Literature DB >> 9393922

Fresh osteochondral allografts for post-traumatic osteochondral defects of the knee.

M T Ghazavi1, K P Pritzker, A M Davis, A E Gross.   

Abstract

We used fresh small-fragment osteochondral allografts to reconstruct post-traumatic osteochondral defects in 126 knees of 123 patients with a mean age of 35 years. At a mean follow-up of 7.5 years (2 to 20), 108 knees were rated as successful (85%) and 18 had failed (15%). The factors related to failure included age over 50 years (p = 0.008), bipolar defects (p < 0.05), malaligned knees with overstressing of the grafts, and workers' compensation cases (p < 0.04). Collapse of the graft by more than 3 mm and of the joint space of more than 50% were seen more frequently in radiographs of failed grafts. Our encouraging clinical results for fresh small-fragment osteochondral allografts show that they are indicated for unipolar post-traumatic osteochondral defects of the knee in young active patients.

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Year:  1997        PMID: 9393922     DOI: 10.1302/0301-620x.79b6.7534

Source DB:  PubMed          Journal:  J Bone Joint Surg Br        ISSN: 0301-620X


  56 in total

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Review 4.  Management of knee articular cartilage injuries in athletes: chondroprotection, chondrofacilitation, and resurfacing.

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5.  Fresh osteochondral allografts for posttraumatic knee defects: long-term followup.

Authors:  A E Gross; W Kim; F Las Heras; D Backstein; O Safir; K P H Pritzker
Journal:  Clin Orthop Relat Res       Date:  2008-05-09       Impact factor: 4.176

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Review 7.  A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from König to the ROCK study group.

Authors:  Eric W Edmonds; John Polousky
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8.  The safety and efficacy of magnetic targeting using autologous mesenchymal stem cells for cartilage repair.

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9.  Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix.

Authors:  Nai-Chen Cheng; Bradley T Estes; Hani A Awad; Farshid Guilak
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Review 10.  The subchondral bone in articular cartilage repair: current problems in the surgical management.

Authors:  Andreas H Gomoll; Henning Madry; Gunnar Knutsen; Niek van Dijk; Romain Seil; Mats Brittberg; Elizaveta Kon
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-02-04       Impact factor: 4.342

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