| Literature DB >> 24740077 |
Yanjie Huang1, Karen C Carroll2, Sara E Cosgrove3, Pranita D Tamma4.
Abstract
As routine testing of clinical isolates for extended-spectrum β-lactamase (ESBL) production (screen plus phenotypic confirmatory testing) is no longer required by the Clinical and Laboratory Standards Institute (CLSI), a number of clinical microbiology laboratories use ceftriaxone MICs as a proxy means of identifying bacteria as potential ESBL producers. Data from 1,386 clinical isolates suggest that a ceftriaxone MIC cutoff of 8 μg/ml is an excellent predictor of ESBL production, with a positive predictive value and negative predictive value approaching 100% and 99.5%, respectively.Entities:
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Year: 2014 PMID: 24740077 PMCID: PMC4042788 DOI: 10.1128/JCM.00716-14
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948