Literature DB >> 24737162

Secondary hemophagocytic lymphohistiocytosis (HLH) from a presumed brown recluse spider bite.

Christopher Dandoy1, Michael Grimley.   

Abstract

Systemic loxoscelism is a rare complication after Loxosceles reclusa (brown recluse spider) envenomation. Loxosceles venom contains pro-inflammatory proteins, which have been shown to be elevated in patients with hemophagocytic lymph histiocytosis. We present a case of a 10-year-old male that developed presumed systemic loxoscelism, secondary hemophagocytic lymphohistiocytosis with hepatic dysfunction and renal failure. He was treated with dexamethasone and made a full recovery.

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Year:  2014        PMID： 24737162     DOI： 10.1007/s10875-014-0036-1

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  17 in total

1.  HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.

Authors:  Jan-Inge Henter; Annacarin Horne; Maurizio Aricó; R Maarten Egeler; Alexandra H Filipovich; Shinsaku Imashuku; Stephan Ladisch; Ken McClain; David Webb; Jacek Winiarski; Gritta Janka
Journal:  Pediatr Blood Cancer       Date:  2007-02       Impact factor: 3.167

Review 2.  Biotechnological applications of brown spider (Loxosceles genus) venom toxins.

Authors:  Andrea Senff-Ribeiro; Paulo Henrique da Silva; Olga Meiri Chaim; Luiza Helena Gremski; Kátia Sabrina Paludo; Rafael Bertoni da Silveira; Waldemiro Gremski; Oldemir Carlos Mangili; Silvio Sanches Veiga
Journal:  Biotechnol Adv       Date:  2007-12-23       Impact factor: 14.227

Review 3.  Loxoscelism: From basic research to the proposal of new therapies.

Authors:  Denise V Tambourgi; Rute M Gonçalves-de-Andrade; Carmen W van den Berg
Journal:  Toxicon       Date:  2010-02-06       Impact factor: 3.033

4.  Autopsy findings in 27 children with haemophagocytic lymphohistiocytosis.

Authors:  A Ost; S Nilsson-Ardnor; J I Henter
Journal:  Histopathology       Date:  1998-04       Impact factor: 5.087

Review 5.  Spider bite.

Authors:  Geoffrey K Isbister; Hui Wen Fan
Journal:  Lancet       Date:  2011-07-15       Impact factor: 79.321

6.  2011 Annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 29th Annual Report.

Authors:  Alvin C Bronstein; Daniel A Spyker; Louis R Cantilena; Barry H Rumack; Richard C Dart
Journal:  Clin Toxicol (Phila)       Date:  2012-12       Impact factor: 4.467

Review 7.  Advances in the management of hemophagocytic lymphohistiocytosis.

Authors:  S Imashuku
Journal:  Int J Hematol       Date:  2000-07       Impact factor: 2.490

8.  Loxosceles deserta spider venom induces NF-kappaB-dependent chemokine production by endothelial cells.

Authors:  A Desai; M J Miller; H F Gomez; J S Warren
Journal:  J Toxicol Clin Toxicol       Date:  1999

9.  Endotoxemic-like shock induced by Loxosceles spider venoms: pathological changes and putative cytokine mediators.

Authors:  D V Tambourgi; V L Petricevich; F C Magnoli; S L Assaf; S Jancar; W Dias Da Silva
Journal:  Toxicon       Date:  1998-02       Impact factor: 3.033

10.  Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome.

Authors:  Yongmin Tang; Xiaojun Xu; Hua Song; Shilong Yang; Shuwen Shi; Jian Wei; Binhua Pan; Fenying Zhao; Chan Liao; Chunfang Luo
Journal:  Br J Haematol       Date:  2008-07-31       Impact factor: 6.998
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  3 in total

1.  Evaluating the optimal serum ferritin level to identify hemophagocytic lymphohistiocytosis in the critical care setting.

Authors:  Hayder Saeed; Ryan R Woods; Joshua Lester; Roger Herzig; Zartash Gul; Gregory Monohan
Journal:  Int J Hematol       Date:  2015-05-22       Impact factor: 2.490

2.  Brown Recluse Spider Bites in Patients With Neutropenia: A Single-institution Experience.

Authors:  Diego R Hijano; Daniel Otterson; Maysam R Homsi; Yin Su; Li Tang; Jeannette Kirby; Miguela A Caniza
Journal:  J Pediatr Hematol Oncol       Date:  2019-01       Impact factor: 1.289

Review 3.  Highlights in the knowledge of brown spider toxins.

Authors:  Daniele Chaves-Moreira; Andrea Senff-Ribeiro; Ana Carolina Martins Wille; Luiza Helena Gremski; Olga Meiri Chaim; Silvio Sanches Veiga
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2017-02-08
  3 in total

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