Literature DB >> 2476805

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

C Dingwall1, I Ernberg, M J Gait, S M Green, S Heaphy, J Karn, A D Lowe, M Singh, M A Skinner, R Valerio.   

Abstract

tat, the trans-activator protein for human immunodeficiency virus 1 (HIV-1), has been expressed in Escherichia coli from synthetic genes. Purified tat binds specifically to HIV-1 trans-activation-responsive region (TAR) RNA in gel-retardation, filter-binding, and immunoprecipitation assays. tat does not bind detectably to antisense TAR RNA sequences, cellular mRNA sequences, variant TAR RNA sequences with altered stem-loop structures, or TAR DNA.

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Year:  1989        PMID: 2476805      PMCID: PMC297963          DOI: 10.1073/pnas.86.18.6925

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  31 in total

1.  A high-efficiency HeLa cell nuclear transcription extract.

Authors:  D J Shapiro; P A Sharp; W W Wahli; M J Keller
Journal:  DNA       Date:  1988 Jan-Feb

2.  Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein.

Authors:  M Green; P M Loewenstein
Journal:  Cell       Date:  1988-12-23       Impact factor: 41.582

3.  Cloning and expression in E. coli of a synthetic gene for the bacteriocidal protein caltrin/seminalplasmin.

Authors:  S Heaphy; M Singh; M J Gait
Journal:  Protein Eng       Date:  1987 Oct-Nov

4.  Tat protein from human immunodeficiency virus forms a metal-linked dimer.

Authors:  A D Frankel; D S Bredt; C O Pabo
Journal:  Science       Date:  1988-04-01       Impact factor: 47.728

5.  Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism.

Authors:  I Edery; R Petryshyn; N Sonenberg
Journal:  Cell       Date:  1989-01-27       Impact factor: 41.582

6.  Cellular uptake of the tat protein from human immunodeficiency virus.

Authors:  A D Frankel; C O Pabo
Journal:  Cell       Date:  1988-12-23       Impact factor: 41.582

7.  Structural arrangements of transcription control domains within the 5'-untranslated leader regions of the HIV-1 and HIV-2 promoters.

Authors:  K A Jones; P A Luciw; N Duchange
Journal:  Genes Dev       Date:  1988-09       Impact factor: 11.361

8.  Developmental expression of a neurofilament-M and two vimentin-like genes in Xenopus laevis.

Authors:  C R Sharpe
Journal:  Development       Date:  1988-06       Impact factor: 6.868

9.  Mutational analysis of the 5' non-coding region of human immunodeficiency virus type 1: effects of secondary structure on translation.

Authors:  N T Parkin; E A Cohen; A Darveau; C Rosen; W Haseltine; N Sonenberg
Journal:  EMBO J       Date:  1988-09       Impact factor: 11.598

10.  Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation.

Authors:  J A Garcia; D Harrich; E Soultanakis; F Wu; R Mitsuyasu; R B Gaynor
Journal:  EMBO J       Date:  1989-03       Impact factor: 11.598

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  211 in total

1.  Nuclear localization and shuttling of herpes simplex virus tegument protein VP13/14.

Authors:  M Donnelly; G Elliott
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

2.  Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences.

Authors:  Cyril F Bourgeois; Young Kyeung Kim; Mark J Churcher; Michelle J West; Jonathan Karn
Journal:  Mol Cell Biol       Date:  2002-02       Impact factor: 4.272

3.  Exciton interaction in molecular beacons: a sensitive sensor for short range modifications of the nucleic acid structure.

Authors:  S Bernacchi; Y Mély
Journal:  Nucleic Acids Res       Date:  2001-07-01       Impact factor: 16.971

Review 4.  Acetylation of histones and transcription-related factors.

Authors:  D E Sterner; S L Berger
Journal:  Microbiol Mol Biol Rev       Date:  2000-06       Impact factor: 11.056

5.  Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors.

Authors:  Lindsey Reynolds; Christopher Ullman; Michael Moore; Mark Isalan; Michelle J West; Paul Clapham; Aaron Klug; Yen Choo
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-06       Impact factor: 11.205

6.  Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro.

Authors:  C A Bohan; F Kashanchi; B Ensoli; L Buonaguro; K A Boris-Lawrie; J N Brady
Journal:  Gene Expr       Date:  1992

Review 7.  Mechanism of action of regulatory proteins encoded by complex retroviruses.

Authors:  B R Cullen
Journal:  Microbiol Rev       Date:  1992-09

8.  Circular dichroism and molecular modeling yield a structure for the complex of human immunodeficiency virus type 1 trans-activation response RNA and the binding region of Tat, the trans-acting transcriptional activator.

Authors:  E P Loret; P Georgel; W C Johnson; P S Ho
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

9.  Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative.

Authors:  Sara Richter; Cristina Parolin; Barbara Gatto; Claudia Del Vecchio; Egidio Brocca-Cofano; Arnaldo Fravolini; Giorgio Palù; Manlio Palumbo
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

10.  Evidence for a base triple in the free HIV-1 TAR RNA.

Authors:  Hendrik Huthoff; Frederic Girard; Sybren S Wijmenga; Ben Berkhout
Journal:  RNA       Date:  2004-03       Impact factor: 4.942

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