Literature DB >> 24719415

Viral and cellular FLICE-inhibitory proteins: a comparison of their roles in regulating intrinsic immune responses.

Joanna L Shisler1.   

Abstract

FLICE-inhibitory proteins (FLIPs) are a family of viral (poxvirus and herpesvirus) and cellular proteins. The hallmark of this family is the presence of tandem death-effector domains (DEDs). Despite this shared motif, each protein possesses different abilities to modulate apoptosis, NF-κB, and interferon regulatory factor 3 (IRF3). These similarities and differences are discussed and highlighted here. The comparative study of FLIPs provides a unique basis to understand virus-host interactions, viral pathogenesis, and cellular regulation of immune system signal transduction pathways.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24719415      PMCID： PMC4054373          DOI： 10.1128/JVI.00276-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

Review 1.  Structural basis of signal transduction in the TNF receptor superfamily.

Authors:  Jixi Li; Qian Yin; Hao Wu
Journal:  Adv Immunol       Date:  2013       Impact factor: 3.543

2.  Fas-associated death domain-containing protein-mediated antiviral innate immune signaling involves the regulation of Irf7.

Authors:  Siddharth Balachandran; Thiagarajan Venkataraman; Paul B Fisher; Glen N Barber
Journal:  J Immunol       Date:  2007-02-15       Impact factor: 5.422

3.  Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.

Authors:  M Thome; P Schneider; K Hofmann; H Fickenscher; E Meinl; F Neipel; C Mattmann; K Burns; J L Bodmer; M Schröter; C Scaffidi; P H Krammer; M E Peter; J Tschopp
Journal:  Nature       Date:  1997-04-03       Impact factor: 49.962

4.  Inhibition of death receptor signals by cellular FLIP.

Authors:  M Irmler; M Thome; M Hahne; P Schneider; K Hofmann; V Steiner; J L Bodmer; M Schröter; K Burns; C Mattmann; D Rimoldi; L E French; J Tschopp
Journal:  Nature       Date:  1997-07-10       Impact factor: 49.962

5.  The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex.

Authors:  Li Liu; Michael T Eby; Nisha Rathore; Suwan K Sinha; Arvind Kumar; Preet M Chaudhary
Journal:  J Biol Chem       Date:  2002-02-05       Impact factor: 5.157

6.  The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation.

Authors:  Qinmiao Sun; Sunny Zachariah; Preet M Chaudhary
Journal:  J Biol Chem       Date:  2003-10-16       Impact factor: 5.157

7.  A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis.

Authors:  S Hu; C Vincenz; M Buller; V M Dixit
Journal:  J Biol Chem       Date:  1997-04-11       Impact factor: 5.157

8.  Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virus.

Authors:  Crystal M H Randall; Sunetra Biswas; Catherine V Selen; Joanna L Shisler
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-30       Impact factor: 11.205

9.  FLIP (Flice-like inhibitory protein) suppresses cytoplasmic double-stranded-RNA-induced apoptosis and NF-κB and IRF3-mediated signaling.

Authors:  Priya Handa; Joan C Tupper; Katherine C Jordan; John M Harlan
Journal:  Cell Commun Signal       Date:  2011-06-02       Impact factor: 5.712

10.  The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.

Authors:  Alexander Golks; Dirk Brenner; Peter H Krammer; Inna N Lavrik
Journal:  J Exp Med       Date:  2006-05-08       Impact factor: 14.307
View more
  6 in total

Review 1.  In Vivo Models of Oncoproteins Encoded by Kaposi's Sarcoma-Associated Herpesvirus.

Authors:  Ariana G Bravo Cruz; Blossom Damania
Journal:  J Virol       Date:  2019-05-15       Impact factor: 5.103

2.  Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.

Authors:  Chiara Musiu; Simone Caligola; Alessandra Fiore; Alessia Lamolinara; Cristina Frusteri; Francesco Domenico Del Pizzo; Francesco De Sanctis; Stefania Canè; Annalisa Adamo; Francesca Hofer; Roza Maria Barouni; Andrea Grilli; Serena Zilio; Paolo Serafini; Evelina Tacconelli; Katia Donadello; Leonardo Gottin; Enrico Polati; Domenico Girelli; Ildo Polidoro; Piera Amelia Iezzi; Domenico Angelucci; Andrea Capece; Ying Chen; Zheng-Li Shi; Peter J Murray; Marco Chilosi; Ido Amit; Silvio Bicciato; Manuela Iezzi; Vincenzo Bronte; Stefano Ugel
Journal:  Cell Death Differ       Date:  2021-09-13       Impact factor: 12.067

3.  Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Induces the Oncogenic miR-17-92 Cluster and Down-Regulates TGF-β Signaling.

Authors:  Hong Seok Choi; Vaibhav Jain; Brian Krueger; Vickie Marshall; Chang Hee Kim; Joanna L Shisler; Denise Whitby; Rolf Renne
Journal:  PLoS Pathog       Date:  2015-11-06       Impact factor: 6.823

Review 4.  Poxviral Targeting of Interferon Regulatory Factor Activation.

Authors:  Clara Lawler; Gareth Brady
Journal:  Viruses       Date:  2020-10-20       Impact factor: 5.048

Review 5.  FLIP(L): the pseudo-caspase.

Authors:  Peter Smyth; Tamas Sessler; Christopher J Scott; Daniel B Longley
Journal:  FEBS J       Date:  2020-03-12       Impact factor: 5.542

Review 6.  Coronavirus Infection-Associated Cell Death Signaling and Potential Therapeutic Targets.

Authors:  Rittibet Yapasert; Patompong Khaw-On; Ratana Banjerdpongchai
Journal:  Molecules       Date:  2021-12-09       Impact factor: 4.411
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.