Literature DB >> 24747845

Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity.

Rajeshwari Sivaraj1, Pattanathu K S M Rahman2, P Rajiv3, S Narendhran3, R Venckatesh4.   

Abstract

Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A.indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A.indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Acalypha indica; Antimicrobial; Biological method; Copper oxide nanoparticles; Cytotoxicity

Mesh：

Substances：

Year:  2014        PMID： 24747845     DOI： 10.1016/j.saa.2014.03.027

Source DB:  PubMed          Journal:  Spectrochim Acta A Mol Biomol Spectrosc        ISSN： 1386-1425            Impact factor:   4.098


  20 in total

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