PURPOSE: Intramyocardial hemorrhage and area at risk are both prognostic markers in acute myocardial infarction (AMI). Myocardial T2 and T2 * mapping have been used to detect such tissue changes at 1.5T but these techniques are challenging at 3.0T due to additional susceptibility variation. We studied T2 and T2 * myocardial mapping techniques at 3.0T on a system employing B1 shimming and compared two different methods of B0 shimming. MATERIALS AND METHODS: Fifteen volunteers and six AMI patients were scanned on a 3T system. Volume and image-based (IB) B0 shimming techniques were implemented. Single breath-hold, multiecho gradient, and spin echo sequences were employed from which T2 * and T2 maps were calculated. RESULTS: In volunteers, there was no significant difference in mean values obtained with volume or IB shimming for T2 mapping (39.1 ± 6.0 msec vs. 39.4 ± 6.1 msec; P > 0.05) or for T2 * mapping (24.2 ± 6.7 msec vs. 24.1 ± 5.2 msec; P > 0.05). There were no significant regional differences in mean T2 values between septal, anterior, and posterior segments with either shimming technique (all P > 0.05); but there were significant regional differences in mean T2 * values using volume shimming (27.8 ± 5.2 msec vs. 28.4 ± 5.8 msec vs. 15.9 ± 8.3 msec; P < 0.05)-but not with IB shimming (25.7 ± 5.4 msec vs. 25.3 ± 5.9 msec vs. 18.7 ± 4.6 msec; P > 0.05). CONCLUSION: At 3.0T, cardiac T2 mapping is robust. Although T2 * mapping is prone to more regional heterogeneity this can be reduced by using IB instead of conventional volume B0 shimming.
PURPOSE: Intramyocardial hemorrhage and area at risk are both prognostic markers in acute myocardial infarction (AMI). Myocardial T2 and T2 * mapping have been used to detect such tissue changes at 1.5T but these techniques are challenging at 3.0T due to additional susceptibility variation. We studied T2 and T2 * myocardial mapping techniques at 3.0T on a system employing B1 shimming and compared two different methods of B0 shimming. MATERIALS AND METHODS: Fifteen volunteers and six AMI patients were scanned on a 3T system. Volume and image-based (IB) B0 shimming techniques were implemented. Single breath-hold, multiecho gradient, and spin echo sequences were employed from which T2 * and T2 maps were calculated. RESULTS: In volunteers, there was no significant difference in mean values obtained with volume or IB shimming for T2 mapping (39.1 ± 6.0 msec vs. 39.4 ± 6.1 msec; P > 0.05) or for T2 * mapping (24.2 ± 6.7 msec vs. 24.1 ± 5.2 msec; P > 0.05). There were no significant regional differences in mean T2 values between septal, anterior, and posterior segments with either shimming technique (all P > 0.05); but there were significant regional differences in mean T2 * values using volume shimming (27.8 ± 5.2 msec vs. 28.4 ± 5.8 msec vs. 15.9 ± 8.3 msec; P < 0.05)-but not with IB shimming (25.7 ± 5.4 msec vs. 25.3 ± 5.9 msec vs. 18.7 ± 4.6 msec; P > 0.05). CONCLUSION: At 3.0T, cardiac T2 mapping is robust. Although T2 * mapping is prone to more regional heterogeneity this can be reduced by using IB instead of conventional volume B0 shimming.
Authors: Sebastian Weingärtner; Fabian Zimmer; Gregory J Metzger; Kâmil Uğurbil; Pierre-Francois Van de Moortele; Mehmet Akçakaya Journal: Magn Reson Med Date: 2016-09-07 Impact factor: 4.668
Authors: Ananth Kidambi; John D Biglands; David M Higgins; David P Ripley; Arshad Zaman; David A Broadbent; Adam K McDiarmid; Peter P Swoboda; Tarique Al Musa; Bara Erhayiem; John P Greenwood; Sven Plein Journal: J Cardiovasc Magn Reson Date: 2014-10-28 Impact factor: 5.364
Authors: Ingo Hermann; Peter Kellman; Omer B Demirel; Mehmet Akçakaya; Lothar R Schad; Sebastian Weingärtner Journal: Magn Reson Med Date: 2021-03-29 Impact factor: 4.668
Authors: Heerajnarain Bulluck; Stefania Rosmini; Amna Abdel-Gadir; Anish N Bhuva; Thomas A Treibel; Marianna Fontana; Esther Gonzalez-Lopez; Manish Ramlall; Ashraf Hamarneh; Alex Sirker; Anna S Herrey; Charlotte Manisty; Derek M Yellon; James C Moon; Derek J Hausenloy Journal: J Magn Reson Imaging Date: 2017-02-15 Impact factor: 4.813
Authors: Arka Das; Christopher Kelly; Irvin Teh; Noor Sharrack; Christian T Stoeck; Sebastian Kozerke; Jürgen E Schneider; Sven Plein; Erica Dall'Armellina Journal: J Magn Reson Imaging Date: 2022-01-12 Impact factor: 5.119
Authors: G J H Snel; M van den Boomen; L M Hernandez; C T Nguyen; D E Sosnovik; B K Velthuis; R H J A Slart; R J H Borra; N H J Prakken Journal: J Cardiovasc Magn Reson Date: 2020-05-11 Impact factor: 5.364
Authors: Marco Wiesmueller; Wolfgang Wuest; Rafael Heiss; Christoph Treutlein; Michael Uder; Matthias Stefan May Journal: J Cardiovasc Magn Reson Date: 2020-05-28 Impact factor: 5.364