Literature DB >> 24740318

Does operative time affect infection rate in primary total knee arthroplasty?

Sameer Naranje1, Lisa Lendway, Susan Mehle, Terence J Gioe.   

Abstract

BACKGROUND: Prolonged operative time may increase the risk of infection after total knee arthroplasty (TKA). Both surgeon-related and patient-related factors can contribute to increased operative times. QUESTIONS/PURPOSES: The purpose of this study was to determine (1) whether increased operative time is an independent risk factor for revision resulting from infection after TKA; (2) whether increasing body mass index (BMI) increased operative time; and (3) whether increasing experience substantially decreased operative time.
METHODS: We retrospectively evaluated primary TKAs from our joint registry between March 2000 and August 2012. Cox proportional hazard models were used to assess the relationship between operative time and revision resulting from infection after accounting for age, sex, BMI, and Agency for Healthcare Research and Quality comorbidity score. Of 9973 instances of primary TKA, 73 underwent revision surgery for infection (0.73%).
RESULTS: After accounting for the confounders of age and sex, operative time was not found to have a significant effect; a 15-minute increase in operative time increased the hazard of revision resulting from infection by only 15.6% (p=0.053; 95% confidence interval, 0.0%-34.0%). In addition, a five-unit increase in BMI was found to increase mean operative time by 1.9 minutes, on average, regardless of sex (p<0.0001). Operative time decreases with increasing experience but appears to plateau at approximately 300 surgeries.
CONCLUSIONS: Operative time is only one of many factors that may increase infection risk and may be influenced by numerous confounders. Increasing BMI increased operative time but the effect was modest. The effect of increasing experience on operative duration of this common procedure was surprisingly limited among our surgeons. LEVEL OF EVIDENCE: Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

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Year:  2015        PMID: 24740318      PMCID: PMC4390911          DOI: 10.1007/s11999-014-3628-4

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  34 in total

1.  Suitability of the NNIS index for estimating surgical-site infection risk at a small university hospital in Brazil.

Authors:  M L Campos; Z M Cipriano; P F Freitas
Journal:  Infect Control Hosp Epidemiol       Date:  2001-05       Impact factor: 3.254

2.  Minimally invasive total knee arthroplasty compared with traditional total knee arthroplasty. Assessment of the learning curve and the postoperative recuperative period.

Authors:  Jason King; Daniel L Stamper; Douglas C Schaad; Seth S Leopold
Journal:  J Bone Joint Surg Am       Date:  2007-07       Impact factor: 5.284

3.  Higher body mass index leads to longer operative time in total knee arthroplasty.

Authors:  Barthelemy Liabaud; David A Patrick; Jeffrey A Geller
Journal:  J Arthroplasty       Date:  2012-11-08       Impact factor: 4.757

4.  Reason for revision TKA predicts clinical outcome: prospective evaluation of 150 consecutive patients with 2-years followup.

Authors:  Robin W T M van Kempen; Janneke J P Schimmel; Gijs G van Hellemondt; Hilde Vandenneucker; Ate B Wymenga
Journal:  Clin Orthop Relat Res       Date:  2013-03-30       Impact factor: 4.176

5.  Risk factors for total knee arthroplasty aseptic revision.

Authors:  Robert S Namba; Guy Cafri; Monti Khatod; Maria C S Inacio; Timothy W Brox; Elizabeth W Paxton
Journal:  J Arthroplasty       Date:  2013-08-15       Impact factor: 4.757

6.  Prosthetic joint infection risk after TKA in the Medicare population.

Authors:  Steven M Kurtz; Kevin L Ong; Edward Lau; Kevin J Bozic; Daniel Berry; Javad Parvizi
Journal:  Clin Orthop Relat Res       Date:  2009-08-08       Impact factor: 4.176

7.  Relationship between knee anthropometry and surgical time in total knee arthroplasty in severely and morbidly obese patients: a new prognostic index of surgical difficulty.

Authors:  L M Lozano; M Núñez; J M Segur; F Maculé; S Sastre; E Núñez; S Suso
Journal:  Obes Surg       Date:  2008-05-28       Impact factor: 4.129

8.  Risk factors associated with deep surgical site infections after primary total knee arthroplasty: an analysis of 56,216 knees.

