Literature DB >> 24789159

Molar pregnancy after tubal ligation in a patient with neuroendocrine tumour: when a rare condition coincides with an unexpected diagnosis.

Afi Mansa Semenya1, Caroline Roberts, Anne Mounsey.   

Abstract

A 40-year-old woman with a history of bilateral tubal ligation and a recent diagnosis of metastatic neuroendocrine tumour in the liver presented with severe nausea, vomiting, diarrhoea and dehydration. She had an inconclusive urine pregnancy test in the emergency department that was followed by an extremely high serum β-human chorionic gonadotropin. Transvaginal ultrasound, MRI and subsequent pathology from a dilation and curettage (D&C) revealed that the patient had a complete molar pregnancy. This is a case of an unusual patient who reminds us that one person can have a rare diagnosis and an unexpected obstetrical outcome. We could find no evidence in the medical literature of a causal link between these two diagnoses but present this case report of a reproductive age woman with neuroendocrine tumour and complete molar pregnancy. This case also serves as an example of the phenomenon of the 'hook effect.'

Entities:  

Mesh:

Year:  2014        PMID: 24789159      PMCID: PMC4025384          DOI: 10.1136/bcr-2014-203588

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

Review 1.  Circulating biomarkers in gastroenteropancreatic neuroendocrine tumours.

Authors:  Kjell Oberg
Journal:  Endocr Relat Cancer       Date:  2011-10-17       Impact factor: 5.678

2.  Molar pregnancy with false negative urine hCG: the hook effect.

Authors:  Y P Pang; H Rajesh; L K Tan
Journal:  Singapore Med J       Date:  2010-03       Impact factor: 1.858

3.  Carcinoid tumors of the gastrointestinal tract: a 44-year experience.

Authors:  S Saha; S Hoda; R Godfrey; C Sutherland; K Raybon
Journal:  South Med J       Date:  1989-12       Impact factor: 0.954

4.  Epidemiology of neuroendocrine tumours.

Authors:  B G Taal; O Visser
Journal:  Neuroendocrinology       Date:  2004       Impact factor: 4.914

5.  Sterilization in the United States.

Authors:  Deborah Bartz; James A Greenberg
Journal:  Rev Obstet Gynecol       Date:  2008

Review 6.  Epidemiology and aetiology of gestational trophoblastic diseases.

Authors:  Andrea Altieri; Silvia Franceschi; Jacques Ferlay; Jennifer Smith; Carlo La Vecchia
Journal:  Lancet Oncol       Date:  2003-11       Impact factor: 41.316

7.  Motor dysfunction of the small bowel and colon in patients with the carcinoid syndrome and diarrhea.

Authors:  M R von der Ohe; M Camilleri; L K Kvols; G M Thomforde
Journal:  N Engl J Med       Date:  1993-10-07       Impact factor: 91.245

8.  Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study.

Authors:  Peter Schmid; Yutaka Nagai; Roshan Agarwal; Barry Hancock; Philip M Savage; Neil J Sebire; Iain Lindsay; Michael Wells; Rosemary A Fisher; Delia Short; Edward S Newlands; Manfred B Wischnewsky; Michael J Seckl
Journal:  Lancet       Date:  2009-06-22       Impact factor: 79.321

9.  Routine pre-evacuation ultrasound diagnosis of hydatidiform mole: experience of more than 1000 cases from a regional referral center.

Authors:  D J Fowler; I Lindsay; M J Seckl; N J Sebire
Journal:  Ultrasound Obstet Gynecol       Date:  2006-01       Impact factor: 7.299

10.  Alpha-fetoprotein and human chorionic gonadotrophin-beta as prognostic markers in neuroendocrine tumour patients.

Authors:  T Shah; R Srirajaskanthan; M Bhogal; C Toubanakis; T Meyer; A Noonan; C Witney-Smith; T Amin; P Bhogal; N Sivathasan; B Warner; D Hochhauser; M E Caplin
Journal:  Br J Cancer       Date:  2008-06-24       Impact factor: 7.640

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