Literature DB >> 24786066

Cell biology. Dysfunctional mechanosensing in aneurysms.

Jay D Humphrey1, Dianna M Milewicz, George Tellides, Martin A Schwartz.   

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Year:  2014        PMID: 24786066      PMCID: PMC4360903          DOI: 10.1126/science.1253026

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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  12 in total

1.  Vascular smooth muscle cells orchestrate the assembly of type I collagen via alpha2beta1 integrin, RhoA, and fibronectin polymerization.

Authors:  Shaohua Li; Caroline Van Den Diepstraten; Sudhir J D'Souza; Bosco M C Chan; J Geoffrey Pickering
Journal:  Am J Pathol       Date:  2003-09       Impact factor: 4.307

Review 2.  The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles.

Authors:  Patrick Lacolley; Véronique Regnault; Antonino Nicoletti; Zhenlin Li; Jean-Baptiste Michel
Journal:  Cardiovasc Res       Date:  2012-03-31       Impact factor: 10.787

Review 3.  Integrins and extracellular matrix in mechanotransduction.

Authors:  Martin Alexander Schwartz
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-11-17       Impact factor: 10.005

Review 4.  Arterial adaptations to chronic changes in haemodynamic function: coupling vasomotor tone to structural remodelling.

Authors:  Dorota Dajnowiec; B Lowell Langille
Journal:  Clin Sci (Lond)       Date:  2007-07       Impact factor: 6.124

Review 5.  Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels.

Authors:  J D Humphrey
Journal:  Cell Biochem Biophys       Date:  2007-10-24       Impact factor: 2.194

Review 6.  Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction.

Authors:  Dianna M Milewicz; Dong-Chuan Guo; Van Tran-Fadulu; Andrea L Lafont; Christina L Papke; Sakiko Inamoto; Carrie S Kwartler; Hariyadarshi Pannu
Journal:  Annu Rev Genomics Hum Genet       Date:  2008       Impact factor: 8.929

7.  Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

Authors:  Wei Li; Qingle Li; Yang Jiao; Lingfeng Qin; Rahmat Ali; Jing Zhou; Jacopo Ferruzzi; Richard W Kim; Arnar Geirsson; Harry C Dietz; Stefan Offermanns; Jay D Humphrey; George Tellides
Journal:  J Clin Invest       Date:  2014-01-09       Impact factor: 14.808

Review 8.  Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm.

Authors:  Amalia Forte; Alessandro Della Corte; Marisa De Feo; Flavio Cerasuolo; Marilena Cipollaro
Journal:  Cardiovasc Res       Date:  2010-07-08       Impact factor: 10.787

Review 9.  Balancing forces: architectural control of mechanotransduction.

Authors:  Christopher C DuFort; Matthew J Paszek; Valerie M Weaver
Journal:  Nat Rev Mol Cell Biol       Date:  2011-05       Impact factor: 94.444

10.  Aortic remodeling after transverse aortic constriction in mice is attenuated with AT1 receptor blockade.

Authors:  Shao-Qing Kuang; Liang Geng; Siddharth K Prakash; Jiu-Mei Cao; Steven Guo; Carlos Villamizar; Callie S Kwartler; Andrew M Peters; Allan R Brasier; Dianna M Milewicz
Journal:  Arterioscler Thromb Vasc Biol       Date:  2013-07-18       Impact factor: 8.311

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  57 in total

1.  Mechanobiological oscillators control lymph flow.

Authors:  Christian Kunert; James W Baish; Shan Liao; Timothy P Padera; Lance L Munn
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-17       Impact factor: 11.205

Review 2.  Genome-wide association studies of late-onset cardiovascular disease.

Authors:  J Gustav Smith; Christopher Newton-Cheh
Journal:  J Mol Cell Cardiol       Date:  2015-04-11       Impact factor: 5.000

3.  Differences in genetic signaling, and not mechanical properties of the wall, are linked to ascending aortic aneurysms in fibulin-4 knockout mice.

Authors:  Jungsil Kim; Jesse D Procknow; Hiromi Yanagisawa; Jessica E Wagenseil
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-05-01       Impact factor: 4.733

Review 4.  Genetics of Thoracic and Abdominal Aortic Diseases.

Authors:  Amélie Pinard; Gregory T Jones; Dianna M Milewicz
Journal:  Circ Res       Date:  2019-02-15       Impact factor: 17.367

5.  Computational modelling suggests good, bad and ugly roles of glycosaminoglycans in arterial wall mechanics and mechanobiology.

Authors:  S Roccabianca; C Bellini; J D Humphrey
Journal:  J R Soc Interface       Date:  2014-08-06       Impact factor: 4.118

6.  mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice.

Authors:  Yang Jiao; Guangxin Li; Qingle Li; Rahmat Ali; Lingfeng Qin; Wei Li; Yibing Qyang; Daniel M Greif; Arnar Geirsson; Jay D Humphrey; George Tellides
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-07-27       Impact factor: 8.311

Review 7.  FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders.

Authors:  Lynn Y Sakai; Douglas R Keene; Marjolijn Renard; Julie De Backer
Journal:  Gene       Date:  2016-07-18       Impact factor: 3.688

Review 8.  Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models.

Authors:  Dianna M Milewicz; Siddharth K Prakash; Francesco Ramirez
Journal:  Annu Rev Med       Date:  2017-01-14       Impact factor: 13.739

9.  An iPSC-derived vascular model of Marfan syndrome identifies key mediators of smooth muscle cell death.

Authors:  Alessandra Granata; Felipe Serrano; William George Bernard; Madeline McNamara; Lucinda Low; Priya Sastry; Sanjay Sinha
Journal:  Nat Genet       Date:  2016-11-28       Impact factor: 38.330

10.  LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.

Authors:  Dianaly T Au; Zhekang Ying; Erick O Hernández-Ochoa; William E Fondrie; Brian Hampton; Mary Migliorini; Rebeca Galisteo; Martin F Schneider; Alan Daugherty; Debra L Rateri; Dudley K Strickland; Selen C Muratoglu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-11       Impact factor: 8.311

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