Mohamed Awad Mousnad1, Asrul Akmal Shafie2, Mohamed Izham Ibrahim3. 1. Senior Specialist of Pharmacoeconomics & Pharmacoepidemiology, National Health Insurance Fund, Khartoum, Sudan. Electronic address: m_abdalaziz@yahoo.com. 2. Assoc. Professor, Programme Chair, Discipline of Social & Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia. 3. Professor of Social & Administrative Pharmacy, College of Pharmacy, Qatar University, Doha, Qatar.
Abstract
OBJECTIVE: To systematically identify the main factors contributing to the increase in pharmaceutical expenditures. METHODS: A systematic search of published studies was conducted utilising major widely used electronic databases using the search terms 'factors,' 'financing,' 'pharmaceutical,' and 'expenditures.' To be included, the studies needed to: (1) measure at least one of the following outcomes: total growth in pharmaceutical expenditures, price growth or quantity growth; (2) mention a clear method for analysing the impact of factors affecting the increases in drug expenditures; (3) be written in English. Nonprimary articles that were published only as an abstract, a review, a commentary or a letter were excluded. MAIN RESULTS: From a total of 2039 studies, only 25 were included in the full review. The main determinant categories that were identified in the review were factors related to price, utilisation, therapeutic choice, demand and health care system. CONCLUSIONS: The major cost drivers were found to be changes in drug quantities and therapies as well as new drugs. It is important for policymakers to understand pharmaceutical spending trends and the factors that influence them in order to formulate effective cost containment strategies and design optimum drug policy.
OBJECTIVE: To systematically identify the main factors contributing to the increase in pharmaceutical expenditures. METHODS: A systematic search of published studies was conducted utilising major widely used electronic databases using the search terms 'factors,' 'financing,' 'pharmaceutical,' and 'expenditures.' To be included, the studies needed to: (1) measure at least one of the following outcomes: total growth in pharmaceutical expenditures, price growth or quantity growth; (2) mention a clear method for analysing the impact of factors affecting the increases in drug expenditures; (3) be written in English. Nonprimary articles that were published only as an abstract, a review, a commentary or a letter were excluded. MAIN RESULTS: From a total of 2039 studies, only 25 were included in the full review. The main determinant categories that were identified in the review were factors related to price, utilisation, therapeutic choice, demand and health care system. CONCLUSIONS: The major cost drivers were found to be changes in drug quantities and therapies as well as new drugs. It is important for policymakers to understand pharmaceutical spending trends and the factors that influence them in order to formulate effective cost containment strategies and design optimum drug policy.
Authors: Wenjie Zeng; Alexander E Finlayson; Sushma Shankar; Winnie de Bruyn; Brian Godman Journal: BMC Health Serv Res Date: 2015-01-22 Impact factor: 2.655
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