Literature DB >> 24760221

Polycyclic aromatic hydrocarbons, tobacco smoke, and epigenetic remodeling in asthma.

E C Klingbeil1, K M Hew, U C Nygaard, K C Nadeau.   

Abstract

Environmental determinants including aerosolized pollutants such as polycyclic aromatic hydrocarbons (PAHs) and tobacco smoke have been associated with exacerbation and increased incidence of asthma. The influence of aerosolized pollutants on the development of immune dysfunction in asthmatics has been suggested to be mediated through epigenetic remodeling. Genome accessibility and transcription are regulated primarily through DNA methylation, histone modification, and microRNA transcript silencing. Epigenetic remodeling has been shown in studies to be associated with Th2 polarization and associated cytokine and chemokine regulation in the development of asthma. This review will present evidence for the contribution of the aerosolized pollutants PAH and environmental tobacco smoke to epigenetic remodeling in asthma.

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Year:  2014        PMID： 24760221      PMCID： PMC4161467          DOI： 10.1007/s12026-014-8508-1

Source DB:  PubMed          Journal:  Immunol Res        ISSN： 0257-277X            Impact factor:   2.829


  36 in total

1.  Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke.

Authors:  Susan K Murphy; Abayomi Adigun; Zhiqing Huang; Francine Overcash; Frances Wang; Randy L Jirtle; Joellen M Schildkraut; Amy P Murtha; Edwin S Iversen; Cathrine Hoyo
Journal:  Gene       Date:  2011-12-20       Impact factor: 3.688

2.  AluYb8 insertion in the MUTYH gene and risk of early-onset breast and gastric cancers in the Chinese population.

Authors:  Ming Zhu; Xiaoxiang Chen; Huan Zhang; Nong Xiao; Changdong Zhu; Qiong He; Wenwen Guo; Zhenming Cai; Hongbing Shen; Yaping Wang
Journal:  Asian Pac J Cancer Prev       Date:  2011

3.  Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome.

Authors:  Emily S Wan; Weiliang Qiu; Andrea Baccarelli; Vincent J Carey; Helene Bacherman; Stephen I Rennard; Alvar Agusti; Wayne Anderson; David A Lomas; Dawn L Demeo
Journal:  Hum Mol Genet       Date:  2012-04-06       Impact factor: 6.150

4.  Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke.

Authors:  David Adenuga; Hongwei Yao; Thomas H March; Jeanclare Seagrave; Irfan Rahman
Journal:  Am J Respir Cell Mol Biol       Date:  2008-10-16       Impact factor: 6.914

Review 5.  Aryl hydrocarbon receptor and lung cancer.

Authors:  Junchieh J Tsay; Kam-Meng Tchou-Wong; Alissa K Greenberg; Harvey Pass; William N Rom
Journal:  Anticancer Res       Date:  2013-04       Impact factor: 2.480

6.  Placental DNA hypomethylation in association with particulate air pollution in early life.

Authors:  Bram G Janssen; Lode Godderis; Nicky Pieters; Katrien Poels; Michał Kiciński; Ann Cuypers; Frans Fierens; Joris Penders; Michelle Plusquin; Wilfried Gyselaers; Tim S Nawrot
Journal:  Part Fibre Toxicol       Date:  2013-06-07       Impact factor: 9.400

7.  Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children.

Authors:  Arunima Kohli; Marco A Garcia; Rachel L Miller; Christina Maher; Olivier Humblet; S Katharine Hammond; Kari Nadeau
Journal:  Clin Epigenetics       Date:  2012-09-25       Impact factor: 6.551

8.  450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy.

Authors:  Bonnie R Joubert; Siri E Håberg; Roy M Nilsen; Xuting Wang; Stein E Vollset; Susan K Murphy; Zhiqing Huang; Cathrine Hoyo; Øivind Midttun; Lea A Cupul-Uicab; Per M Ueland; Michael C Wu; Wenche Nystad; Douglas A Bell; Shyamal D Peddada; Stephanie J London
Journal:  Environ Health Perspect       Date:  2012-07-31       Impact factor: 9.031

9.  Maternal exposure to polycyclic aromatic hydrocarbons and 5'-CpG methylation of interferon-γ in cord white blood cells.

