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Literature DB >> 24719442

Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents.

Yanan Zhao¹, Emilian Armeanu², Richard DiVerniero³, Terri A Lewis⁴, Richard C Dobson⁵, Dimitrios P Kontoyiannis⁶, Emmanuel Roilides⁷, Thomas J Walsh⁸, David S Perlin⁹.

Abstract

Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2014 PMID： 24719442 PMCID： PMC4042738 DOI： 10.1128/JCM.00854-14

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

17 in total

1. Contaminations occurring in fungal PCR assays.

Authors: J Loeffler; H Hebart; R Bialek; L Hagmeyer; D Schmidt; F P Serey; M Hartmann; J Eucker; H Einsele
Journal: J Clin Microbiol Date: 1999-04 Impact factor: 5.948

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Authors: J A Horvath; S Dummer
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Review 3. Meningitis caused by Filobasidium uniguttulatum: case report and overview of the literature.

Authors: Weihua Pan; Wanqing Liao; Ferry Hagen; Bart Theelen; Weimin Shi; Jacques F Meis; Teun Boekhout
Journal: Mycoses Date: 2011-07-06 Impact factor: 4.377

4. A real-time PCR assay for rapid detection and quantification of Exserohilum rostratum, a causative pathogen of fungal meningitis associated with injection of contaminated methylprednisolone.

Authors: Yanan Zhao; Ruta Petraitiene; Thomas J Walsh; David S Perlin
Journal: J Clin Microbiol Date: 2013-01-09 Impact factor: 5.948

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Authors: Carol A Kauffman; Peter G Pappas; Thomas F Patterson
Journal: N Engl J Med Date: 2012-10-19 Impact factor: 91.245

Review 6. Aureobasidium pullulans infection: fungemia in an infant and a review of human cases.

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Journal: Diagn Microbiol Infect Dis Date: 2005-03 Impact factor: 2.803

7. Comparison of non-culture-based methods for detection of systemic fungal infections, with an emphasis on invasive Candida infections.

Authors: P Lewis White; Alice E Archer; Rosemary A Barnes
Journal: J Clin Microbiol Date: 2005-05 Impact factor: 5.948

8. Aspergillus DNA contamination in blood collection tubes.

Authors: Elizabeth Harrison; Thomas Stalhberger; Ruth Whelan; Michele Sugrue; John R Wingard; Barbara D Alexander; Sarah A Follett; Paul Bowyer; David W Denning
Journal: Diagn Microbiol Infect Dis Date: 2010-08 Impact factor: 2.803

9. Rapid real-time nucleic Acid sequence-based amplification-molecular beacon platform to detect fungal and bacterial bloodstream infections.

Authors: Yanan Zhao; Steven Park; Barry N Kreiswirth; Christine C Ginocchio; Raphaël Veyret; Ali Laayoun; Alain Troesch; David S Perlin
Journal: J Clin Microbiol Date: 2009-04-29 Impact factor: 5.948

4. Utility of real-time PCR for detection of Exserohilum rostratum in body and tissue fluids during the multistate outbreak of fungal meningitis and other infections.

Authors: Lalitha Gade; Dale E Grgurich; Thomas M Kerkering; Mary E Brandt; Anastasia P Litvintseva
Journal: J Clin Microbiol Date: 2014-12-17 Impact factor: 5.948

4 in total