Giacomo Bellani1, Antonio Pesenti. 1. aDepartment of Health Science, University of Milan-Bicocca bDepartment of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy.
Abstract
PURPOSE OF REVIEW: Spontaneous breathing has been shown to induce both positive and negative effects on the function and on injury of lungs and diaphragm during critical illness; thus, monitoring of the breathing effort generated by the patient might be valuable for a better understanding of the mechanisms of disease and to set properly ventilation. The purpose of this review is to summarize the recent findings on the different techniques available to measure the patient's breathing effort, mainly during spontaneous assisted ventilation. RECENT FINDINGS: Although esophageal pressure measurement remains the solid reference technique to quantitate the breathing effort, other tools have been developed and tested. These include the diaphragmatic electromyogram, whose voltage is linearly related to the pressure generated by the diaphragm, ultrasound, which relies on the measurement of diaphragmatic displacement or thickening, and other approaches, which derive breathing effort solely from the airway flow and pressure tracings. SUMMARY: The development of measurement techniques and their introduction in clinical practice will allow us to understand the role of spontaneous breathing effort in the pathophysiology of lung injury and weaning failure, and how to adjust the breathing workload in an individual patient.
PURPOSE OF REVIEW: Spontaneous breathing has been shown to induce both positive and negative effects on the function and on injury of lungs and diaphragm during critical illness; thus, monitoring of the breathing effort generated by the patient might be valuable for a better understanding of the mechanisms of disease and to set properly ventilation. The purpose of this review is to summarize the recent findings on the different techniques available to measure the patient's breathing effort, mainly during spontaneous assisted ventilation. RECENT FINDINGS: Although esophageal pressure measurement remains the solid reference technique to quantitate the breathing effort, other tools have been developed and tested. These include the diaphragmatic electromyogram, whose voltage is linearly related to the pressure generated by the diaphragm, ultrasound, which relies on the measurement of diaphragmatic displacement or thickening, and other approaches, which derive breathing effort solely from the airway flow and pressure tracings. SUMMARY: The development of measurement techniques and their introduction in clinical practice will allow us to understand the role of spontaneous breathing effort in the pathophysiology of lung injury and weaning failure, and how to adjust the breathing workload in an individual patient.
Authors: Ken Kato; Victoria L Cammann; L Christian Napp; Konrad A Szawan; Jozef Micek; Sara Dreiding; Rena A Levinson; Vanya Petkova; Michael Würdinger; Alexandru Patrascu; Rafael Sumalinog; Sebastiano Gili; Christian F Clarenbach; Malcolm Kohler; Manfred Wischnewsky; Rodolfo Citro; Carmine Vecchione; Eduardo Bossone; Michael Neuhaus; Jennifer Franke; Benjamin Meder; Milosz Jaguszewski; Michel Noutsias; Maike Knorr; Susanne Heiner; Fabrizio D'Ascenzo; Wolfgang Dichtl; Christof Burgdorf; Behrouz Kherad; Carsten Tschöpe; Annahita Sarcon; Jerold Shinbane; Lawrence Rajan; Guido Michels; Roman Pfister; Alessandro Cuneo; Claudius Jacobshagen; Mahir Karakas; Wolfgang Koenig; Alexander Pott; Philippe Meyer; Marco Roffi; Adrian Banning; Mathias Wolfrum; Florim Cuculi; Richard Kobza; Thomas A Fischer; Tuija Vasankari; K E Juhani Airaksinen; Monika Budnik; Rafal Dworakowski; Philip MacCarthy; Christoph Kaiser; Stefan Osswald; Leonarda Galiuto; Christina Chan; Paul Bridgman; Daniel Beug; Clément Delmas; Olivier Lairez; Ekaterina Gilyarova; Alexandra Shilova; Mikhail Gilyarov; Ibrahim El-Battrawy; Ibrahim Akin; Martin Kozel; Petr Tousek; David E Winchester; Jan Galuszka; Christian Ukena; Gregor Poglajen; Pedro Carrilho-Ferreira; Christian Hauck; Carla Paolini; Claudio Bilato; Masanori Sano; Iwao Ishibashi; Masayuki Takahara; Toshiharu Himi; Yoshio Kobayashi; Abhiram Prasad; Charanjit S Rihal; Kan Liu; P Christian Schulze; Matteo Bianco; Lucas Jörg; Hans Rickli; Gonçalo Pestana; Thanh H Nguyen; Michael Böhm; Lars S Maier; Fausto J Pinto; Petr Widimský; Stephan B Felix; Grzegorz Opolski; Ruediger C Braun-Dullaeus; Wolfgang Rottbauer; Gerd Hasenfuß; Burkert M Pieske; Heribert Schunkert; Martin Borggrefe; Holger Thiele; Johann Bauersachs; Hugo A Katus; John D Horowitz; Carlo Di Mario; Thomas Münzel; Filippo Crea; Jeroen J Bax; Thomas F Lüscher; Frank Ruschitzka; Jelena R Ghadri; Christian Templin Journal: ESC Heart Fail Date: 2021-03-13