Antonio Lasalvia1, Chiara Bonetto1, Sarah Tosato1, Gioia Zanatta1, Doriana Cristofalo1, Damiano Salazzari1, Lorenza Lazzarotto1, Mariaelena Bertani1, Sarah Bissoli1, Katia De Santi1, Carla Cremonese1, Moreno De Rossi1, Francesco Gardellin1, Luana Ramon1, Maria Zucchetto1, Francesco Amaddeo1, Michele Tansella1, Mirella Ruggeri1. 1. Antonio Lasalvia, MD, PhD, Chiara Bonetto, PhD, Sarah Tosato, MD, PhD, Gioia Zanatta, DClinPsy, Doriana Cristofalo, Edu Sci, Damiano Salazzari, Lorenza Lazzarotto, DClinPsy, Mariaelena Bertani, PhD, Sarah Bissoli, PhD, Katia De Santi, MD, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Verona; Carla Cremonese, MD, Psychiatric Clinic, Department of Neuroscience, University of Padua, Padua; Moreno De Rossi, MD, Department of Mental Health, NHS, Local Health Authority Adria, Rovigo; Francesco Gardellin, MD, Department of Mental Health, NHS, Local Health Authority Vicenza; Luana Ramon, MD, Department of Mental Health, NHS, Local Health Authority Portogruaro, Venezia; Maria Zucchetto, MD, Department of Mental Health, NHS, Local Health Authority Padua; Francesco Amaddeo, MD, PhD, Michele Tansella, MD, Mirella Ruggeri, MD, PhD, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Verona, Italy.
Abstract
BACKGROUND: Considerable variations in the incidence of psychosis have been observed across countries, in terms of age, gender, immigration status, urbanicity and socioeconomic deprivation. AIMS: To evaluate the incidence rate of first-episode psychosis in a large area of north-eastern Italy and the distribution of the above-mentioned risk factors in individuals with psychoses. METHOD: Epidemiologically based survey. Over a 3-year period individuals with psychosis on first contact with services were identified and diagnosed according to ICD-10 criteria. RESULTS: In total, 558 individuals with first-episode psychosis were identified during 3,077,555 person-years at risk. The annual incidence rate per 100,000 was 18.1 for all psychoses, 14.3 for non-affective psychoses and 3.8 for affective psychoses. The rate for all psychoses was higher in young people aged 20-29 (incidence rate ratio (IRR) = 4.18, 95% CI 2.77-6.30), immigrants (IRR = 2.26, 95% CI 1.85-2.75) and those living in the most deprived areas (IRR = 2.09, 95% CI 1.54-2.85). CONCLUSIONS: The incidence rate in our study area was lower than that found in other European and North American studies and provides new insights into the factors that may increase and/or decrease risk for developing psychosis. Royal College of Psychiatrists.
BACKGROUND: Considerable variations in the incidence of psychosis have been observed across countries, in terms of age, gender, immigration status, urbanicity and socioeconomic deprivation. AIMS: To evaluate the incidence rate of first-episode psychosis in a large area of north-eastern Italy and the distribution of the above-mentioned risk factors in individuals with psychoses. METHOD: Epidemiologically based survey. Over a 3-year period individuals with psychosis on first contact with services were identified and diagnosed according to ICD-10 criteria. RESULTS: In total, 558 individuals with first-episode psychosis were identified during 3,077,555 person-years at risk. The annual incidence rate per 100,000 was 18.1 for all psychoses, 14.3 for non-affective psychoses and 3.8 for affective psychoses. The rate for all psychoses was higher in young people aged 20-29 (incidence rate ratio (IRR) = 4.18, 95% CI 2.77-6.30), immigrants (IRR = 2.26, 95% CI 1.85-2.75) and those living in the most deprived areas (IRR = 2.09, 95% CI 1.54-2.85). CONCLUSIONS: The incidence rate in our study area was lower than that found in other European and North American studies and provides new insights into the factors that may increase and/or decrease risk for developing psychosis. Royal College of Psychiatrists.
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