Literature DB >> 24719533

Use of large osteochondral allografts in reconstruction of traumatic uncontained distal femoral defects.

Richard Fagan1, Andrew J Furey2.   

Abstract

UNLABELLED: Large osteoarticular injuries with subchondral bone loss involving the knee in young active patients often result in significant morbidity and loss of normal joint function. A review of the current literature reveals that multiple surgical management options are currently employed, however there is no consensus on standard of care. Osteochondral allografting provides an attractive alternative treatment option for the repair of large articular defects of the knee.
METHODS: In this article we present the case of a young male who suffered traumatic intraarticular bone loss secondary to a grade IIIA distal femoral fracture and subsequently underwent reconstruction of his medial femoral condyle using a fresh-frozen osteochondral allograft.
RESULTS: We present the radiographic and functional outcome of this patient at two years post-operative. The range of motion of the knee was 0-130° and the patient's post-operative functional outcome was evaluated using the Knee injury and Osteoarthritis Outcome Score (KOOS), which was 76%.
CONCLUSIONS: While further research is required, the results of our case study concur with the current body of literature supporting the use of fresh-frozen osteochondral allograft as a reconstructive option for treating large traumatic intraarticular lesions involving the distal femur.

Entities:  

Keywords:  Distal femur; Intraarticular; Osteochondral allograft; Traumatic knee defects

Year:  2014        PMID: 24719533      PMCID: PMC3978744          DOI: 10.1016/j.jor.2013.12.003

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  27 in total

Review 1.  Osteochondral allografts in the treatment of articular cartilage injuries of the knee.

Authors:  Alex Hennig; Joseph Abate
Journal:  Sports Med Arthrosc Rev       Date:  2007-09       Impact factor: 1.985

2.  Osteochondral resurfacing of the knee joint with allograft. Clinical analysis of 33 cases.

Authors:  A Bakay; L Csönge; G Papp; L Fekete
Journal:  Int Orthop       Date:  1998       Impact factor: 3.075

3.  A clinical and histologic analysis of failed fresh osteochondral allografts.

Authors:  R D Oakeshott; I Farine; K P Pritzker; F Langer; A E Gross
Journal:  Clin Orthop Relat Res       Date:  1988-08       Impact factor: 4.176

4.  Arthroscopic autogenous osteochondral mosaicplasty for the treatment of femoral condylar articular defects. A preliminary report.

Authors:  L Hangody; G Kish; Z Kárpáti; I Szerb; I Udvarhelyi
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  1997       Impact factor: 4.342

5.  Fresh osteochondral allografts for post-traumatic osteochondral defects of the knee.

Authors:  M T Ghazavi; K P Pritzker; A M Davis; A E Gross
Journal:  J Bone Joint Surg Br       Date:  1997-11

Review 6.  Allografts in articular cartilage repair.

Authors:  Simon Görtz; William D Bugbee
Journal:  Instr Course Lect       Date:  2007

7.  Chondrocyte viability in fresh and frozen large human osteochondral allografts: effect of cryoprotective agents.

Authors:  F Judas; S Rosa; L Teixeira; C Lopes; A Ferreira Mendes
Journal:  Transplant Proc       Date:  2007-10       Impact factor: 1.066

8.  The viability of articular cartilage in fresh osteochondral allografts after clinical transplantation.

Authors:  A A Czitrom; S Keating; A E Gross
Journal:  J Bone Joint Surg Am       Date:  1990-04       Impact factor: 5.284

9.  Refrigerated osteoarticular allografts to treat articular cartilage defects of the femoral condyles. A prospective outcomes study.

Authors:  Robert F LaPrade; Jesse Botker; Mary Herzog; Julie Agel
Journal:  J Bone Joint Surg Am       Date:  2009-04       Impact factor: 5.284

10.  Resurfacing of the knee with fresh osteochondral allograft.

Authors:  M H Meyers; W Akeson; F R Convery
Journal:  J Bone Joint Surg Am       Date:  1989-06       Impact factor: 5.284

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