Literature DB >> 24789197

Viral load detection using dried blood spots in a cohort of HIV-1-infected children in Uganda: correlations with clinical and immunological criteria for treatment failure.

Paola Costenaro1, Rebecca Lundin2, Maria Raffaella Petrara3, Martina Penazzato2, William Massavon2, Susan Kizito4, Sandra Monica Nabachwa4, Maria Nannyonga Musoke4, Charles Namisi4, Erika Morelli2, Davide Bilardi2, Antonio Mazza5, Marisa Zanchetta3, Carlo Giaquinto2, Anita De Rossi6.   

Abstract

Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of <1,000, 1,000 to 5,000, and >5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24789197      PMCID： PMC4097737          DOI： 10.1128/JCM.00961-14

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  12 in total

1.  Evaluation of in-house genotyping assay performance using dried blood spot specimens in the Global World Health Organization laboratory network.

Authors:  Neil Parkin; Carmen de Mendoza; Rob Schuurman; Cheryl Jennings; James Bremer; Michael R Jordan; Silvia Bertagnolio
Journal:  Clin Infect Dis       Date:  2012-05       Impact factor: 9.079

Review 2.  Dried blood spots for HIV-1 drug resistance and viral load testing: A review of current knowledge and WHO efforts for global HIV drug resistance surveillance.

Authors:  Silvia Bertagnolio; Neil T Parkin; Michael Jordan; James Brooks; J Gerardo García-Lerma
Journal:  AIDS Rev       Date:  2010 Oct-Dec       Impact factor: 2.500

3.  Prediction of treatment failure using 2010 World Health Organization Guidelines is associated with high misclassification rates and drug resistance among HIV-infected Cambodian children.

Authors:  Benjamin P Westley; Allison K DeLong; Chhraing S Tray; Dim Sophearin; Elizabeth M Dufort; Eric Nerrienet; Leeann Schreier; Joseph I Harwell; Rami Kantor
Journal:  Clin Infect Dis       Date:  2012-04-26       Impact factor: 9.079

4.  Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials.

Authors:  Angela M Mexas; Erin H Graf; Matthew J Pace; Jianqing J Yu; Emmanouil Papasavvas; Livio Azzoni; Michael P Busch; Michele Di Mascio; Andrea S Foulkes; Stephen A Migueles; Luis J Montaner; Una O'Doherty
Journal:  AIDS       Date:  2012-11-28       Impact factor: 4.177

5.  Comparison of HIV-1 RNA measurements obtained by using plasma and dried blood spots in the automated abbott real-time viral load assay.

Authors:  Miguel Arredondo; Carolina Garrido; Neil Parkin; Natalia Zahonero; Silvia Bertagnolio; Vincent Soriano; Carmen de Mendoza
Journal:  J Clin Microbiol       Date:  2011-12-14       Impact factor: 5.948

6.  Epstein-Barr virus load in children infected with human immunodeficiency virus type 1 in Uganda.

Authors:  Maria Raffaella Petrara; Martina Penazzato; William Massavon; Sandra Nabachwa; Maria Nannyonga; Antonio Mazza; Ketty Gianesin; Paola Del Bianco; Rebecca Lundin; Colin Sumpter; Marisa Zanchetta; Carlo Giaquinto; Anita De Rossi
Journal:  J Infect Dis       Date:  2014-02-18       Impact factor: 5.226

7.  Failure of immunologic criteria to appropriately identify antiretroviral treatment failure in Uganda.

Authors:  Steven J Reynolds; Gertrude Nakigozi; Kevin Newell; Anthony Ndyanabo; Ronald Galiwongo; Iga Boaz; Thomas C Quinn; Ron Gray; Maria Wawer; David Serwadda
Journal:  AIDS       Date:  2009-03-27       Impact factor: 4.177

8.  Evaluation of different RNA extraction methods and storage conditions of dried plasma or blood spots for human immunodeficiency virus type 1 RNA quantification and PCR amplification for drug resistance testing.

