Literature DB >> 33118095

Assessment of cataract forming effect of diabetes in young adults by lens densitometer.

Neslihan Bayraktar Bilen1, Murat Sinan Sarıcaoğlu2.   

Abstract

PURPOSE: To investigate the effect of the diabetes on cataract formation by Pentacam Scheimpflug topography system.
MATERIALS AND METHODS: Thirty diabetic patients and thirty-five healthy control subjects were included in the study. Exclusion criteria were smoking, high refractive error, any systemic disease or drug usage associated with cataract formation and to have diabetic retinopathy. The duration of diabetes and HbA1c level were recorded. A comprehensive ophthalmologic examination was performed in all cases. Pentacam (Oculus, Wetzlar, Germany) three-dimensional lens densitometer module was used to measure density of anterior, nuclear and posterior lens regions.
RESULTS: Mean age of group 1 and group 2 was 37.80 ± 5.51 years and 36.51 ± 3.77 years, respectively. There were not any difference between groups in the means of age and sex (P = .271; P = .700). The mean duration of diabetes in group 1 was 4.23 ± 3.71 years (6 months-10 year). The mean HbA1c level was 8.12 ± 2.07% (5.4-12.7%). Anterior, nuclear and posterior mean lens densitometry measurements were significantly higher in group 1 (diabetic group) than group 2 (control group) [(8.90 ± 0.59%; 8.05 ± 0.72% P =  < .001), (7.52 ± 0.31%; 7.00 ± 0.59% P =  < .001), (7.25 ± 0.31%; 6.90 ± 0.73% P = .006), respectively].
CONCLUSION: Diabetes may have cataractous effect in anterior, nuclear and posterior regions of the lens.

Entities:  

Keywords:  Anterior cataract; Diabetes; Lens densitometer; Nuclear cataract; Pentacam scheimpflug camera; Posterior cataract

Mesh:

Year:  2020        PMID: 33118095     DOI: 10.1007/s10792-020-01523-0

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  25 in total

1.  The effect of chronic smoking on lens density in young adults.

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2.  Risk factors for cortical, nuclear, posterior subcapsular, and mixed lens opacities: the Los Angeles Latino Eye Study.

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4.  Incidence of cataract surgery in the Wisconsin Epidemiologic Study of Diabetic Retinopathy.

Authors:  B E Klein; R Klein; S E Moss
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5.  Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence.

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6.  Enhanced diabetes-induced cataract in copper-zinc superoxide dismutase-null mice.

Authors:  Eva M Olofsson; Stefan L Marklund; Anders Behndig
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-03-25       Impact factor: 4.799

7.  The Lens Opacities Case-Control Study. Risk factors for cataract.

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Journal:  Arch Ophthalmol       Date:  1991-02

Review 8.  Meta-analysis of the risk of cataract in type 2 diabetes.

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Journal:  BMC Ophthalmol       Date:  2014-07-24       Impact factor: 2.209

Review 9.  Cataract in diabetes mellitus.

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Journal:  World J Diabetes       Date:  2019-03-15

Review 10.  Ocular Complications of Diabetes and Therapeutic Approaches.

Authors:  Victoria J Vieira-Potter; Dimitrios Karamichos; Darren J Lee
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