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Literature DB >> 24761306

Speckle contrast optical tomography: A new method for deep tissue three-dimensional tomography of blood flow.

Hari M Varma¹, Claudia P Valdes¹, Anna K Kristoffersen², Joseph P Culver³, Turgut Durduran².

Abstract

A novel tomographic method based on the laser speckle contrast, speckle contrast optical tomography (SCOT) is introduced that allows us to reconstruct three dimensional distribution of blood flow in deep tissues. This method is analogous to the diffuse optical tomography (DOT) but for deep tissue blood flow. We develop a reconstruction algorithm based on first Born approximation to generate three dimensional distribution of flow using the experimental data obtained from tissue simulating phantoms.

Keywords: (110.3010) Image reconstruction techniques; (110.6150) Speckle imaging; (110.6955) Tomographic imaging; (170.3880) Medical and biological imaging

Year: 2014 PMID： 24761306 PMCID： PMC3986001 DOI： 10.1364/BOE.5.001275

Source DB: PubMed Journal: Biomed Opt Express ISSN： 2156-7085 Impact factor: 3.732

27 in total

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Authors: Tanja Dragojević; Danilo Bronzi; Hari M Varma; Claudia P Valdes; Clara Castellvi; Federica Villa; Alberto Tosi; Carles Justicia; Franco Zappa; Turgut Durduran
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6. Simultaneously extracting multiple parameters via multi-distance and multi-exposure diffuse speckle contrast analysis.

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7. Recovery of the diffuse correlation spectroscopy data-type from speckle contrast measurements: towards low-cost, deep-tissue blood flow measurements.

Authors: K Murali; A K Nandakumaran; Turgut Durduran; Hari M Varma
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