Authors:  Robert S Namba; Maria C S Inacio; Elizabeth W Paxton
Journal:  J Bone Joint Surg Am       Date:  2013-05-01       Impact factor: 5.284

9.  Prolonged operative time correlates with increased infection rate after total knee arthroplasty.

Authors:  G Peersman; R Laskin; J Davis; M G E Peterson; T Richart
Journal:  HSS J       Date:  2006-02

Review 10.  The role of surgeon volume on patient outcome in total knee arthroplasty: a systematic review of the literature.

Authors:  Rick L Lau; Anthony V Perruccio; Rajiv Gandhi; Nizar N Mahomed
Journal:  BMC Musculoskelet Disord       Date:  2012-12-14       Impact factor: 2.362

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  24 in total

1.  Evaluation of running knotless barbed suture for capsular closure in primary total knee arthroplasty for osteoarthritis-a prospective randomized study.

Authors:  Rajesh Malhotra; Vaibhav Jain; Vijay Kumar; Deepak Gautam
Journal:  Int Orthop       Date:  2017-06-21       Impact factor: 3.075

2.  What are the important manoeuvres for beginners to minimize surgical time in primary total knee arthroplasty?

Authors:  Kengo Harato; Shinichi Maeno; Hidenori Tanikawa; Kazuya Kaneda; Yutaro Morishige; So Nomoto; Yasuo Niki
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-03-06       Impact factor: 4.342

3.  Variation on a technique for the intra-muscular insertion of nerve endings to minimise neuropathic and residual pain in lower limb amputees: a retrospective cohort study.

Authors:  Victor Lu; Andrew Zhou; Matija Krkovic
Journal:  Eur J Orthop Surg Traumatol       Date:  2022-05-25

4.  Intraoperative technology increases operating room times in primary total knee arthroplasty.

Authors:  Stephen G Zak; David Cieremans; Alex Tang; Ran Schwarzkopf; Joshua C Rozell
Journal:  Arch Orthop Trauma Surg       Date:  2022-05-12       Impact factor: 3.067

5.  Is sequential bilateral robotic total knee arthroplasty a safe procedure? A matched comparative pilot study.

Authors:  Cécile Batailler; Mike B Anderson; Xavier Flecher; Matthieu Ollivier; Sébastien Parratte
Journal:  Arch Orthop Trauma Surg       Date:  2022-05-10       Impact factor: 3.067

6.  Operative Time and Risk of Surgical Site Infection and Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis.

Authors:  Noah M Scigliano; Christopher N Carender; Natalie A Glass; Jennifer Deberg; Nicholas A Bedard
Journal:  Iowa Orthop J       Date:  2022-06

7.  The effect of operative time on in-hospital length of stay in revision total knee arthroplasty.

Authors:  Luke J Garbarino; Peter A Gold; Nipun Sodhi; Hiba K Anis; Joseph O Ehiorobo; Sreevathsa Boraiah; Jonathan R Danoff; Vijay J Rasquinha; Carlos A Higuera-Rueda; Michael A Mont
Journal:  Ann Transl Med       Date:  2019-02

8.  Predictive factors for longer operative times in patients with medial knee osteoarthritis undergoing total knee arthroplasty.

Authors:  Yoshinori Ishii; Hideo Noguchi; Junko Sato; Hana Ishii; Ryo Ishii; Shin-Ichi Toyabe
Journal:  J Orthop       Date:  2020-01-25

9.  Tranexamic Acid in a Multimodal Blood Loss Prevention Protocol to Decrease Blood Loss in Revision Total Knee Arthroplasty: A Cohort Study.

Authors:  Miguel Ortega-Andreu; Gloria Talavera; Norma G Padilla-Eguiluz; Hanna Perez-Chrzanowska; Reyes Figueredo-Galve; Carlos E Rodriguez-Merchán; Enrique Gómez-Barrena
Journal:  Open Orthop J       Date:  2016-09-23

10.  Explanatory Factors for Periprosthetic Infection in Total Knee Arthroplasty.

Authors:  Alberto Delgado-González; Juan José Morales-Viaji; Guillermo Criado-Albillos; Adoración Del Pilar Martín-Rodríguez; Josefa González-Santos; Remedios López-Liria; Carla Collazo-Riobo; Raúl Soto-Cámara; Jerónimo J González-Bernal
Journal:  J Clin Med       Date:  2021-05-26       Impact factor: 4.241

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