Literature DB >> 24709663

Prevalence of heart failure signs and symptoms in a large primary care population identified through the use of text and data mining of the electronic health record.

Rajakrishnan Vijayakrishnan1, Steven R Steinhubl2, Kenney Ng3, Jimeng Sun4, Roy J Byrd3, Zahra Daar1, Brent A Williams1, Christopher deFilippi5, Shahram Ebadollahi3, Walter F Stewart6.   

Abstract

BACKGROUND: The electronic health record (EHR) contains a tremendous amount of data that if appropriately detected can lead to earlier identification of disease states such as heart failure (HF). Using a novel text and data analytic tool we explored the longitudinal EHR of over 50,000 primary care patients to identify the documentation of the signs and symptoms of HF in the years preceding its diagnosis. METHODS AND
RESULTS: Retrospective analysis consisted of 4,644 incident HF cases and 45,981 group-matched control subjects. Documentation of Framingham HF signs and symptoms within encounter notes were carried out with the use of a previously validated natural language processing procedure. A total of 892,805 affirmed criteria were documented over an average observation period of 3.4 years. Among eventual HF cases, 85% had ≥1 criterion within 1 year before their HF diagnosis, as did 55% of control subjects. Substantial variability in the prevalence of individual signs and symptoms were found in both case and control subjects.
CONCLUSIONS: HF signs and symptoms are frequently documented in a primary care population as identified through automated text and data mining of EHRs. Their frequent identification demonstrates the rich data available within EHRs that will allow for future work on automated criterion identification to help develop predictive models for HF.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Heart failure; electronic health records; natural language processing

Mesh:

Year:  2014        PMID: 24709663      PMCID: PMC4083004          DOI: 10.1016/j.cardfail.2014.03.008

Source DB:  PubMed          Journal:  J Card Fail        ISSN: 1071-9164            Impact factor:   5.712


  17 in total

1.  Barriers to accurate diagnosis and effective management of heart failure in primary care: qualitative study.

Authors:  Ahmet Fuat; A Pali S Hungin; Jeremy James Murphy
Journal:  BMJ       Date:  2003-01-25

2.  Classification of heart failure in population based research: an assessment of six heart failure scores.

Authors:  A Mosterd; J W Deckers; A W Hoes; A Nederpel; A Smeets; D T Linker; D E Grobbee
Journal:  Eur J Epidemiol       Date:  1997-07       Impact factor: 8.082

3.  Generating Clinical Notes for Electronic Health Record Systems.

Authors:  S Trent Rosenbloom; William W Stead; Joshua C Denny; Dario Giuse; Nancy M Lorenzi; Steven H Brown; Kevin B Johnson
Journal:  Appl Clin Inform       Date:  2010-01-01       Impact factor: 2.342

4.  Prediction modeling using EHR data: challenges, strategies, and a comparison of machine learning approaches.

Authors:  Jionglin Wu; Jason Roy; Walter F Stewart
Journal:  Med Care       Date:  2010-06       Impact factor: 2.983

Review 5.  The genomic architecture of sporadic heart failure.

Authors:  Gerald W Dorn
Journal:  Circ Res       Date:  2011-05-13       Impact factor: 17.367

6.  Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease.

Authors:  Frans H Rutten; Maarten-Jan M Cramer; Diederick E Grobbee; Alfred P E Sachs; Johannes H Kirkels; Jan-Willem J Lammers; Arno W Hoes
Journal:  Eur Heart J       Date:  2005-04-28       Impact factor: 29.983

7.  Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study.

Authors:  Justin T Saunders; Vijay Nambi; James A de Lemos; Lloyd E Chambless; Salim S Virani; Eric Boerwinkle; Ron C Hoogeveen; Xiaoxi Liu; Brad C Astor; Thomas H Mosley; Aaron R Folsom; Gerardo Heiss; Josef Coresh; Christie M Ballantyne
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8.  Biochemical detection of left-ventricular systolic dysfunction.

Authors:  T A McDonagh; S D Robb; D R Murdoch; J J Morton; I Ford; C E Morrison; H Tunstall-Pedoe; J J McMurray; H J Dargie
Journal:  Lancet       Date:  1998-01-03       Impact factor: 79.321

9.  Γ-glutamyltransferase, hepatic enzymes, and risk of incident heart failure in older men.

Authors:  S Goya Wannamethee; Peter H Whincup; A Gerald Shaper; Lucy Lennon; Naveed Sattar
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-01-05       Impact factor: 8.311

10.  Automatic identification of heart failure diagnostic criteria, using text analysis of clinical notes from electronic health records.

Authors:  Roy J Byrd; Steven R Steinhubl; Jimeng Sun; Shahram Ebadollahi; Walter F Stewart
Journal:  Int J Med Inform       Date:  2013-01-11       Impact factor: 4.046

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  28 in total

1.  Characterizing Physicians Practice Phenotype from Unstructured Electronic Health Records.

Authors:  Sanjoy Dey; Yajuan Wang; Roy J Byrd; Kenney Ng; Steven R Steinhubl; Christopher deFilippi; Walter F Stewart
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

Review 2.  Clinical Natural Language Processing in 2014: Foundational Methods Supporting Efficient Healthcare.

Authors:  A Névéol; P Zweigenbaum
Journal:  Yearb Med Inform       Date:  2015-08-13

3.  Early Detection of Heart Failure Using Electronic Health Records: Practical Implications for Time Before Diagnosis, Data Diversity, Data Quantity, and Data Density.

Authors:  Kenney Ng; Steven R Steinhubl; Christopher deFilippi; Sanjoy Dey; Walter F Stewart
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2016-11-08

Review 4.  Aspiring to Unintended Consequences of Natural Language Processing: A Review of Recent Developments in Clinical and Consumer-Generated Text Processing.

Authors:  D Demner-Fushman; N Elhadad
Journal:  Yearb Med Inform       Date:  2016-11-10

5.  Patient and healthcare provider views on a patient-reported outcomes portal.

Authors:  Robert M Cronin; Douglas Conway; David Condon; Rebecca N Jerome; Daniel W Byrne; Paul A Harris
Journal:  J Am Med Inform Assoc       Date:  2018-11-01       Impact factor: 4.497

Review 6.  Big data analytics to improve cardiovascular care: promise and challenges.

Authors:  John S Rumsfeld; Karen E Joynt; Thomas M Maddox
Journal:  Nat Rev Cardiol       Date:  2016-03-24       Impact factor: 32.419

7.  GRAM: Graph-based Attention Model for Healthcare Representation Learning.

Authors:  Edward Choi; Mohammad Taha Bahadori; Le Song; Walter F Stewart; Jimeng Sun
Journal:  KDD       Date:  2017-08

8.  Management of the heart failure patient in the primary care setting.

Authors:  Weiliang Huang; Shao Guang Sheldon Lee; Choon How How
Journal:  Singapore Med J       Date:  2020-05       Impact factor: 1.858

9.  Psychometric Analysis of the Heart Failure Somatic Perception Scale as a Measure of Patient Symptom Perception.

Authors:  Corrine Y Jurgens; Christopher S Lee; Barbara Riegel
Journal:  J Cardiovasc Nurs       Date:  2017 Mar/Apr       Impact factor: 2.083

10.  Natural language processing of symptoms documented in free-text narratives of electronic health records: a systematic review.

Authors:  Theresa A Koleck; Caitlin Dreisbach; Philip E Bourne; Suzanne Bakken
Journal:  J Am Med Inform Assoc       Date:  2019-04-01       Impact factor: 4.497

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