Literature DB >> 24722947

CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4.

Takashi Nagasawa1.   

Abstract

Chemokines were recognized originally for their ability to dictate the migration and activation of leukocytes. However, CXC chemokine ligand 12 (CXCL12, also known as stromal cell-derived factor-1) and its receptor CXCR4 are the first chemokine and receptor that have been shown to be critical for developmental processes, including homing and maintenance of hematopoietic stem cells (HSCs), production of immune cells, homing of primordial germ cells (PGCs), cardiogenesis, arterial vessel branching in some organs, and appropriate assemblies of particular types of neurons. This review focuses on the pathophysiological relevance of CXCL12-CXCR4 signaling in mammals.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24722947     DOI： 10.1007/s00109-014-1123-8

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  65 in total

1.  The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes.

Authors:  Karl Balabanian; Bernard Lagane; Simona Infantino; Ken Y C Chow; Julie Harriague; Barbara Moepps; Fernando Arenzana-Seisdedos; Marcus Thelen; Françoise Bachelerie
Journal:  J Biol Chem       Date:  2005-08-17       Impact factor: 5.157

2.  Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.

Authors:  Q Ma; D Jones; P R Borghesani; R A Segal; T Nagasawa; T Kishimoto; R T Bronson; T A Springer
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-04       Impact factor: 11.205

3.  Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4.

Authors:  A Peled; I Petit; O Kollet; M Magid; T Ponomaryov; T Byk; A Nagler; H Ben-Hur; A Many; L Shultz; O Lider; R Alon; D Zipori; T Lapidot
Journal:  Science       Date:  1999-02-05       Impact factor: 47.728

4.  Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor.

Authors:  Meiling Lu; Elizabeth A Grove; Richard J Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-30       Impact factor: 11.205

5.  Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression.

Authors:  Yi-Shiuan Tzeng; Hung Li; Yuan-Lin Kang; Wen-Cheng Chen; Wei-Cheng Cheng; Dar-Ming Lai
Journal:  Blood       Date:  2010-09-10       Impact factor: 22.113

6.  The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells.

Authors:  Veysel Odemis; Jana Lipfert; Robert Kraft; Peter Hajek; Getu Abraham; Kirsten Hattermann; Rolf Mentlein; Jürgen Engele
Journal:  Glia       Date:  2011-11-14       Impact factor: 7.452

7.  Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.

Authors:  Frederic Sierro; Christine Biben; Laura Martínez-Muñoz; Mario Mellado; Richard M Ransohoff; Meizhang Li; Blanche Woehl; Helen Leung; Joanna Groom; Marcel Batten; Richard P Harvey; Carlos Martínez-A; Charles R Mackay; Fabienne Mackay
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-05       Impact factor: 11.205

8.  SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation.

Authors:  Yan Zhu; Tomoko Matsumoto; Sakae Mikami; Takashi Nagasawa; Fujio Murakami
Journal:  Development       Date:  2009-06       Impact factor: 6.868

9.  Molecular cloning and structure of a pre-B-cell growth-stimulating factor.

Authors:  T Nagasawa; H Kikutani; T Kishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205

10.  Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin's lymphoma.

Authors:  John F DiPersio; Ivana N Micallef; Patrick J Stiff; Brian J Bolwell; Richard T Maziarz; Eric Jacobsen; Auayporn Nademanee; John McCarty; Gary Bridger; Gary Calandra
Journal:  J Clin Oncol       Date:  2009-08-31       Impact factor: 44.544
View more
  68 in total

1.  Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1.

Authors:  Jodi L Murakami; Baohui Xu; Christopher B Franco; Xingbin Hu; Stephen J Galli; Irving L Weissman; Ching-Cheng Chen
Journal:  Stem Cells Dev       Date:  2015-11-05       Impact factor: 3.272

2.  Gab1 regulates SDF-1-induced progression via inhibition of apoptosis pathway induced by PI3K/AKT/Bcl-2/BAX pathway in human chondrosarcoma.

Authors:  Yongqian Fan; Fengjian Yang; Xuhai Cao; Cong Chen; Xuelin Zhang; Xu Zhang; Weilong Lin; Xiaofeng Wang; Chengwei Liang
Journal:  Tumour Biol       Date:  2015-08-16

3.  Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis.

Authors:  Pierre-Michaël Coly; Nicolas Perzo; Vadim Le Joncour; Céline Lecointre; Marie-Thérèse Schouft; Laurence Desrues; Marie-Christine Tonon; Olivier Wurtz; Pierrick Gandolfo; Hélène Castel; Fabrice Morin
Journal:  Autophagy       Date:  2016-10-07       Impact factor: 16.016

4.  Role of Prx1-expressing skeletal cells and Prx1-expression in fracture repair.

Authors:  Alessandra Esposito; Lai Wang; Tieshi Li; Mariana Miranda; Anna Spagnoli
Journal:  Bone       Date:  2020-07-03       Impact factor: 4.398

5.  The promise of stromal cell-derived factor-1 in novel heart disease treatments.

Authors:  Friedrich C Luft
Journal:  J Mol Med (Berl)       Date:  2017-08       Impact factor: 4.599

6.  Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model.

Authors:  Adib Zendedel; Sonja Johann; Soraya Mehrabi; Mohammad-Taghi Joghataei; Gholamreza Hassanzadeh; Markus Kipp; Cordian Beyer
Journal:  Mol Neurobiol       Date:  2015-05-14       Impact factor: 5.590

7.  Integration of gene expression data identifies key genes and pathways in colorectal cancer.

Authors:  Hossein Hozhabri; Ali Lashkari; Seyed-Morteza Razavi; Ali Mohammadian
Journal:  Med Oncol       Date:  2021-01-07       Impact factor: 3.064

8.  Association of Plasma SDF-1 with Bone Mineral Density, Body Composition, and Hip Fractures in Older Adults: The Cardiovascular Health Study.

Authors:  Laura D Carbone; Petra Bůžková; Howard A Fink; John A Robbins; Monique Bethel; Mark W Hamrick; William D Hill
Journal:  Calcif Tissue Int       Date:  2017-02-28       Impact factor: 4.333

Review 9.  Pancreatic cancer stem cell markers and exosomes - the incentive push.

Authors:  Sarah Heiler; Zhe Wang; Margot Zöller
Journal:  World J Gastroenterol       Date:  2016-07-14       Impact factor: 5.742

Review 10.  Extracellular molecules in hematopoietic stem cell mobilisation.

Authors:  Linda Bendall
Journal:  Int J Hematol       Date:  2016-11-08       Impact factor: 2.490
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.