Authors:  Marjorie Monleau; Céline Montavon; Christian Laurent; Michel Segondy; Brigitte Montes; Eric Delaporte; François Boillot; Martine Peeters
Journal:  J Clin Microbiol       Date:  2009-02-04       Impact factor: 5.948

9.  Long-term decay of the HIV-1 reservoir in HIV-1-infected children treated with highly active antiretroviral therapy.

Authors:  Marisa Zanchetta; Sarah Walker; Nicoletta Burighel; Domenico Bellanova; Osvalda Rampon; Carlo Giaquinto; Anita De Rossi
Journal:  J Infect Dis       Date:  2006-05-10       Impact factor: 5.226

Review 10.  Development of antiretroviral resistance in children with HIV in low- and middle-income countries.

Authors:  Felicity Fitzgerald; Martina Penazzato; Diana Gibb
Journal:  J Infect Dis       Date:  2013-06-15       Impact factor: 5.226
View more
  7 in total

1.  Estimation of HIV-1 DNA Level Interfering with Reliability of HIV-1 RNA Quantification Performed on Dried Blood Spots Collected from Successfully Treated Patients.

Authors:  Sylvie Zida; Edouard Tuaillon; Makoura Barro; Arnaud Kwimatouo Lekpa Franchard; Thérèse Kagoné; Boubacar Nacro; Abdoul Salam Ouedraogo; Karine Bolloré; Armen Sanosyan; Jean-Christophe Plantier; Nicolas Meda; Lassana Sangaré; Christine Rouzioux; François Rouet; Dramane Kania
Journal:  J Clin Microbiol       Date:  2016-03-23       Impact factor: 5.948

2.  Measures of viral load using Abbott RealTime HIV-1 Assay on venous and fingerstick dried blood spots from provider-collected specimens in Malawian District Hospitals.

Authors:  Sarah E Rutstein; Deborah Kamwendo; Lebah Lugali; Isaac Thengolose; Gerald Tegha; Susan A Fiscus; Julie A E Nelson; Mina C Hosseinipour; Abdoulaye Sarr; Sundeep Gupta; Frank Chimbwandira; Reuben Mwenda; Ronald Mataya
Journal:  J Clin Virol       Date:  2014-05-22       Impact factor: 3.168

3.  Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers.

Authors:  Laura Mercatali; Patrizia Serra; Giacomo Miserocchi; Chiara Spadazzi; Chiara Liverani; Alessandro De Vita; Giorgia Marisi; Alberto Bongiovanni; Federica Recine; Akwilina Pangan; Nestory Masalu; Toni Ibrahim; Dino Amadori
Journal:  J Vis Exp       Date:  2018-06-11       Impact factor: 1.355

4.  Routine viral load monitoring in HIV-infected infants and children in low- and middle-income countries: challenges and opportunities.

Authors:  Stephen M Arpadi; Stephanie Shiau; Eduarda Pimentel De Gusmao; Avy Violari
Journal:  J Int AIDS Soc       Date:  2017-11       Impact factor: 5.396

5.  Impact of monotherapy on HIV-1 reservoir, immune activation, and co-infection with Epstein-Barr virus.

Authors:  Maria Raffaella Petrara; Anna Maria Cattelan; Lolita Sasset; Riccardo Freguja; Francesco Carmona; Silvia Sanavia; Marisa Zanchetta; Paola Del Bianco; Anita De Rossi
Journal:  PLoS One       Date:  2017-09-19       Impact factor: 3.240

6.  HIV treatment outcomes following antiretroviral therapy initiation and monitoring: A workplace program in Papua, Indonesia.

Authors:  Yuriko Limmade; Liony Fransisca; Rodrigo Rodriguez-Fernandez; Michael J Bangs; Camilla Rothe
Journal:  PLoS One       Date:  2019-02-25       Impact factor: 3.240

7.  Long-term clinical, virological and immunological outcomes following planned treatment interruption in HIV-infected children.

Authors:  R Freguja; A Bamford; M Zanchetta; P Del Bianco; C Giaquinto; L Harper; A Dalzini; T R Cressey; A Compagnucci; Y Saidi; Y Riault; D Ford; D Gibb; N Klein; A De Rossi
Journal:  HIV Med       Date:  2020-10-29       Impact factor: 3.180
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.