AIM: We aimed to assess whether there is a significant relation between periodontal health status and inflammation in uremic patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and also to reveal the efficiency of periodontal treatment in patients with various degrees of periodontal problems. PATIENTS AND METHODS: Overall, 68 patients undergoing CAPD were included in the study. Clinical indices and measurements were obtained at baseline and panoramic radiographies were used for the diagnosis. According to the baseline values, patients were stratified into four groups according to the severity of periodontal problems as follows: healthy/gingivitis, slight-to-moderate, and severe periodontitis. A control examination was performed 3 months after the periodontal treatment for only 43 patients. Clinical and laboratory parameters before and after treatment were compared. RESULTS: The frequency of periodontal disease was found to be high in uremic patients on CAPD. The frequency and severity of periodontitis was also found to be significantly (p < 0.01) higher in patients with high sensitive C-reactive protein levels and longer duration of peritoneal dialysis (p < 0.01). In addition, the periodontitis rate was found to be higher in patients with cardiovascular disease (p < 0.05) and diabetes mellitus (p < 0.01). CONCLUSION: A meticulous periodontal examination should be a routine part of management of the uremic patients on CAPD because periodontal disease could be one of the hidden sources of unexplained inflammatory status.
AIM: We aimed to assess whether there is a significant relation between periodontal health status and inflammation in uremic patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and also to reveal the efficiency of periodontal treatment in patients with various degrees of periodontal problems. PATIENTS AND METHODS: Overall, 68 patients undergoing CAPD were included in the study. Clinical indices and measurements were obtained at baseline and panoramic radiographies were used for the diagnosis. According to the baseline values, patients were stratified into four groups according to the severity of periodontal problems as follows: healthy/gingivitis, slight-to-moderate, and severe periodontitis. A control examination was performed 3 months after the periodontal treatment for only 43 patients. Clinical and laboratory parameters before and after treatment were compared. RESULTS: The frequency of periodontal disease was found to be high in uremic patients on CAPD. The frequency and severity of periodontitis was also found to be significantly (p < 0.01) higher in patients with high sensitive C-reactive protein levels and longer duration of peritoneal dialysis (p < 0.01). In addition, the periodontitis rate was found to be higher in patients with cardiovascular disease (p < 0.05) and diabetes mellitus (p < 0.01). CONCLUSION: A meticulous periodontal examination should be a routine part of management of the uremic patients on CAPD because periodontal disease could be one of the hidden sources of unexplained inflammatory status.
Authors: Dan Zhao; Abrar Tahir Khawaja; Lijian Jin; Kam Wa Chan; Maurizio Tonetti; Sydney Chi Wai Tang; George Pelekos Journal: Clin Oral Investig Date: 2019-11-12 Impact factor: 3.573
Authors: Marinella Ruospo; Suetonia C Palmer; Germaine Wong; Jonathan C Craig; Massimo Petruzzi; Michele De Benedittis; Pauline Ford; David W Johnson; Marcello Tonelli; Patrizia Natale; Valeria Saglimbene; Fabio Pellegrini; Eduardo Celia; Ruben Gelfman; Miguel R Leal; Marietta Torok; Paul Stroumza; Anna Bednarek-Skublewska; Jan Dulawa; Luc Frantzen; Domingo Del Castillo; Staffan Schon; Amparo G Bernat; Jorgen Hegbrant; Charlotta Wollheim; Letizia Gargano; Casper P Bots; Giovanni Fm Strippoli Journal: BMC Nephrol Date: 2017-05-22 Impact factor: 2.388