Literature DB >> 2478145

Inflammatory and immunomodulatory roles of TGF-beta.

S M Wahl, N McCartney-Francis, S E Mergenhagen.   

Abstract

Transforming growth factors (TGFs) are small polypeptides that were initially defined by their ability to induce transformation of non-neoplastic cells in culture. However, it has become increasingly clear that TGFs are not restricted in function to promoting cell growth. One type of transforming growth factor, TGF-beta, is a multifunctional molecule which has unique and potent effects on many target cells and tissues. In this article, Sharon Wahl, Nancy McCartney-Francis and Stephan Mergenhagen focus on the evolving role of TGF-beta in regulating inflammation, immune responses and tissue repair.

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Year:  1989        PMID： 2478145     DOI： 10.1016/0167-5699(89)90136-9

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  86 in total

1.  The regulation of prostaglandin output from term intact fetal membranes by anti-inflammatory cytokines.

Authors:  N L Brown; S A Alvi; M G Elder; P R Bennett; M H Sullivan
Journal:  Immunology       Date:  2000-01       Impact factor: 7.397

2.  Cellular responses to human chondrocytes: absence of allogeneic responses in the presence of HLA-DR and ICAM-1.

Authors:  P Jobanputra; V Corrigall; G Kingsley; G Panayi
Journal:  Clin Exp Immunol       Date:  1992-11       Impact factor: 4.330

3.  Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients.

Authors:  H Fukaura; S C Kent; M J Pietrusewicz; S J Khoury; H L Weiner; D A Hafler
Journal:  J Clin Invest       Date:  1996-07-01       Impact factor: 14.808

Review 4.  Tubular and interstitial factors in the progression of glomerulonephritis.

Authors:  J S Cameron
Journal:  Pediatr Nephrol       Date:  1992-05       Impact factor: 3.714

5.  Serum vascular endothelial growth factor, transforming growth factor β1, and nitric oxide levels in patients with psoriasis vulgaris: their correlation to disease severity.

Authors:  Abdel-Raheim M A Meki; Hani Al-Shobaili
Journal:  J Clin Lab Anal       Date:  2014-03-22       Impact factor: 2.352

Review 6.  The role of transforming growth factor-beta in inflammatory processes.

Authors:  S M Wahl
Journal:  Immunol Res       Date:  1991       Impact factor: 2.829

7.  Protection from interleukin 1 induced destruction of articular cartilage by transforming growth factor beta: studies in anatomically intact cartilage in vitro and in vivo.

Authors:  H M van Beuningen; P M van der Kraan; O J Arntz; W B van den Berg
Journal:  Ann Rheum Dis       Date:  1993-03       Impact factor: 19.103

8.  TGF-beta and IL-1 beta act in synergy to enhance IL-6 and IL-8 mRNA levels and IL-6 production by human retinal pigment epithelial cells.

Authors:  M C Kuppner; S McKillop-Smith; J V Forrester
Journal:  Immunology       Date:  1995-02       Impact factor: 7.397

9.  Interactions between interferon gamma and retinoic acid with transforming growth factor beta in the induction of immune recognition molecules.

Authors:  R Darley; A Morris; J Passas; W Bateman
Journal:  Cancer Immunol Immunother       Date:  1993-07       Impact factor: 6.968

10.  The release of transforming growth factor-beta following haemorrhage: its role as a mediator of host immunosuppression.

Authors:  A Ayala; D R Meldrum; M M Perrin; I H Chaudry
Journal:  Immunology       Date:  1993-07       Impact factor: 7.397
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