Francisco González-Vílchez1, Manuel Gómez-Bueno2, Luis Almenar3, María G Crespo-Leiro4, José M Arizón5, Manuel Martínez-Sellés6, Juan Delgado7, Eulalia Roig8, Ernesto Lage9, Nicolás Manito10. 1. Registro Español de Trasplante Cardiaco, Sección de Insuficiencia Cardiaca y Trasplante Cardiaco, Sociedad Española de Cardiología, Madrid, Spain; Servicio de Cardiología, Hospital Universitario Marqués de Valdecilla, Santander, Spain. Electronic address: cargvf@gmail.com. 2. Servicio de Cardiología, Clínica Puerta de Hierro, Majadahonda, Madrid, Spain. 3. Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain. 4. Servicio de Cardiología, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain. 5. Servicio de Cardiología, Hospital Universitario Reina Sofía, Córdoba, Spain. 6. Servicio de Cardiología (Adultos), Hospital Universitario Gregorio Marañón, Madrid, Spain. 7. Servicio de Cardiología, Hospital Universitario 12 de Octubre, Madrid, Spain. 8. Servicio de Cardiología, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain. 9. Servicio de Cardiología, Hospital Universitario Virgen del Rocío, Sevilla, Spain. 10. Servicio de Cardiología, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
Abstract
INTRODUCTION AND OBJECTIVES: The present article reports the characteristics and results of heart transplantation in Spain since this therapeutic modality was first used in May 1984. METHODS: We summarize the main features of recipients, donors, and surgical procedures, as well as the results of all heart transplantations performed in Spain until December 31, 2012. RESULTS: A total of 247 heart transplantations were performed in 2012. The whole series consisted of 6775 procedures. Recent years have seen a progressive worsening in the clinical characteristics of recipients (34% aged over 60 years, 22% with severe kidney failure, 17% with insulin-dependent diabetes, 29% with previous heart surgery, 16% under mechanical ventilation) and donors (38% aged over 45 years, 26% with recipient: donor weight mismatch>20%), and in surgical conditions (29% of procedures at >4 h ischemia and 36% as emergency transplantations). The probability of survival at 1, 5, 10, and 15 years of follow-up was 78%, 67%, 53%, and 38%, respectively. These results have remained stable since 1995. CONCLUSIONS: In recent years, the number of heart transplantations/year in Spain has remained stable at around 250. Despite the worsening of recipient and donor clinical characteristics and of time-to-surgery, the results in terms of mortality have remained stable and compare favorably with those of other countries.
INTRODUCTION AND OBJECTIVES: The present article reports the characteristics and results of heart transplantation in Spain since this therapeutic modality was first used in May 1984. METHODS: We summarize the main features of recipients, donors, and surgical procedures, as well as the results of all heart transplantations performed in Spain until December 31, 2012. RESULTS: A total of 247 heart transplantations were performed in 2012. The whole series consisted of 6775 procedures. Recent years have seen a progressive worsening in the clinical characteristics of recipients (34% aged over 60 years, 22% with severe kidney failure, 17% with insulin-dependent diabetes, 29% with previous heart surgery, 16% under mechanical ventilation) and donors (38% aged over 45 years, 26% with recipient: donor weight mismatch>20%), and in surgical conditions (29% of procedures at >4 h ischemia and 36% as emergency transplantations). The probability of survival at 1, 5, 10, and 15 years of follow-up was 78%, 67%, 53%, and 38%, respectively. These results have remained stable since 1995. CONCLUSIONS: In recent years, the number of heart transplantations/year in Spain has remained stable at around 250. Despite the worsening of recipient and donor clinical characteristics and of time-to-surgery, the results in terms of mortality have remained stable and compare favorably with those of other countries.
Authors: José-Luis López-Sendón; José Ramón González-Juanatey; Fausto Pinto; José Cuenca Castillo; Lina Badimón; Regina Dalmau; Esteban González Torrecilla; José Ramón López Mínguez; Alicia M Maceira; Domingo Pascual-Figal; José Luis Pomar Moya-Prats; Alessandro Sionis; José Luis Zamorano Journal: Eur Heart J Date: 2015-10-21 Impact factor: 29.983