Literature DB >> 2471522

Production of monocyte chemotactic and activating factor (MCAF) by human dermal fibroblasts in response to interleukin 1 or tumor necrosis factor.

C G Larsen1, C O Zachariae, J J Oppenheim, K Matsushima.   

Abstract

Normal human dermal fibroblasts rapidly expressed (less than 30 min.) considerable mRNA for monocyte chemotactic and activating factor (MCAF) and released high levels of biological activity in response to interleukin 1 (IL 1) or tumor necrosis factor (TNF). In contrast, cultured normal human keratinocytes did not express MCAF mRNA when stimulated with IL 1 or TNF. These results suggest the important role of dermal fibroblasts, the predominant cells in dermal connective tissue, in the recruitment of monocytes during inflammation. This is the first report of the induction of MCAF by IL 1 or TNF in any cell type.

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Year:  1989        PMID: 2471522     DOI: 10.1016/s0006-291x(89)80160-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  24 in total

1.  Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1.

Authors:  M L Rand; J S Warren; M K Mansour; W Newman; D J Ringler
Journal:  Am J Pathol       Date:  1996-03       Impact factor: 4.307

2.  Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.

Authors:  F Marra; R DeFranco; C Grappone; S Milani; S Pastacaldi; M Pinzani; R G Romanelli; G Laffi; P Gentilini
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3.  Macrophage inflammatory protein-1 alpha expression in non-neoplastic and neoplastic lung tissue.

Authors:  T Konishi; H Okabe; H Katoh; Y Fujiyama; A Mori
Journal:  Virchows Arch       Date:  1996-05       Impact factor: 4.064

4.  Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis.

Authors:  A E Koch; S L Kunkel; L A Harlow; B Johnson; H L Evanoff; G K Haines; M D Burdick; R M Pope; R M Strieter
Journal:  J Clin Invest       Date:  1992-09       Impact factor: 14.808

5.  Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation.

Authors:  L Mazzucchelli; C Hauser; K Zgraggen; H Wagner; M Hess; J A Laissue; C Mueller
Journal:  Am J Pathol       Date:  1994-05       Impact factor: 4.307

6.  Chemokine response in mice infected with Mycobacterium tuberculosis.

Authors:  E R Rhoades; A M Cooper; I M Orme
Journal:  Infect Immun       Date:  1995-10       Impact factor: 3.441

7.  The production of chemotactic cytokines in an allogeneic response. The role of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-3.

Authors:  N W Lukacs; S L Kunkel; M D Burdick; R M Strieter
Journal:  Am J Pathol       Date:  1993-10       Impact factor: 4.307

8.  Human corneal interleukin-8. IL-1 and TNF-induced gene expression and secretion.

Authors:  V M Elner; R M Strieter; M A Pavilack; S G Elner; D G Remick; J M Danforth; S L Kunkel
Journal:  Am J Pathol       Date:  1991-11       Impact factor: 4.307

9.  Expression of monocyte chemoattractant protein 1 (MCP-1) in adult periodontal disease: increased monocyte chemotactic activity in crevicular fluids and induction of MCP-1 expression in gingival tissues.

Authors:  S Hanazawa; Y Kawata; A Takeshita; H Kumada; M Okithu; S Tanaka; Y Yamamoto; T Masuda; T Umemoto; S Kitano
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

10.  High levels of interleukin-1 in patients with endemic pemphigus foliaceus.

Authors:  Denise Bertulucci Rocha-Rodrigues; Giovana Paschoini; Sanivia Aparecida Lima Pereira; Marlene Antonia dos Reis; Vicente de Paula Antunes Teixeira; Virmondes Rodrigues Júnior
Journal:  Clin Diagn Lab Immunol       Date:  2003-09
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