| Literature DB >> 24772054 |
Valentina Berti, Lisa Mosconi, Alberto Pupi.
Abstract
Brain 18F-fluorodeoxyglucose (18F-FDG) PET allows the in vivo study of cerebral glucose metabolism, reflecting neuronal and synaptic activity. 18F-FDG-PET has been extensively used to detect metabolic alterations in several neurologic diseases compared with normal aging. However, healthy subjects have variants of 18F-FDG distribution, especially as associated with aging. This article focuses on 18F-FDG-PET findings in so-called normal brain aging, and in particular on metabolic differences occurring with aging and as a function of people’s gender. The effect of different substances, medications, and therapy procedures are discussed, as well as common artifacts.Entities:
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Year: 2014 PMID: 24772054 PMCID: PMC3998066 DOI: 10.1016/j.cpet.2013.10.006
Source DB: PubMed Journal: PET Clin ISSN: 1556-8598