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Literature DB >> 24700296

Polymeric micelles: nanocarriers for cancer-targeted drug delivery.

Abstract

Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10-100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation. In this review, the importance of rational design was highlighted by summarizing the recent progress on the development of micellar formulations. Emphasis is placed on the new strategies to enhance the drug/carrier interaction for improved drug-loading capacity. In addition, the micelle-forming drug-polymer conjugates are also discussed which have both drug-loading function and antitumor activity.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2014 PMID： 24700296 PMCID： PMC4113619 DOI： 10.1208/s12249-014-0113-z

Source DB: PubMed Journal: AAPS PharmSciTech ISSN： 1530-9932 Impact factor: 3.246

118 in total

1. Paclitaxel nanocrystals for overcoming multidrug resistance in cancer.

Authors: Yang Liu; Leaf Huang; Feng Liu
Journal: Mol Pharm Date: 2010-06-07 Impact factor: 4.939

2. Shape effects of filaments versus spherical particles in flow and drug delivery.

Authors: Yan Geng; Paul Dalhaimer; Shenshen Cai; Richard Tsai; Manorama Tewari; Tamara Minko; Dennis E Discher
Journal: Nat Nanotechnol Date: 2007-03-25 Impact factor: 39.213

3. Antitumor, anti-inflammatory and analgesic property of embelin, a plant product.

Authors: M Chitra; E Sukumar; V Suja; C S Devi
Journal: Chemotherapy Date: 1994 Mar-Apr Impact factor: 2.544

4. Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs.

Authors: Ji Young Kim; Sungwon Kim; Rodolfo Pinal; Kinam Park
Journal: J Control Release Date: 2011-02-23 Impact factor: 9.776

5. Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: the lack of beneficial effects by coating liposomes with poly(ethylene glycol).

Authors: M J Parr; D Masin; P R Cullis; M B Bally
Journal: J Pharmacol Exp Ther Date: 1997-03 Impact factor: 4.030

6. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.

Authors: I Tamm; S M Kornblau; H Segall; S Krajewski; K Welsh; S Kitada; D A Scudiero; G Tudor; Y H Qui; A Monks; M Andreeff; J C Reed
Journal: Clin Cancer Res Date: 2000-05 Impact factor: 12.531

7. Hydrotropic solubilization of poorly water-soluble drugs.

Authors: Ji Young Kim; Sungwon Kim; Michelle Papp; Kinam Park; Rodolfo Pinal
Journal: J Pharm Sci Date: 2010-09 Impact factor: 3.534

8. Formulation of Docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS(2k)) micelles for targeted and synergistic chemotherapy.

Authors: Yu Mi; Yutao Liu; Si-Shen Feng
Journal: Biomaterials Date: 2011-06 Impact factor: 12.479

9. Hydrotropic solubilization of paclitaxel: analysis of chemical structures for hydrotropic property.

Authors: Jaehwi Lee; Sang Cheon Lee; Ghanashyam Acharya; Ching-jer Chang; Kinam Park
Journal: Pharm Res Date: 2003-07 Impact factor: 4.200

Review 10. Nanoparticle therapeutics: an emerging treatment modality for cancer.

Authors: Mark E Davis; Zhuo Georgia Chen; Dong M Shin
Journal: Nat Rev Drug Discov Date: 2008-09 Impact factor: 84.694

41 in total

1. Acoustic radiation force optical coherence elastography for evaluating mechanical properties of soft condensed matters and its biological applications.

Authors: Hsiao-Chuan Liu; Piotr Kijanka; Matthew W Urban
Journal: J Biophotonics Date: 2020-01-02 Impact factor: 3.207

2. Translational application of nano delivery systems: emerging cancer therapy.

Authors: Mahavir B Chougule; Chalet Tan
Journal: AAPS PharmSciTech Date: 2014-12-31 Impact factor: 3.246

3. Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel.

Authors: Tarek A Ahmed; Khalid M El-Say; Osama Aa Ahmed; Bader M Aljaeid
Journal: Int J Nanomedicine Date: 2019-07-23

Polymeric micelles: nanocarriers for cancer-targeted drug delivery.

1. Paclitaxel nanocrystals for overcoming multidrug resistance in cancer.

2. Shape effects of filaments versus spherical particles in flow and drug delivery.

3. Antitumor, anti-inflammatory and analgesic property of embelin, a plant product.

4. Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs.

5. Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: the lack of beneficial effects by coating liposomes with poly(ethylene glycol).

6. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.

7. Hydrotropic solubilization of poorly water-soluble drugs.

8. Formulation of Docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS(2k)) micelles for targeted and synergistic chemotherapy.

9. Hydrotropic solubilization of paclitaxel: analysis of chemical structures for hydrotropic property.

Review 10. Nanoparticle therapeutics: an emerging treatment modality for cancer.

1. Acoustic radiation force optical coherence elastography for evaluating mechanical properties of soft condensed matters and its biological applications.

2. Translational application of nano delivery systems: emerging cancer therapy.

3. Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel.

Review 4. Polymeric micelles and cancer therapy: an ingenious multimodal tumor-targeted drug delivery system.

Review 5. Nano to rescue: repository of nanocarriers for targeted drug delivery to curb breast cancer.

Review 6. Comprehensive comparison of theranostic nanoparticles in breast cancer.

7. Applications of nanoparticle drug delivery systems for the reversal of multidrug resistance in cancer.

Review 8. The potential of micelleplexes as a therapeutic strategy for osteosarcoma disease.

Review 9. Nanovectorization of Prostate Cancer Treatment Strategies: A New Approach to Improved Outcomes.

Review 10. Advances in Nano-Enabled Platforms for the Treatment of Depression.