| Literature DB >> 24735402 |
Jun-Feng Wang1, Fu-Quan Xu, Zhen Wang, Xin Lu, Jun-Ting Wan, Bin Yang, Xue-Feng Zhou, Tian-Yu Zhang, Zheng-Chao Tu, Yonghong Liu.
Abstract
One new naphthalene derivative, 1,8-dihydroxynaphthol-1-O-α-l-rhamnopyranoside (1), together with one known α-dibenzopyrone, alternariol (2), and five xanthones (3-7) were isolated from the sponge-derived fungus Arthrinium sp. ZSDS1-F3. All the isolated compounds (1-7) were established by comprehensive analysis of the spectral data, especially 1D and 2D NMR (HMQC and HMBC) spectra. In the primary bioassays, compound 3 exhibited moderate COX-2 inhibition, with IC50 values of 12.2 μM.Entities:
Keywords: Arthrinium sp.; naphthalene glycoside; secondary metabolite; sponge
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Year: 2014 PMID： 24735402 DOI： 10.1080/14786419.2014.905935
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861