Literature DB >> 24738011

Diffraction-limited ultrasensitive molecular nano-arrays with singular nano-cone scattering.

Yunshan Wang1, Ting-Chou Chang1, Paul R Stoddart2, Hsueh-Chia Chang1.   

Abstract

Large-library fluorescent molecular arrays remain limited in sensitivity (1 × 10(6) molecules) and dynamic range due to background auto-fluorescence and scattering noise within a large (20-100 μm) fluorescent spot. We report an easily fabricated silica nano-cone array platform, with a detection limit of 100 molecules and a dynamic range that spans 6 decades, due to point (10 nm to 1 μm) illumination of preferentially absorbed tagged targets by singular scattering off wedged cones. Its fluorescent spot reaches diffraction-limited submicron dimensions, which are 10(4) times smaller in area than conventional microarrays, with comparable reduction in detection limit and amplification of dynamic range.

Entities:  

Year:  2014        PMID： 24738011      PMCID： PMC3971819          DOI： 10.1063/1.4869694

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN： 1932-1058            Impact factor:   2.800


  17 in total

1.  A rapid field-use assay for mismatch number and location of hybridized DNAs.

Authors:  I-Fang Cheng; Satyajyoti Senapati; Xinguang Cheng; Sagnik Basuray; Hsien-Chang Chang; Hsueh-Chia Chang
Journal:  Lab Chip       Date:  2010-02-23       Impact factor: 6.799

2.  Opto-electrochemical nanosensor array for remote DNA detection.

Authors:  Frédérique Deiss; Sébastien Laurent; Emeline Descamps; Thierry Livache; Neso Sojic
Journal:  Analyst       Date:  2010-10-14       Impact factor: 4.616

3.  Development of a microfluidic platform with an optical imaging microarray capable of attomolar target DNA detection.

Authors:  Michaela Bowden; Linan Song; David R Walt
Journal:  Anal Chem       Date:  2005-09-01       Impact factor: 6.986

4.  An optimized isolation and labeling platform for accurate microRNA expression profiling.

Authors:  Jaclyn Shingara; Kerri Keiger; Jeffrey Shelton; Walairat Laosinchai-Wolf; Patricia Powers; Richard Conrad; David Brown; Emmanuel Labourier
Journal:  RNA       Date:  2005-07-25       Impact factor: 4.942

5.  Fluorescence near metal tips: The roles of energy transfer and surface plasmon polaritons.

Authors:  Nader A Issa; Reinhard Guckenberger
Journal:  Opt Express       Date:  2007-09-17       Impact factor: 3.894

Review 6.  Nanostructured optical fibre arrays for high-density biochemical sensing and remote imaging.

Authors:  F Deiss; N Sojic; D J White; P R Stoddart
Journal:  Anal Bioanal Chem       Date:  2009-11-15       Impact factor: 4.142

7.  A chemical-detecting system based on a cross-reactive optical sensor array.

Authors:  T A Dickinson; J White; J S Kauer; D R Walt
Journal:  Nature       Date:  1996-08-22       Impact factor: 49.962

8.  Nanoscale high-intensity light focusing with pure dielectric nonspherical scatterer.

Authors:  Vijay M Sundaram; Sy-bor Wen
Journal:  Opt Lett       Date:  2014-02-01       Impact factor: 3.776

9.  Enhanced Raman scattering from individual semiconductor nanocones and nanowires.

Authors:  Linyou Cao; Bahram Nabet; Jonathan E Spanier
Journal:  Phys Rev Lett       Date:  2006-04-18       Impact factor: 9.161

10.  Shear and AC Field Enhanced Carbon Nanotube Impedance Assay for Rapid, Sensitive, and Mismatch-Discriminating DNA Hybridization.

Authors:  Sagnik Basuray; Satyajyoti Senapati; Andrew Aijian; Andrew R Mahon; Hsueh-Chia Chang
Journal:  ACS Nano       Date:  2009-07-07       Impact factor: 15.881
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  7 in total

1.  Gold coated optical fibers as three-dimensional electrodes for microfluidic enzymatic biofuel cells: Toward geometrically enhanced performance.

Authors:  Denis Desmaële; Louis Renaud; Sophie Tingry
Journal:  Biomicrofluidics       Date:  2015-08-18       Impact factor: 2.800

Review 2.  Alternating current electrohydrodynamics in microsystems: Pushing biomolecules and cells around on surfaces.

Authors:  Ramanathan Vaidyanathan; Shuvashis Dey; Laura G Carrascosa; Muhammad J A Shiddiky; Matt Trau
Journal:  Biomicrofluidics       Date:  2015-12-08       Impact factor: 2.800

3.  A bead-based fluorescence immunosensing technique enabled by the integration of Förster resonance energy transfer and optoelectrokinetic concentration.

Authors:  Jhih-Cheng Wang; Hu-Yao Ku; Dar-Bin Shieh; Han-Sheng Chuang
Journal:  Biomicrofluidics       Date:  2016-01-28       Impact factor: 2.800

4.  Numerical simulation on the opto-electro-kinetic patterning for rapid concentration of particles in a microchannel.

Authors:  Dong Kim; Jaesool Shim; Han-Sheng Chuang; Kyung Chun Kim
Journal:  Biomicrofluidics       Date:  2015-05-13       Impact factor: 2.800

Review 5.  Future microfluidic and nanofluidic modular platforms for nucleic acid liquid biopsy in precision medicine.

Authors:  Ana Egatz-Gomez; Ceming Wang; Flora Klacsmann; Zehao Pan; Steve Marczak; Yunshan Wang; Gongchen Sun; Satyajyoti Senapati; Hsueh-Chia Chang
Journal:  Biomicrofluidics       Date:  2016-05-05       Impact factor: 2.800

6.  Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay.

Authors:  Arnold Chen; Royal Wang; Candace R S Bever; Siyuan Xing; Bruce D Hammock; Tingrui Pan
Journal:  Biomicrofluidics       Date:  2014-11-05       Impact factor: 2.800

Review 7.  Current Technologies and Recent Developments for Screening of HPV-Associated Cervical and Oropharyngeal Cancers.

Authors:  Sunny S Shah; Satyajyoti Senapati; Flora Klacsmann; Daniel L Miller; Jeff J Johnson; Hsueh-Chia Chang; M Sharon Stack
Journal:  Cancers (Basel)       Date:  2016-09-09       Impact factor: 6.639
  7 in total

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