Authors:  Wan-yee Tang; Linda Levin; Glenn Talaska; Yuk Yin Cheung; Julie Herbstman; Deliang Tang; Rachel L Miller; Frederica Perera; Shuk-Mei Ho
Journal:  Environ Health Perspect       Date:  2012-05-04       Impact factor: 9.031

10.  Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells.

Authors:  Jing Liu; Luhua Zhang; Lisa C Winterroth; Marco Garcia; Shannon Weiman; Jillian W Wong; John B Sunwoo; Kari C Nadeau
Journal:  J Toxicol       Date:  2013-03-07
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  16 in total

Review 1.  Review of Environmental Impact on the Epigenetic Regulation of Atopic Diseases.

Authors:  Saman Sabounchi; Jenna Bollyky; Kari Nadeau
Journal:  Curr Allergy Asthma Rep       Date:  2015-06       Impact factor: 4.806

2.  Commentary: Tobacco smoking and asthma: multigenerational effects, epigenetics and multilevel causal mediation analysis.

Authors:  Onyebuchi A Arah
Journal:  Int J Epidemiol       Date:  2018-08-01       Impact factor: 7.196

3.  Exposure to polycyclic aromatic hydrocarbons, vitamin D, and lung function in children with asthma.

Authors:  Yueh-Ying Han; Franziska Rosser; Erick Forno; Juan C Celedón
Journal:  Pediatr Pulmonol       Date:  2018-06-26

4.  Aryl hydrocarbon receptor signaling promotes ORMDL3-dependent generation of sphingosine-1-phosphate by inhibiting sphingosine-1-phosphate lyase.

Authors:  Hsueh-Chun Wang; Tzu-Hsuan Wong; Li-Ting Wang; Hsiang-Han Su; Hsiu-Yueh Yu; Ai-Hsuan Wu; Yu-Chun Lin; Hua-Ling Chen; Jau-Ling Suen; Shih-Hsien Hsu; Li-Chen Chen; Yufeng Zhou; Shau-Ku Huang
Journal:  Cell Mol Immunol       Date:  2018-03-23       Impact factor: 11.530

5.  Detection of Serum microRNAs From Department of Defense Serum Repository: Correlation With Cotinine, Cytokine, and Polycyclic Aromatic Hydrocarbon Levels.

Authors:  Collynn F Woeller; Thomas H Thatcher; Daniel Van Twisk; Stephen J Pollock; Amanda Croasdell; Nina Kim; Philip K Hopke; Xiaoyan Xia; Juilee Thakar; Col Timothy M Mallon; Mark J Utell; Richard P Phipps
Journal:  J Occup Environ Med       Date:  2016-08       Impact factor: 2.162

6.  Understanding the Placental Biology of Tobacco Smoke, Nicotine, and Marijuana (THC) Exposures During Pregnancy.

Authors:  Sohini Banerjee; Alyssa Deacon; Melissa A Suter; Kjersti M Aagaard
Journal:  Clin Obstet Gynecol       Date:  2022-02-04       Impact factor: 1.966

Review 7.  Can exposure to environmental chemicals increase the risk of diabetes type 1 development?

Authors:  Johanna Bodin; Lars Christian Stene; Unni Cecilie Nygaard
Journal:  Biomed Res Int       Date:  2015-03-26       Impact factor: 3.411

8.  Smoking correlates with increased cytoskeletal protein-related coding region mutations in the lung and head and neck datasets of the cancer genome atlas.

Authors:  John M Yavorski; George Blanck
Journal:  Physiol Rep       Date:  2016-12

Review 9.  Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer.

Authors:  Rachel Stading; Grady Gastelum; Chun Chu; Weiwu Jiang; Bhagavatula Moorthy
Journal:  Semin Cancer Biol       Date:  2021-07-07       Impact factor: 15.707

Review 10.  The Effects of Nicotine on Development.

Authors:  Sharon A McGrath-Morrow; Julie Gorzkowski; Judith A Groner; Ana M Rule; Karen Wilson; Susanne E Tanski; Joseph M Collaco; Jonathan D Klein
Journal:  Pediatrics       Date:  2020-02-11       Impact factor: 9.703
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