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Literature DB >> 24768686

RNA epigenetics.

Abstract

Mammalian messenger RNA (mRNA) and long noncoding RNA (lncRNA) contain tens of thousands of posttranscriptional chemical modifications. Among these, the N(6)-methyl-adenosine (m(6)A) modification is the most abundant and can be removed by specific mammalian enzymes. m(6)A modification is recognized by families of RNA binding proteins that affect many aspects of mRNA function. mRNA/lncRNA modification represents another layer of epigenetic regulation of gene expression, analogous to DNA methylation and histone modification.

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Year: 2014 PMID： 24768686 PMCID： PMC4190089 DOI： 10.1016/j.trsl.2014.04.003

Source DB: PubMed Journal: Transl Res ISSN： 1878-1810 Impact factor: 7.012

79 in total

1. Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer.

Authors: Ainur Akilzhanova; Zhannur Nurkina; Kuvat Momynaliev; Erlan Ramanculov; Zhaxibai Zhumadilov; Zhaxybai Zhumadilov; Tolebay Rakhypbekov; Naomi Hayashida; Masahiro Nakashima; Noboru Takamura
Journal: Anticancer Res Date: 2013-09 Impact factor: 2.480

2. Variant rs1421085 in the FTO gene contribute childhood obesity in Chinese children aged 3-6 years.

Authors: Lina Wang; Qing Yu; Yan Xiong; Linfei Liu; Xuening Zhang; Zhen Zhang; Jianru Wu; Bei Wang
Journal: Obes Res Clin Pract Date: 2013 Jan-Feb Impact factor: 2.288

3. Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA.

Authors: Emily M Harcourt; Thomas Ehrenschwender; Pedro J Batista; Howard Y Chang; Eric T Kool
Journal: J Am Chem Soc Date: 2013-12-11 Impact factor: 15.419

4. Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a.

Authors: Fan Yang; Lin Miao; Yide Mei; Mian Wu
Journal: Cell Signal Date: 2013-03-23 Impact factor: 4.315

Review 5. N6-methyl-adenosine modification in messenger and long non-coding RNA.

Authors: Tao Pan
Journal: Trends Biochem Sci Date: 2013-01-19 Impact factor: 13.807

6. FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.

Authors: Ye Fu; Guifang Jia; Xueqin Pang; Richard N Wang; Xiao Wang; Charles J Li; Scott Smemo; Qing Dai; Kathleen A Bailey; Marcelo A Nobrega; Ke-Li Han; Qiang Cui; Chuan He
Journal: Nat Commun Date: 2013 Impact factor: 14.919

7. High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.

Authors: Schraga Schwartz; Sudeep D Agarwala; Maxwell R Mumbach; Marko Jovanovic; Philipp Mertins; Alexander Shishkin; Yuval Tabach; Tarjei S Mikkelsen; Rahul Satija; Gary Ruvkun; Steven A Carr; Eric S Lander; Gerald R Fink; Aviv Regev
Journal: Cell Date: 2013-11-21 Impact factor: 41.582

8. N6-methyladenosine-dependent regulation of messenger RNA stability.

Authors: Xiao Wang; Zhike Lu; Adrian Gomez; Gary C Hon; Yanan Yue; Dali Han; Ye Fu; Marc Parisien; Qing Dai; Guifang Jia; Bing Ren; Tao Pan; Chuan He
Journal: Nature Date: 2013-11-27 Impact factor: 49.962

9. Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA.

Authors: Nian Liu; Marc Parisien; Qing Dai; Guanqun Zheng; Chuan He; Tao Pan
Journal: RNA Date: 2013-10-18 Impact factor: 4.942

Review 10. N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function.

Authors: Yamei Niu; Xu Zhao; Yong-Sheng Wu; Ming-Ming Li; Xiu-Jie Wang; Yun-Gui Yang
Journal: Genomics Proteomics Bioinformatics Date: 2012-12-21 Impact factor: 7.691

43 in total

1. Global Epitranscriptomics Profiling of RNA Post-Transcriptional Modifications as an Effective Tool for Investigating the Epitranscriptomics of Stress Response.

Authors: Rebecca E Rose; Manuel A Pazos; M Joan Curcio; Daniele Fabris
Journal: Mol Cell Proteomics Date: 2016-01-05 Impact factor: 5.911

RNA epigenetics.

1. Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer.

2. Variant rs1421085 in the FTO gene contribute childhood obesity in Chinese children aged 3-6 years.

3. Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA.

4. Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a.

Review 5. N6-methyl-adenosine modification in messenger and long non-coding RNA.

6. FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.

7. High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.

8. N6-methyladenosine-dependent regulation of messenger RNA stability.

9. Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA.

Review 10. N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function.

1. Global Epitranscriptomics Profiling of RNA Post-Transcriptional Modifications as an Effective Tool for Investigating the Epitranscriptomics of Stress Response.

Review 2. Brain Theranostics and Radiotheranostics: Exosomes and Graphenes In Vivo as Novel Brain Theranostics.

Review 3. Detecting RNA modifications in the epitranscriptome: predict and validate.

4. Ultrastructural localization of 5-methylcytosine on DNA and RNA.

Review 5. Epigenetic role of N6-methyladenosine (m6A) RNA methylation in the cardiovascular system.

Review 6. Epigenetic mechanisms underlying nervous system diseases.

7. Identification and evaluation of hub mRNAs and long non-coding RNAs in neutrophils during sepsis.

Review 8. LncRNAs: key players and novel insights into cervical cancer.

9. Gas5 Exerts Tumor-suppressive Functions in Human Glioma Cells by Targeting miR-222.

Review 10. RNA therapy: Are we using the right molecules?