Xenia Weiner1, Martin Baumeister1, Thomas Kohnen1, Jens Bühren2. 1. From the Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany. 2. From the Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany. Electronic address: buehren@em.uni-frankfurt.de.
Abstract
PURPOSE: To evaluate the repeatability of different lens densitometry analysis modes performed with Scheimpflug imaging using the Pentacam HR device. SETTING: University eye hospital, Frankfurt am Main, Germany. DESIGN: Cross-sectional study. METHODS: Eyes were analyzed under mydriasis during 2 examinations performed by the same examiner. Three single measurements were taken to assess lens densitometry via 3 modes as follows: peak (maximum), linear (vertical axis), and 3-dimensional (3-D). Measurements were also taken using 3 cylindrical reference blocks (P) with different diameters (2.0 mm, 4.0 mm, 6.00 mm) composing the whole lens depth. Repeatability was tested using Bland-Altman analysis. As statistical parameters, the coefficient of repeatability (CoR) and the relative repeatability (RR) were applied. RESULTS: The study analyzed 105 eyes. The CoR of the peak modus was 5.6 (RR, 29.8%); of the linear modus, 0.9 (RR, 8.8%); and of the 3-D modus, 0.36 (RR, 3.6%). The values of the P mode were lower, with a CoR between 0.19 and 0.30 (RR, 2.1%-3.3%). CONCLUSIONS: Lens densitometry using Scheimpflug imaging was highly repeatable. However, repeatability was dependent on the analysis mode used. Repeatability decreased with increasing opacification.
PURPOSE: To evaluate the repeatability of different lens densitometry analysis modes performed with Scheimpflug imaging using the Pentacam HR device. SETTING: University eye hospital, Frankfurt am Main, Germany. DESIGN: Cross-sectional study. METHODS: Eyes were analyzed under mydriasis during 2 examinations performed by the same examiner. Three single measurements were taken to assess lens densitometry via 3 modes as follows: peak (maximum), linear (vertical axis), and 3-dimensional (3-D). Measurements were also taken using 3 cylindrical reference blocks (P) with different diameters (2.0 mm, 4.0 mm, 6.00 mm) composing the whole lens depth. Repeatability was tested using Bland-Altman analysis. As statistical parameters, the coefficient of repeatability (CoR) and the relative repeatability (RR) were applied. RESULTS: The study analyzed 105 eyes. The CoR of the peak modus was 5.6 (RR, 29.8%); of the linear modus, 0.9 (RR, 8.8%); and of the 3-D modus, 0.36 (RR, 3.6%). The values of the P mode were lower, with a CoR between 0.19 and 0.30 (RR, 2.1%-3.3%). CONCLUSIONS: Lens densitometry using Scheimpflug imaging was highly repeatable. However, repeatability was dependent on the analysis mode used. Repeatability decreased with increasing opacification.
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