantly higher among individuals with IFG (P <0.01, P <0.05, P <0.01 and P <0.01, respectively). In addition, fasting insulin, BP and serum lipid profile were correlated with obesity indices (P <0.05). Obesity indices were strongly associated with the risk of IFG among Omanis, with waist circumference being the strongest predictor. CONCLUSION: Despite claiming no FH of diabetes, a large number of Omani adults in this study had a high risk of developing diabetes. This is possibly due to environmental factors and endogamy. The high prevalence of obesity combined with genetically susceptible individuals is a warning that diabetes could be a future epidemic in Oman.
Entities:
Keywords:
Diabetes Mellitus, Type 2; Obesity; Oman; Prediabetic State; Prevalence
Authors: R A Scott; C Langenberg; S J Sharp; P W Franks; O Rolandsson; D Drogan; Y T van der Schouw; U Ekelund; N D Kerrison; E Ardanaz; L Arriola; B Balkau; A Barricarte; I Barroso; B Bendinelli; J W J Beulens; H Boeing; B de Lauzon-Guillain; P Deloukas; G Fagherazzi; C Gonzalez; S J Griffin; L C Groop; J Halkjaer; J M Huerta; R Kaaks; K T Khaw; V Krogh; P M Nilsson; T Norat; K Overvad; S Panico; L Rodriguez-Suarez; D Romaguera; I Romieu; C Sacerdote; M J Sánchez; A M W Spijkerman; B Teucher; A Tjonneland; R Tumino; D L van der A; P A Wark; M I McCarthy; E Riboli; N J Wareham Journal: Diabetologia Date: 2012-09-28 Impact factor: 10.122
Authors: Mohammed A Al-Abri; Deepali Jaju; Sawsan Al-Sinani; Ali Al-Mamari; Sulayma Albarwani; Khalid Al-Resadi; Riyadh Bayoumi; Mohammed Hassan; Khamis Al-Hashmi Journal: Oman Med J Date: 2016-11
Authors: Sithara Suresh; Mostafa Ibrahim Waly; Mohammad Shafiur Rahman; Nejib Guizani; Mohamed Abdullah Badar Al-Kindi; Halima Khalfan Ahmed Al-Issaei; Sultan Nasser Mohd Al-Maskari; Bader Rashid Said Al-Ruqaishi; Ahmed Al-Salami Journal: Prev Nutr Food Sci Date: 2017-12-31