Literature DB >> 24776974

Prostate cancer: alcohol, cancer and 5α-reductase inhibitors-is there a link?

Leonard G Gomella1.   

Abstract

Two major trials have been performed to determine the effect of 5α-reductase inhibitors on subsequent diagnoses of prostate cancer. Both trials showed that high alcohol intake significantly increased prostate cancer risk among men allocated to the treatment arms. The recommendation that patients eliminate alcohol when taking 5α-reductase inhibitors seems appropriate.

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Year:  2014        PMID： 24776974     DOI： 10.1038/nrurol.2014.90

Source DB:  PubMed          Journal:  Nat Rev Urol        ISSN： 1759-4812            Impact factor:   14.432


  6 in total

1.  Effect of dutasteride on the risk of prostate cancer.

Authors:  Gerald L Andriole; David G Bostwick; Otis W Brawley; Leonard G Gomella; Michael Marberger; Francesco Montorsi; Curtis A Pettaway; Teuvo L Tammela; Claudio Teloken; Donald J Tindall; Matthew C Somerville; Timothy H Wilson; Ivy L Fowler; Roger S Rittmaster
Journal:  N Engl J Med       Date:  2010-04-01       Impact factor: 91.245

2.  Alcohol intake increases high-grade prostate cancer risk among men taking dutasteride in the REDUCE trial.

Authors:  Jay H Fowke; Lauren Howard; Gerald L Andriole; Stephen J Freedland
Journal:  Eur Urol       Date:  2014-02-09       Impact factor: 20.096

3.  Alcohol drinking and all cancer mortality: a meta-analysis.

Authors:  M Jin; S Cai; J Guo; Y Zhu; M Li; Y Yu; S Zhang; K Chen
Journal:  Ann Oncol       Date:  2012-10-26       Impact factor: 32.976

4.  The influence of finasteride on the development of prostate cancer.

Authors:  Ian M Thompson; Phyllis J Goodman; Catherine M Tangen; M Scott Lucia; Gary J Miller; Leslie G Ford; Michael M Lieber; R Duane Cespedes; James N Atkins; Scott M Lippman; Susie M Carlin; Anne Ryan; Connie M Szczepanek; John J Crowley; Charles A Coltman
Journal:  N Engl J Med       Date:  2003-06-24       Impact factor: 91.245

5.  Statin use and risk of prostate cancer and high-grade prostate cancer: results from the REDUCE study.

Authors:  S J Freedland; R J Hamilton; L Gerber; L L Banez; D M Moreira; G L Andriole; R S Rittmaster
Journal:  Prostate Cancer Prostatic Dis       Date:  2013-04-09       Impact factor: 5.554

6.  Alcohol consumption, finasteride, and prostate cancer risk: results from the Prostate Cancer Prevention Trial.

Authors:  Zhihong Gong; Alan R Kristal; Jeannette M Schenk; Catherine M Tangen; Phyllis J Goodman; Ian M Thompson
Journal:  Cancer       Date:  2009-08-15       Impact factor: 6.921
  6 in total

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