Literature DB >> 24752473

Herbal medicine in the treatment of Alzheimer's disease.

Jian-guo Wu1, Yan-yan Wang, Zi-lv Zhang, Bin Yu.   

Abstract

Associated with the aging of our world population is a sharp increase in the incidence of Alzheimer's disease, which not only poses a significant health issue but also presents a serious social problem. Although pharmacological treatments were developed based on existing hypotheses, the disease pathogenesis remains to be fully elucidated. Given the complexity of Alzheimer's disease, Chinese herbal medicine appears to have therapeutic potential for Alzheimer's disease through multi-target and multi-pathway approach at cellular and molecular levels and holistic adjustment of the body at organ system levels. Recently, a significant breakthrough has been made in the research of Chinese medicine for Alzheimer's disease. In this article, we review the experimental research progress in understanding how Chinese medicine could be used for the treatment of Alzheimer's disease.

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Year:  2014        PMID: 24752473     DOI: 10.1007/s11655-014-1337-y

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  43 in total

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3.  Decreased accumulation of subcellular amyloid-β with improved mitochondrial function mediates the neuroprotective effect of huperzine A.

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Review 5.  Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine.

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Journal:  Acta Pharmacol Sin       Date:  2006-01       Impact factor: 6.150

6.  Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.

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Review 7.  From traditional European medicine to discovery of new drug candidates for the treatment of dementia and Alzheimer's disease: acetylcholinesterase inhibitors.

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8.  Effects of ginsenoside Rb1 on central cholinergic metabolism.

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Review 2.  Bioactive components of Chinese herbal medicine enhance endogenous neurogenesis in animal models of ischemic stroke: A systematic analysis.

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Review 3.  Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid Β-Induced Axonal Degeneration in Alzheimer's Disease.

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Review 4.  Alzheimer's disease treatment: The share of herbal medicines.

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Journal:  Iran J Basic Med Sci       Date:  2021-02       Impact factor: 2.699

5.  Erzhi pills ameliorate cognitive dysfunction and alter proteomic hippocampus profiles induced by d-galactose and Aβ1-40 injection in ovariectomized Alzheimer's disease model rats.

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  5 in total

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